FR2384759A1 - 1-PHENYL-2,3,4,5 TETRAHYDRO-1H BENZAZEPINE-7,8-DIONES - Google Patents

1-PHENYL-2,3,4,5 TETRAHYDRO-1H BENZAZEPINE-7,8-DIONES

Info

Publication number
FR2384759A1
FR2384759A1 FR7816583A FR7816583A FR2384759A1 FR 2384759 A1 FR2384759 A1 FR 2384759A1 FR 7816583 A FR7816583 A FR 7816583A FR 7816583 A FR7816583 A FR 7816583A FR 2384759 A1 FR2384759 A1 FR 2384759A1
Authority
FR
France
Prior art keywords
benzazepine
diones
tetrahydro
phenyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7816583A
Other languages
French (fr)
Other versions
FR2384759B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2384759A1 publication Critical patent/FR2384759A1/en
Application granted granted Critical
Publication of FR2384759B1 publication Critical patent/FR2384759B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention a pour objet des composés de formule :The subject of the invention is compounds of formula:

FR7816583A 1977-01-19 1978-06-02 1-PHENYL-2,3,4,5 TETRAHYDRO-1H BENZAZEPINE-7,8-DIONES Granted FR2384759A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19

Publications (2)

Publication Number Publication Date
FR2384759A1 true FR2384759A1 (en) 1978-10-20
FR2384759B1 FR2384759B1 (en) 1980-07-18

Family

ID=25059291

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7800998A Granted FR2378017A1 (en) 1977-01-19 1978-01-13 ALKYLTHIO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, THEIR PREPARATION PROCESS AND THERAPEUTIC APPLICATION
FR7816583A Granted FR2384759A1 (en) 1977-01-19 1978-06-02 1-PHENYL-2,3,4,5 TETRAHYDRO-1H BENZAZEPINE-7,8-DIONES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7800998A Granted FR2378017A1 (en) 1977-01-19 1978-01-13 ALKYLTHIO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, THEIR PREPARATION PROCESS AND THERAPEUTIC APPLICATION

Country Status (15)

Country Link
JP (1) JPS6040423B2 (en)
AU (1) AU510459B2 (en)
BE (1) BE862878A (en)
CA (1) CA1090334A (en)
CH (2) CH642634A5 (en)
DE (1) DE2802086A1 (en)
DK (1) DK19978A (en)
FR (2) FR2378017A1 (en)
GB (2) GB1597912A (en)
HU (1) HU175836B (en)
IE (1) IE46761B1 (en)
LU (1) LU78873A1 (en)
NL (1) NL7800637A (en)
SE (1) SE437265B (en)
ZA (1) ZA777444B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020107A1 (en) * 1979-05-25 1980-12-10 Smithkline Beckman Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives, process for preparing them and compositions containing them

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
EP0022330B1 (en) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistic antihypertensive compositions
EP1646623A2 (en) * 2003-05-22 2006-04-19 Schering Corporation 5-h-benzo[d]naphth[2,1-b]azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (en) * 1967-02-17 1974-11-15 Scherico Ltd 1-Phenyl-tetrahydro-benzazepin derivs - with antibacterial, antidepressive and hypotensive activity, prepd. by ring-closure of di-(beta-phenyl) ethyl amine using dehydrating agents
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020107A1 (en) * 1979-05-25 1980-12-10 Smithkline Beckman Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives, process for preparing them and compositions containing them

Also Published As

Publication number Publication date
CA1090334A (en) 1980-11-25
FR2384759B1 (en) 1980-07-18
IE46761B1 (en) 1983-09-21
AU3246578A (en) 1979-07-26
BE862878A (en) 1978-07-13
CH642634A5 (en) 1984-04-30
IE780111L (en) 1978-07-19
ZA777444B (en) 1978-10-25
JPS6040423B2 (en) 1985-09-11
FR2378017A1 (en) 1978-08-18
SE437265B (en) 1985-02-18
DK19978A (en) 1978-07-20
SE7800455L (en) 1978-07-20
JPS5390281A (en) 1978-08-08
CH640228A5 (en) 1983-12-30
FR2378017B1 (en) 1981-07-10
DE2802086A1 (en) 1978-07-20
GB1597912A (en) 1981-09-16
GB1597911A (en) 1981-09-16
LU78873A1 (en) 1978-06-09
AU510459B2 (en) 1980-06-26
HU175836B (en) 1980-10-28
NL7800637A (en) 1978-07-21

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Legal Events

Date Code Title Description
ST Notification of lapse