JPS55153713A - Pharmaceutical preparation of ribosome containing active substance - Google Patents
Pharmaceutical preparation of ribosome containing active substanceInfo
- Publication number
- JPS55153713A JPS55153713A JP5428379A JP5428379A JPS55153713A JP S55153713 A JPS55153713 A JP S55153713A JP 5428379 A JP5428379 A JP 5428379A JP 5428379 A JP5428379 A JP 5428379A JP S55153713 A JPS55153713 A JP S55153713A
- Authority
- JP
- Japan
- Prior art keywords
- active substance
- ribosome
- wall membrane
- pharmaceutical preparation
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013543 active substance Substances 0.000 title abstract 5
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 210000003934 vacuole Anatomy 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5428379A JPS55153713A (en) | 1979-05-02 | 1979-05-02 | Pharmaceutical preparation of ribosome containing active substance |
| CA000351077A CA1143656A (en) | 1979-05-02 | 1980-05-01 | Liposome including active substance |
| GB8014793A GB2050287B (en) | 1979-05-02 | 1980-05-02 | Liposomes containing physiologically active substances |
| DE19803016976 DE3016976A1 (de) | 1979-05-02 | 1980-05-02 | Liposom mit einem gehalt an einer aktiven substanz und verfahren zu dessen herstellung |
| FR8009985A FR2455458A1 (fr) | 1979-05-02 | 1980-05-05 | Liposomes contenant une substance active, notamment un principe actif de medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5428379A JPS55153713A (en) | 1979-05-02 | 1979-05-02 | Pharmaceutical preparation of ribosome containing active substance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55153713A true JPS55153713A (en) | 1980-11-29 |
| JPH0240644B2 JPH0240644B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-09-12 |
Family
ID=12966226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5428379A Granted JPS55153713A (en) | 1979-05-02 | 1979-05-02 | Pharmaceutical preparation of ribosome containing active substance |
Country Status (5)
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60152410A (ja) * | 1984-01-23 | 1985-08-10 | Pola Chem Ind Inc | 皮膚外用剤 |
| JPS60243022A (ja) * | 1984-04-09 | 1985-12-03 | サンド・アクチエンゲゼルシヤフト | インタ−リユ−キン療法に関する改良 |
| JPS61100518A (ja) * | 1984-10-22 | 1986-05-19 | Ono Pharmaceut Co Ltd | ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤 |
| WO2005053643A1 (ja) * | 2003-12-01 | 2005-06-16 | Mitsubishi Pharma Corporation | リポソーム |
| JP2015514683A (ja) * | 2012-02-16 | 2015-05-21 | ブライトサイド イノベーションズ,インコーポレイティド | 食品性栄養組成物および使用方法 |
| WO2017057418A1 (ja) * | 2015-09-28 | 2017-04-06 | 小林製薬株式会社 | リポソーム |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692433A (en) * | 1983-10-12 | 1987-09-08 | The Regents Of The University Of California | Method and composition for regulating serum calcium levels of mammals |
| GB8428222D0 (en) * | 1984-11-08 | 1984-12-19 | Bentall R H C | Quantifying interaction of induced currents |
| US5023087A (en) * | 1986-02-10 | 1991-06-11 | Liposome Technology, Inc. | Efficient method for preparation of prolonged release liposome-based drug delivery system |
| US4849227A (en) * | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| NO177774C (no) * | 1987-01-27 | 1995-11-22 | Vestar Inc | Fremgangsmåte for fremstilling av et preparat egnet for tilförsel av en hovedsakelig vannuopplöslig aktiv bestanddel |
| US5723147A (en) * | 1987-02-23 | 1998-03-03 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
| US5811119A (en) * | 1987-05-19 | 1998-09-22 | Board Of Regents, The University Of Texas | Formulation and use of carotenoids in treatment of cancer |
| US5925375A (en) * | 1987-05-22 | 1999-07-20 | The Liposome Company, Inc. | Therapeutic use of multilamellar liposomal prostaglandin formulations |
