LU78873A1 - Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,leur procede de preparation et application en therapeutique - Google Patents

Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,leur procede de preparation et application en therapeutique

Info

Publication number
LU78873A1
LU78873A1 LU78873A LU78873A LU78873A1 LU 78873 A1 LU78873 A1 LU 78873A1 LU 78873 A LU78873 A LU 78873A LU 78873 A LU78873 A LU 78873A LU 78873 A1 LU78873 A1 LU 78873A1
Authority
LU
Luxembourg
Prior art keywords
benzazepines
alkylthio
tetrahydro
dihydroxy
phenyl
Prior art date
Application number
LU78873A
Other languages
English (en)
French (fr)
Inventor
K Holden
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of LU78873A1 publication Critical patent/LU78873A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
LU78873A 1977-01-19 1978-01-16 Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,leur procede de preparation et application en therapeutique LU78873A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19

Publications (1)

Publication Number Publication Date
LU78873A1 true LU78873A1 (fr) 1978-06-09

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
LU78873A LU78873A1 (fr) 1977-01-19 1978-01-16 Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,leur procede de preparation et application en therapeutique

Country Status (15)

Country Link
JP (1) JPS6040423B2 (xx)
AU (1) AU510459B2 (xx)
BE (1) BE862878A (xx)
CA (1) CA1090334A (xx)
CH (2) CH642634A5 (xx)
DE (1) DE2802086A1 (xx)
DK (1) DK19978A (xx)
FR (2) FR2378017A1 (xx)
GB (2) GB1597912A (xx)
HU (1) HU175836B (xx)
IE (1) IE46761B1 (xx)
LU (1) LU78873A1 (xx)
NL (1) NL7800637A (xx)
SE (1) SE437265B (xx)
ZA (1) ZA777444B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004794A2 (en) * 1978-04-12 1979-10-17 Smithkline Beckman Corporation Substituted benzazepines, processes for preparing them and pharmaceutical compositions containing them

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
EP0022330B1 (en) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistic antihypertensive compositions
WO2005035504A2 (en) * 2003-05-22 2005-04-21 Schering Corporation 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004794A2 (en) * 1978-04-12 1979-10-17 Smithkline Beckman Corporation Substituted benzazepines, processes for preparing them and pharmaceutical compositions containing them
EP0004794A3 (en) * 1978-04-12 1979-11-14 Smithkline Corporation Substituted benzazepines, processes for preparing them and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2378017A1 (fr) 1978-08-18
AU3246578A (en) 1979-07-26
BE862878A (fr) 1978-07-13
FR2384759B1 (xx) 1980-07-18
CH642634A5 (en) 1984-04-30
IE780111L (en) 1978-07-19
CA1090334A (en) 1980-11-25
NL7800637A (nl) 1978-07-21
JPS5390281A (en) 1978-08-08
GB1597912A (en) 1981-09-16
AU510459B2 (en) 1980-06-26
IE46761B1 (en) 1983-09-21
CH640228A5 (en) 1983-12-30
ZA777444B (en) 1978-10-25
FR2378017B1 (xx) 1981-07-10
GB1597911A (en) 1981-09-16
HU175836B (hu) 1980-10-28
FR2384759A1 (fr) 1978-10-20
SE437265B (sv) 1985-02-18
JPS6040423B2 (ja) 1985-09-11
SE7800455L (sv) 1978-07-20
DK19978A (da) 1978-07-20
DE2802086A1 (de) 1978-07-20

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