JPS60260591A - ７‐ハロ‐７‐デオキシリンコマイシン - Google Patents
７‐ハロ‐７‐デオキシリンコマイシンInfo
- Publication number
- JPS60260591A JPS60260591A JP60103616A JP10361685A JPS60260591A JP S60260591 A JPS60260591 A JP S60260591A JP 60103616 A JP60103616 A JP 60103616A JP 10361685 A JP10361685 A JP 10361685A JP S60260591 A JPS60260591 A JP S60260591A
- Authority
- JP
- Japan
- Prior art keywords
- chloride
- lincomycin
- compound
- adduct
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US610364 | 1984-05-15 | ||
| US06/610,364 US4568741A (en) | 1984-05-15 | 1984-05-15 | Synthesis of 7-halo-7-deoxylincomycins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60260591A true JPS60260591A (ja) | 1985-12-23 |
| JPH0533711B2 JPH0533711B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-05-20 |
Family
ID=24444721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60103616A Granted JPS60260591A (ja) | 1984-05-15 | 1985-05-14 | ７‐ハロ‐７‐デオキシリンコマイシン |
Country Status (18)
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1004002B (zh) * | 1984-11-29 | 1989-04-26 | 厄普约翰公司 | 制备7-卤-7-去氧林可霉素及其类似化合物的改进方法 |
| TW282399B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1990-05-25 | 1996-08-01 | Takeda Pharm Industry Co Ltd | |
| DE4039750A1 (de) * | 1990-12-13 | 1992-06-17 | Basf Ag | Verfahren zur entfernung von phosgen aus abgasen |
| JP3202960B2 (ja) | 1998-02-17 | 2001-08-27 | 大塚化学株式会社 | ハロゲン化剤及び水酸基のハロゲン化方法 |
| US6565882B2 (en) * | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
| US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
| US6541014B2 (en) * | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
| US20020068078A1 (en) * | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
| US20020197314A1 (en) * | 2001-02-23 | 2002-12-26 | Rudnic Edward M. | Anti-fungal composition |
| DE60204897T2 (de) * | 2001-08-28 | 2006-05-11 | Pharmacia Corp. | Kristalline freie base von clindamycin |
| US7199105B2 (en) * | 2002-08-15 | 2007-04-03 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antibacterial activity |
| MXPA05001689A (es) * | 2002-08-15 | 2005-05-27 | Vicuron Pharm Inc | Derivados de lincomicina que poseen actividad antibacteriana. |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| JP4828404B2 (ja) | 2003-01-24 | 2011-11-30 | ステフェル リサーチ オーストラリア プロプライエタリー リミティッド | リン酸クリンダマイシン発泡体 |
| US7256177B2 (en) | 2003-06-17 | 2007-08-14 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antibacterial activity |
| US7199106B2 (en) | 2003-06-17 | 2007-04-03 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antimicrobial activity |
| EP1648407A4 (en) * | 2003-07-21 | 2011-08-31 | Middlebrook Pharmaceuticals Inc | ANTIBIOTIC PRODUCT, CORRESPONDING USE AND FORMULATION |
| CA2533358C (en) * | 2003-07-21 | 2014-03-11 | Advancis Pharmaceutical Corporation | Antibiotic product, use and formulation thereof |
| AU2004258949B2 (en) * | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
| WO2005016311A1 (en) | 2003-08-11 | 2005-02-24 | Advancis Pharmaceutical Corporation | Robust pellet |
| WO2005016278A2 (en) * | 2003-08-12 | 2005-02-24 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
| JP5686494B2 (ja) * | 2003-08-29 | 2015-03-18 | シオノギ インコーポレイテッド | 抗生物質製剤、その使用法及び作成方法 |
| US8460710B2 (en) * | 2003-09-15 | 2013-06-11 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
| EP1701705A4 (en) * | 2003-12-24 | 2007-08-08 | Advancis Pharmaceutical Corp | IMPROVED ABSORPTION OF DOSAGE FORMS WITH MODIFIED RELEASE |
