JPS6040423B2 - ユーフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン類 - Google Patents

ユーフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン類

Info

Publication number
JPS6040423B2
JPS6040423B2 JP53004769A JP476978A JPS6040423B2 JP S6040423 B2 JPS6040423 B2 JP S6040423B2 JP 53004769 A JP53004769 A JP 53004769A JP 476978 A JP476978 A JP 476978A JP S6040423 B2 JPS6040423 B2 JP S6040423B2
Authority
JP
Japan
Prior art keywords
formula
compound
acid
item
methylthio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53004769A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5390281A (en
Inventor
ケネス・ジヨ−ジ・ホ−ルデン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPS5390281A publication Critical patent/JPS5390281A/ja
Publication of JPS6040423B2 publication Critical patent/JPS6040423B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP53004769A 1977-01-19 1978-01-18 ユーフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン類 Expired JPS6040423B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19
US760500 2001-01-12

Publications (2)

Publication Number Publication Date
JPS5390281A JPS5390281A (en) 1978-08-08
JPS6040423B2 true JPS6040423B2 (ja) 1985-09-11

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53004769A Expired JPS6040423B2 (ja) 1977-01-19 1978-01-18 ユーフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン類

Country Status (15)

Country Link
JP (1) JPS6040423B2 (sv)
AU (1) AU510459B2 (sv)
BE (1) BE862878A (sv)
CA (1) CA1090334A (sv)
CH (2) CH642634A5 (sv)
DE (1) DE2802086A1 (sv)
DK (1) DK19978A (sv)
FR (2) FR2378017A1 (sv)
GB (2) GB1597912A (sv)
HU (1) HU175836B (sv)
IE (1) IE46761B1 (sv)
LU (1) LU78873A1 (sv)
NL (1) NL7800637A (sv)
SE (1) SE437265B (sv)
ZA (1) ZA777444B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
EP0022330B1 (en) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistic antihypertensive compositions
JP2006526021A (ja) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Also Published As

Publication number Publication date
NL7800637A (nl) 1978-07-21
SE7800455L (sv) 1978-07-20
JPS5390281A (en) 1978-08-08
IE780111L (en) 1978-07-19
SE437265B (sv) 1985-02-18
DE2802086A1 (de) 1978-07-20
DK19978A (da) 1978-07-20
FR2384759B1 (sv) 1980-07-18
BE862878A (fr) 1978-07-13
AU510459B2 (en) 1980-06-26
FR2378017B1 (sv) 1981-07-10
AU3246578A (en) 1979-07-26
LU78873A1 (fr) 1978-06-09
HU175836B (hu) 1980-10-28
IE46761B1 (en) 1983-09-21
FR2378017A1 (fr) 1978-08-18
GB1597912A (en) 1981-09-16
CH642634A5 (en) 1984-04-30
CA1090334A (en) 1980-11-25
GB1597911A (en) 1981-09-16
ZA777444B (en) 1978-10-25
FR2384759A1 (fr) 1978-10-20
CH640228A5 (en) 1983-12-30

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