| US5811118A (en) * | 1987-05-22 | 1998-09-22 | The Liposome Company, Inc. | Methods of treatment using unilamellar liposomal arachidonic acid metabolite formulations |
| US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
| WO1988009170A1 (en) * | 1987-05-22 | 1988-12-01 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
| SE457933B (sv) * | 1987-07-06 | 1989-02-13 | Larsson Kare | Farmaceutisk komposition innefattande en vattendispergerad blandning av lipider, monoglycerider och fosfatidylkolin samt dess anvaendning foer framstaellning av en gastronintestinalt verksam kompostion |
| US5807572A (en) * | 1988-02-18 | 1998-09-15 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
| US5422120A (en) * | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
| GB8822857D0 (en) * | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
| FR2649610B1 (fr) * | 1989-07-13 | 1994-06-03 | Dior Christian Parfums | Composition cosmetique ou pharmaceutique et notamment dermatologique contenant de l'ampc ou ses derives en liposomes |
| DE4005711C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1990-02-23 | 1991-06-13 | A. Nattermann & Cie Gmbh, 5000 Koeln, De | |
| DE4108902A1 (de) * | 1990-08-06 | 1992-02-13 | Nattermann A & Cie | Wasserhaltiges liposomensystem |
| US5556637A (en) * | 1990-08-06 | 1996-09-17 | A. Nattermann & Cie. Gmbh | Water containing liposome system |
| DE4107152C2 (de) * | 1991-03-06 | 1994-03-24 | Gregor Cevc | Präparate zur nichtinvasiven Verabreichung von Antidiabetica |
| DE4107153A1 (de) * | 1991-03-06 | 1992-09-10 | Gregor Cevc | Praeparat zur wirkstoffapplikation in kleinsttroepfchenform |
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| WO1995001163A1 (fr) * | 1992-01-03 | 1995-01-12 | Corbiere Jerome | Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale |
| FR2685868B1 (fr) * | 1992-01-03 | 1995-06-23 | Corbiere Jerome | Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale. |
| ES2128417T3 (es) * | 1992-01-16 | 1999-05-16 | Univ Texas | Formulacion y utilizacion de carotenoides en el tratamiento del cancer. |
| IL101241A (en) * | 1992-03-16 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier |
| US5989587A (en) * | 1992-10-23 | 1999-11-23 | National Research Council Of Canada | Formation of stable liposomes from lipid extracts of archaeobacteria (archaeu) |
| JPH0657741U (ja) * | 1993-01-22 | 1994-08-12 | 株式会社村上開明堂 | 監視機能付きミラー装置 |
| US5455044A (en) * | 1993-05-14 | 1995-10-03 | Depotech Corporation | Method for treating neurological disorders |
| US5853755A (en) * | 1993-07-28 | 1998-12-29 | Pharmaderm Laboratories Ltd. | Biphasic multilamellar lipid vesicles |
| IL107471A (en) * | 1993-11-02 | 1997-09-30 | Yissum Res Dev Co | Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production |
| RO116341B1 (ro) * | 1993-11-16 | 2001-01-30 | Depotech Corp La Jolia | Lipozom multivezicular si procedeu de obtinere a acestuia |
| US5840328A (en) * | 1994-01-11 | 1998-11-24 | The Liposome Company, Inc. | Treatment using arachidonic acid metabolite and particulate formulations |
| WO1996004891A1 (en) * | 1994-08-08 | 1996-02-22 | Board Of Regents, The University Of Texas System | Formulation and use of carotenoids in treatment of cancer |
| US5993850A (en) * | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
| US5965160A (en) * | 1995-04-24 | 1999-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsifiable formulation producing an oil-in-water emulsion |
| US5931809A (en) * | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| IL117773A (en) * | 1996-04-02 | 2000-10-31 | Pharmos Ltd | Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability |
| US5997899A (en) | 1996-10-01 | 1999-12-07 | Skyepharma Inc. | Method for producing liposomes with increased percent of compound encapsulated |
