JPS619A - 活性薬剤濃度分布が改良一定放出のためのシグモイダル濃度勾配を含む活性薬剤含有ヒドロゲルデバイス、その製造方法および使用 - Google Patents

活性薬剤濃度分布が改良一定放出のためのシグモイダル濃度勾配を含む活性薬剤含有ヒドロゲルデバイス、その製造方法および使用

Info

Publication number
JPS619A
JPS619A JP60098182A JP9818285A JPS619A JP S619 A JPS619 A JP S619A JP 60098182 A JP60098182 A JP 60098182A JP 9818285 A JP9818285 A JP 9818285A JP S619 A JPS619 A JP S619A
Authority
JP
Japan
Prior art keywords
active agent
hydrogel
bead
release
swollen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60098182A
Other languages
English (en)
Japanese (ja)
Inventor
ピン　アイ．リー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS619A publication Critical patent/JPS619A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Steroid Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Colloid Chemistry (AREA)
JP60098182A 1984-05-10 1985-05-10 活性薬剤濃度分布が改良一定放出のためのシグモイダル濃度勾配を含む活性薬剤含有ヒドロゲルデバイス、その製造方法および使用 Pending JPS619A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/608,756 US4624848A (en) 1984-05-10 1984-05-10 Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US608756 1984-05-10

Publications (1)

Publication Number Publication Date
JPS619A true JPS619A (ja) 1986-01-06

Family

ID=24437841

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60098182A Pending JPS619A (ja) 1984-05-10 1985-05-10 活性薬剤濃度分布が改良一定放出のためのシグモイダル濃度勾配を含む活性薬剤含有ヒドロゲルデバイス、その製造方法および使用

Country Status (16)

Country Link
US (1) US4624848A (oth)
EP (1) EP0164311B1 (oth)
JP (1) JPS619A (oth)
AT (1) ATE61731T1 (oth)
AU (1) AU583507B2 (oth)
CA (1) CA1246447A (oth)
DE (1) DE3582193D1 (oth)
DK (1) DK205185A (oth)
ES (1) ES542948A0 (oth)
FI (1) FI851801L (oth)
GR (1) GR851114B (oth)
IL (1) IL75129A (oth)
NZ (1) NZ212030A (oth)
PH (1) PH24100A (oth)
PT (1) PT80416B (oth)
ZA (1) ZA853511B (oth)

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JP2005507925A (ja) * 2001-10-29 2005-03-24 セリックス， インコーポレイテッド 三次元印刷により製造されたゼロ次放出プロフィール投薬形態のような徐放投薬形態を製造するためのシステム

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US4784499A (en) * 1986-03-13 1988-11-15 Daido Metal Company Ltd. Bearing unit
JP2005507925A (ja) * 2001-10-29 2005-03-24 セリックス， インコーポレイテッド 三次元印刷により製造されたゼロ次放出プロフィール投薬形態のような徐放投薬形態を製造するためのシステム

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ATE61731T1 (de) 1991-04-15
FI851801A0 (fi) 1985-05-08
US4624848A (en) 1986-11-25
EP0164311B1 (en) 1991-03-20
PT80416B (en) 1987-04-16
FI851801A7 (fi) 1985-11-11
AU4221685A (en) 1985-11-14
ZA853511B (en) 1985-12-24
DE3582193D1 (de) 1991-04-25
CA1246447A (en) 1988-12-13
IL75129A (en) 1989-08-15
ES8603273A1 (es) 1986-01-01
GR851114B (oth) 1985-11-25
IL75129A0 (en) 1985-09-29
AU583507B2 (en) 1989-05-04
FI851801L (fi) 1985-11-11
NZ212030A (en) 1988-01-08
PH24100A (en) 1990-03-05
DK205185D0 (da) 1985-05-09
EP0164311A2 (en) 1985-12-11
ES542948A0 (es) 1986-01-01
DK205185A (da) 1985-11-11
PT80416A (en) 1985-06-01
EP0164311A3 (en) 1987-06-03

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