JPS6021994B2 - 置換されたチエノベンゼンジアゼピノン、その酸付加塩、その製法及びこれを含有する胃腸薬 - Google Patents

置換されたチエノベンゼンジアゼピノン、その酸付加塩、その製法及びこれを含有する胃腸薬

Info

Publication number
JPS6021994B2
JPS6021994B2 JP56501690A JP50169081A JPS6021994B2 JP S6021994 B2 JPS6021994 B2 JP S6021994B2 JP 56501690 A JP56501690 A JP 56501690A JP 50169081 A JP50169081 A JP 50169081A JP S6021994 B2 JPS6021994 B2 JP S6021994B2
Authority
JP
Japan
Prior art keywords
group
methyl
formula
atom
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56501690A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57500695A (es
Inventor
フイガラ，フオルカー
リーデル，リヒアルト
ライナー，ゲオルク
クレム，クルト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of JPS57500695A publication Critical patent/JPS57500695A/ja
Publication of JPS6021994B2 publication Critical patent/JPS6021994B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP56501690A 1980-05-07 1981-05-06 置換されたチエノベンゼンジアゼピノン、その酸付加塩、その製法及びこれを含有する胃腸薬 Expired JPS6021994B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH3581/80-0 1980-05-07
CH358180 1980-05-07
CH652/81-0 1981-02-02
CH65281 1981-02-02

Publications (2)

Publication Number Publication Date
JPS57500695A JPS57500695A (es) 1982-04-22
JPS6021994B2 true JPS6021994B2 (ja) 1985-05-30

Family

ID=25685262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56501690A Expired JPS6021994B2 (ja) 1980-05-07 1981-05-06 置換されたチエノベンゼンジアゼピノン、その酸付加塩、その製法及びこれを含有する胃腸薬

Country Status (21)

Country Link
EP (1) EP0039519B1 (es)
JP (1) JPS6021994B2 (es)
KR (1) KR850000241B1 (es)
AT (1) ATE7299T1 (es)
AU (1) AU538031B2 (es)
DD (1) DD158902A5 (es)
DE (1) DE3163361D1 (es)
DK (1) DK157872C (es)
ES (1) ES501929A0 (es)
FI (1) FI66002C (es)
GR (1) GR82676B (es)
HK (1) HK6890A (es)
HU (1) HU182712B (es)
IE (1) IE51200B1 (es)
IL (1) IL62792A (es)
NO (1) NO156753C (es)
NZ (1) NZ197017A (es)
PL (1) PL139428B1 (es)
PT (1) PT72982B (es)
WO (1) WO1981003173A1 (es)
YU (1) YU42398B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3204153A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte thienobenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3204169A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte thienobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3529372A1 (de) * 1985-08-16 1987-02-19 Dompe Farmaceutici Spa Aminoacyl-derivat von 4,9-dihydro-10h-pyrido(3,2-b)-thieno(3,2-e) (1,4)-diazepinon und von 4,9-dihydro-10h-pyrido(3,2-b)thieno(3,4-e) (1,4)diazepinon, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5140025A (en) * 1987-12-22 1992-08-18 Byk Gulden Lomberg Chemische Fabrik Gmbh Thienotricylene for the treatment of bronchial diseases
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4003322C1 (es) * 1990-02-05 1991-06-20 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz, De

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1505795A (fr) * 1965-12-17 1967-12-15 Thomae Gmbh Dr K Procédé pour fabriquer de nouvelles 11h-pyrido[2, 3-b][1, 5]benzodiazépine-5(6h)-ones substituées en position 11
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
DE1795176C3 (de) * 1968-08-20 1974-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
DE1931487C3 (de) * 1969-06-20 1975-12-18 Dr. Karl Thomae Gmbh, 7950 Biberach In 5-Stellung substituierte 5,10-Dihydro-11H-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11 -one und Verfahren zu ihrer Herstellung
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SU629879A3 (ru) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
US4172831A (en) * 1974-11-26 1979-10-30 Lilly Industries Limited Thieno-benzodiazepines
US3951981A (en) * 1975-02-24 1976-04-20 American Cyanamid Company Substituted benzodiazepines and method of use
US3953430A (en) * 1975-02-24 1976-04-27 American Cyanamid Company Substituted benzodiazepin-10-ones and method of use
US4144235A (en) * 1978-03-13 1979-03-13 American Cyanamid Company Thieno[3,4-b][1,5]benzoxazepin-10-ones and thieno[3,4-b][1,5]benzothiazepin-10-ones
US4168269A (en) * 1978-04-12 1979-09-18 American Cyanamid Company Substituted thieno-benzodiazepines
US4263207A (en) * 1978-08-01 1981-04-21 Merck & Co., Inc. 10,11-Dihydrodibenzo[b,f][1,4]thiazepine carboxylic acids esters and amides thereof

Also Published As

Publication number Publication date
DE3163361D1 (en) 1984-06-07
AU7019881A (en) 1981-11-12
NO156753B (no) 1987-08-10
PT72982A (en) 1981-06-01
IL62792A0 (en) 1981-07-31
YU116181A (en) 1984-02-29
FI814028L (fi) 1981-12-15
HK6890A (en) 1990-02-02
GR82676B (es) 1985-02-07
DK157872C (da) 1990-07-30
KR830006300A (ko) 1983-09-20
WO1981003173A1 (en) 1981-11-12
EP0039519A1 (de) 1981-11-11
IE810997L (en) 1981-11-07
NZ197017A (en) 1983-09-30
HU182712B (en) 1984-03-28
EP0039519B1 (de) 1984-05-02
NO820025L (no) 1982-01-06
DK157872B (da) 1990-02-26
DD158902A5 (de) 1983-02-09
FI66002C (fi) 1984-08-10
ATE7299T1 (de) 1984-05-15
IE51200B1 (en) 1986-10-29
YU42398B (en) 1988-08-31
PL231003A1 (es) 1981-12-23
JPS57500695A (es) 1982-04-22
PL139428B1 (en) 1987-01-31
NO156753C (no) 1987-11-18
FI66002B (fi) 1984-04-30
AU538031B2 (en) 1984-07-26
ES8205802A1 (es) 1982-08-16
PT72982B (fr) 1982-10-21
DK1582A (da) 1982-01-05
KR850000241B1 (ko) 1985-03-12
IL62792A (en) 1985-02-28
ES501929A0 (es) 1982-08-16

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