BE862878A - Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5,-tetrahydro-1h-3-benzazepines, leurs procede de preparation et application en therapeutique - Google Patents

Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5,-tetrahydro-1h-3-benzazepines, leurs procede de preparation et application en therapeutique

Info

Publication number
BE862878A
BE862878A BE184290A BE184290A BE862878A BE 862878 A BE862878 A BE 862878A BE 184290 A BE184290 A BE 184290A BE 184290 A BE184290 A BE 184290A BE 862878 A BE862878 A BE 862878A
Authority
BE
Belgium
Prior art keywords
benzazepines
alkylthio
tetrahydro
dihydroxy
phenyl
Prior art date
Application number
BE184290A
Other languages
English (en)
French (fr)
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of BE862878A publication Critical patent/BE862878A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
BE184290A 1977-01-19 1978-01-13 Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5,-tetrahydro-1h-3-benzazepines, leurs procede de preparation et application en therapeutique BE862878A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19

Publications (1)

Publication Number Publication Date
BE862878A true BE862878A (fr) 1978-07-13

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
BE184290A BE862878A (fr) 1977-01-19 1978-01-13 Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5,-tetrahydro-1h-3-benzazepines, leurs procede de preparation et application en therapeutique

Country Status (15)

Country Link
JP (1) JPS6040423B2 (sv)
AU (1) AU510459B2 (sv)
BE (1) BE862878A (sv)
CA (1) CA1090334A (sv)
CH (2) CH642634A5 (sv)
DE (1) DE2802086A1 (sv)
DK (1) DK19978A (sv)
FR (2) FR2378017A1 (sv)
GB (2) GB1597912A (sv)
HU (1) HU175836B (sv)
IE (1) IE46761B1 (sv)
LU (1) LU78873A1 (sv)
NL (1) NL7800637A (sv)
SE (1) SE437265B (sv)
ZA (1) ZA777444B (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422641A1 (fr) * 1977-11-17 1979-11-09 Smithkline Corp 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
EP0022330B1 (en) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Synergistic antihypertensive compositions
WO2005035504A2 (en) * 2003-05-22 2005-04-21 Schering Corporation 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422641A1 (fr) * 1977-11-17 1979-11-09 Smithkline Corp 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines
EP0026505A1 (en) * 1977-11-17 1981-04-08 Smithkline Beckman Corporation 7,8-Substituted-1-phenyl-2,3,4,5-tetrahydro-1-H-3-benzazepines

Also Published As

Publication number Publication date
FR2378017A1 (fr) 1978-08-18
AU3246578A (en) 1979-07-26
FR2384759B1 (sv) 1980-07-18
CH642634A5 (en) 1984-04-30
IE780111L (en) 1978-07-19
LU78873A1 (fr) 1978-06-09
CA1090334A (en) 1980-11-25
NL7800637A (nl) 1978-07-21
JPS5390281A (en) 1978-08-08
GB1597912A (en) 1981-09-16
AU510459B2 (en) 1980-06-26
IE46761B1 (en) 1983-09-21
CH640228A5 (en) 1983-12-30
ZA777444B (en) 1978-10-25
FR2378017B1 (sv) 1981-07-10
GB1597911A (en) 1981-09-16
HU175836B (hu) 1980-10-28
FR2384759A1 (fr) 1978-10-20
SE437265B (sv) 1985-02-18
JPS6040423B2 (ja) 1985-09-11
SE7800455L (sv) 1978-07-20
DK19978A (da) 1978-07-20
DE2802086A1 (de) 1978-07-20

Similar Documents

Publication Publication Date Title
FR2393795B1 (fr) Derives de carbostyryle, leur procede de preparation et leurs applications en therapeutique
LU80081A1 (fr) Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2383157B1 (fr) Derives de chalcone, leur procede de preparation et leur application en therapeutique
BE875174A (fr) Nouveaux derives de carbostyrile, leur procede de preparation et leurs applications en therapeutique
BE892758A (fr) Derives phenylcyclobutyliques, leur procede de preparation et leur application therapeutique
FR2504920B1 (fr) Derives phenylcyclobutyliques, leur procede de preparation et leur application therapeutique
BE878723A (fr) Derives de 4-anilinoquinazoline, leur procede de preparation et leur application en therapeutique
BE851893A (fr) Nouvelles aryl-3 oxazolidinones-2, leur procede de preparation et leur application en therapeutique
BE854268A (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
FR2458547B2 (fr) Nouvelles n-aryle azolones, leur procede de preparation et leur application en therapeutique
BE862785A (fr) Derives de pyrimido(6,1-a)isoquinoleine-2-one, leur procede de preparation et leur application en therapeutique
FR2349587A1 (fr) 1,3-dihydro-heteroarylspiro(isobenzofurannes), leur procede de preparation et leur application therapeutique
BE845497A (fr) 3-phenylspiro-(isobenzofuranne-1,4'-pipieridine)-sulfenamides, leur procede de preparation et leurs applications
BE868114A (fr) Mercaptoacetylamidobenzoylglycine et procede therapeutique de mucolyse
FR2351965A1 (fr) Benzenesulfonylurees, leur procede de preparation et leur application therapeutique
BE866676A (fr) Derives de bisamidine, leur procede de preparation et leur application therapeutique
FR2313063A1 (fr) Derives de pyrrolotriazolopyrimidine leur procede de preparation et leurs applications en therapeutique
FR2353520A1 (fr) 1-aryloxy-2-hydroxy-3-aminopropanes, leur procede de preparation et leurs applications therapeutiques
BE862878A (fr) Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5,-tetrahydro-1h-3-benzazepines, leurs procede de preparation et application en therapeutique
BE882270A (fr) Derives de benzothiazole, leur procede de preparation et leurs applications en therapeutique
BE866928A (fr) Benzene-sulfonyl urees, leur procede de preparation et leur application therapeutique
PT68267A (fr) Procede de preparation de derives d'oxadiazole-1,2,4 et leur application en therapeutique
FR2351098A1 (fr) Derives de l'isothiouree, leur procede de preparation et leur application therapeutique
BE866648A (fr) Derives de triazolothiadiazines, leur procede de preparation et leurs applications en therapeutique
LU79016A1 (fr) Sels d'imidazole-methylphosphonium,leur procede de preparation et leurs applications

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITHKLINE CORP.

Effective date: 19890131