| US7361743B2 (en) * | 2004-02-11 | 2008-04-22 | Pfizer Inc | Lincomycin derivatives possessing antibacterial activity |
| WO2006014427A1 (en) * | 2004-07-02 | 2006-02-09 | Advancis Pharmaceutical Corporation | Tablet for pulsed delivery |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| US8778924B2 (en) * | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
| US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
| ES2582654T3 (es) | 2006-03-31 | 2016-09-14 | Stiefel Research Australia Pty Ltd | Gel en suspensión espumable |
| US8299052B2 (en) * | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| GB0620685D0 (en) * | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| CN101205245B (zh) * | 2007-12-06 | 2011-04-06 | 河南天方药业股份有限公司 | 盐酸克林霉素的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496163A (en) * | 1965-02-08 | 1970-02-17 | Upjohn Co | 7-halo-7-deoxylincomycins and process for preparing the same |
| US3435025A (en) * | 1966-03-18 | 1969-03-25 | Upjohn Co | 7-deoxylincomycin and analogs and isomers thereof and process for making the same |
| US3475407A (en) * | 1967-12-22 | 1969-10-28 | Upjohn Co | Process for preparing 7(r)- and 7(s)-halolincomycins |
| US3509127A (en) * | 1968-04-30 | 1970-04-28 | Upjohn Co | Isologs of lincomycins and process for preparing the same |
| US3574186A (en) * | 1969-10-08 | 1971-04-06 | Upjohn Co | Process for making 7-chloro-7-deoxylincomycin and related compounds and novel intermediates produced therein |
| US3714141A (en) * | 1970-05-26 | 1973-01-30 | Upjohn Co | Process for making 7-halolincomycins |
| CA1138443A (en) * | 1979-03-09 | 1982-12-28 | Tate & Lyle Patent Holdings Limited | Process for the preparation of chloro-deoxysugars |
| CN1004002B (zh) * | 1984-11-29 | 1989-04-26 | 厄普约翰公司 | 制备7-卤-7-去氧林可霉素及其类似化合物的改进方法 |
-
1984
- 1984-05-15 US US06/610,364 patent/US4568741A/en not_active Expired - Lifetime
-
1985
- 1985-04-03 CA CA000478286A patent/CA1229592A/en not_active Expired
- 1985-04-04 ZA ZA852592A patent/ZA852592B/xx unknown
- 1985-04-09 AT AT85302494T patent/ATE54150T1/de not_active IP Right Cessation
- 1985-04-09 AU AU40950/85A patent/AU574453B2/en not_active Expired
- 1985-04-09 DE DE8585302494T patent/DE3578425D1/de not_active Expired - Lifetime
- 1985-04-09 EP EP85302494A patent/EP0161794B1/en not_active Expired - Lifetime
- 1985-04-19 IL IL74971A patent/IL74971A/xx not_active IP Right Cessation
- 1985-04-22 MX MX205050A patent/MX163480B/es unknown
- 1985-05-01 DK DK196185A patent/DK166390C/da not_active IP Right Cessation
- 1985-05-08 ES ES542940A patent/ES8606877A1/es not_active Expired
- 1985-05-13 GR GR851150A patent/GR851150B/el unknown
- 1985-05-13 IL IL75175A patent/IL75175A0/xx unknown
- 1985-05-14 JP JP60103616A patent/JPS60260591A/ja active Granted
- 1985-05-14 HU HU851821A patent/HU196820B/hu unknown
- 1985-05-14 PT PT80463A patent/PT80463B/pt unknown
- 1985-05-14 KR KR1019850003279A patent/KR910002224B1/ko not_active Expired
- 1985-05-15 FI FI851941A patent/FI78108C/fi not_active IP Right Cessation
-
1993
- 1993-06-17 HK HK592/93A patent/HK59293A/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
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| SU865125A3 (ru) | Способ получени производных имидазола или их солей | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100520 Year of fee payment: 17 |
|
| EXPY | Cancellation because of completion of term |