JPS5390281A - 11phenyll2*3*4*55tetrahydroo1hh33 benzazepines - Google Patents

11phenyll2*3*4*55tetrahydroo1hh33 benzazepines

Info

Publication number
JPS5390281A
JPS5390281A JP476978A JP476978A JPS5390281A JP S5390281 A JPS5390281 A JP S5390281A JP 476978 A JP476978 A JP 476978A JP 476978 A JP476978 A JP 476978A JP S5390281 A JPS5390281 A JP S5390281A
Authority
JP
Japan
Prior art keywords
11phenyll2
benzazepines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP476978A
Other languages
Japanese (ja)
Other versions
JPS6040423B2 (en
Inventor
Jiyooji Hooruden Kenesu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of JPS5390281A publication Critical patent/JPS5390281A/en
Publication of JPS6040423B2 publication Critical patent/JPS6040423B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP53004769A 1977-01-19 1978-01-18 Euphenyl-2,3,4,5-tetrahydro-1H-3-benzazepines Expired JPS6040423B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19
US760500 1985-07-31

Publications (2)

Publication Number Publication Date
JPS5390281A true JPS5390281A (en) 1978-08-08
JPS6040423B2 JPS6040423B2 (en) 1985-09-11

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53004769A Expired JPS6040423B2 (en) 1977-01-19 1978-01-18 Euphenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

Country Status (15)

Country Link
JP (1) JPS6040423B2 (en)
AU (1) AU510459B2 (en)
BE (1) BE862878A (en)
CA (1) CA1090334A (en)
CH (2) CH642634A5 (en)
DE (1) DE2802086A1 (en)
DK (1) DK19978A (en)
FR (2) FR2378017A1 (en)
GB (2) GB1597912A (en)
HU (1) HU175836B (en)
IE (1) IE46761B1 (en)
LU (1) LU78873A1 (en)
NL (1) NL7800637A (en)
SE (1) SE437265B (en)
ZA (1) ZA777444B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5615207A (en) * 1979-07-10 1981-02-14 Smithkline Corp Antihypertensive composition having synergism
JP2006526021A (en) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 5H-benzo [D] naphtho [2,1-B] azepine derivatives as selective D1 / D5 receptor antagonists to treat obesity and CNS disorders

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (en) * 1967-02-17 1974-11-15 Scherico Ltd 1-Phenyl-tetrahydro-benzazepin derivs - with antibacterial, antidepressive and hypotensive activity, prepd. by ring-closure of di-(beta-phenyl) ethyl amine using dehydrating agents
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5615207A (en) * 1979-07-10 1981-02-14 Smithkline Corp Antihypertensive composition having synergism
JP2006526021A (en) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 5H-benzo [D] naphtho [2,1-B] azepine derivatives as selective D1 / D5 receptor antagonists to treat obesity and CNS disorders

Also Published As

Publication number Publication date
FR2378017A1 (en) 1978-08-18
IE780111L (en) 1978-07-19
BE862878A (en) 1978-07-13
CA1090334A (en) 1980-11-25
SE437265B (en) 1985-02-18
NL7800637A (en) 1978-07-21
HU175836B (en) 1980-10-28
LU78873A1 (en) 1978-06-09
FR2384759B1 (en) 1980-07-18
CH640228A5 (en) 1983-12-30
IE46761B1 (en) 1983-09-21
GB1597911A (en) 1981-09-16
JPS6040423B2 (en) 1985-09-11
AU3246578A (en) 1979-07-26
CH642634A5 (en) 1984-04-30
FR2378017B1 (en) 1981-07-10
SE7800455L (en) 1978-07-20
ZA777444B (en) 1978-10-25
GB1597912A (en) 1981-09-16
AU510459B2 (en) 1980-06-26
FR2384759A1 (en) 1978-10-20
DK19978A (en) 1978-07-20
DE2802086A1 (en) 1978-07-20

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