| WO1999002139A1 (en) * | 1997-07-10 | 1999-01-21 | Keith Baker | Methods for universally distributing therapeutic agents to the brain |
| US6306432B1 (en) | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
| ES2343767T3 (es) | 1997-09-18 | 2010-08-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestesicas liposomicas de liberacion sostenida. |
| WO1999025319A1 (en) | 1997-11-14 | 1999-05-27 | Depotech Corporation | Production of multivesicular liposomes |
| KR100638150B1 (ko) | 1998-12-23 | 2006-10-26 | 이데아 악티엔게젤샤프트 | 생체내에서 국부적인 비침습성 용도로 사용되는 개선된 제제 |
| PT1031347E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
| EP1031346B1 (en) | 1999-01-27 | 2002-05-02 | Idea Ag | Noninvasive vaccination through the skin |
| AU5409699A (en) | 1999-07-05 | 2001-01-22 | Idea Ag | A method for the improvement of transport across adaptable semi-permeable barriers |
| US20030068361A1 (en) * | 2001-10-09 | 2003-04-10 | Rimona Margalit | Liposome-encapsulated insulin formulations |
| US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| EP2585046A4 (en) * | 2010-06-23 | 2013-11-06 | Brightside Innovations Inc | LECITHINTRÄGERVESIKEL AND METHOD FOR THE PRODUCTION THEREOF |
| CN110536674A (zh) * | 2017-05-23 | 2019-12-03 | 大江生医股份有限公司 | 乳化脂质体组合物及其制备方法 |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12285419B2 (en) | 2021-10-14 | 2025-04-29 | Pacira Pharmaceuticals, Inc. | Bupivacaine multivesicular liposome formulations and uses thereof |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12156940B1 (en) | 2024-05-20 | 2024-12-03 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12251468B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS49118826A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1971-10-12 | 1974-11-13 | ||
| JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
| JPS5513260A (en) * | 1978-04-14 | 1980-01-30 | Little Inc A | Xenobiotics transfer vehicles*their production and use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3060030A (en) * | 1960-04-04 | 1962-10-23 | Carl F Obenauf | Lecithinated product |
| JPS5126213A (ja) * | 1974-08-21 | 1976-03-04 | Tanabe Seiyaku Co | Johoseibiryushiseizaino seiho |
| GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
-
1979
- 1979-05-02 JP JP5428379A patent/JPS55153713A/ja active Granted
-
1980
- 1980-05-01 CA CA000351077A patent/CA1143656A/en not_active Expired
- 1980-05-02 DE DE19803016976 patent/DE3016976A1/de not_active Ceased
- 1980-05-02 GB GB8014793A patent/GB2050287B/en not_active Expired
- 1980-05-05 FR FR8009985A patent/FR2455458A1/fr active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS49118826A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1971-10-12 | 1974-11-13 | ||
| JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
| JPS5513260A (en) * | 1978-04-14 | 1980-01-30 | Little Inc A | Xenobiotics transfer vehicles*their production and use |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60152410A (ja) * | 1984-01-23 | 1985-08-10 | Pola Chem Ind Inc | 皮膚外用剤 |
| JPS60243022A (ja) * | 1984-04-09 | 1985-12-03 | サンド・アクチエンゲゼルシヤフト | インタ−リユ−キン療法に関する改良 |
| JPS61100518A (ja) * | 1984-10-22 | 1986-05-19 | Ono Pharmaceut Co Ltd | ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤 |
| WO2005053643A1 (ja) * | 2003-12-01 | 2005-06-16 | Mitsubishi Pharma Corporation | リポソーム |
| JP2015514683A (ja) * | 2012-02-16 | 2015-05-21 | ブライトサイド イノベーションズ,インコーポレイティド | 食品性栄養組成物および使用方法 |
| US10888572B2 (en) | 2012-02-16 | 2021-01-12 | Bio-Up Mimetic Technologies, Inc. | Dietary and nutritional compositions and methods of use |
| WO2017057418A1 (ja) * | 2015-09-28 | 2017-04-06 | 小林製薬株式会社 | リポソーム |
| JP2017066059A (ja) * | 2015-09-28 | 2017-04-06 | 小林製薬株式会社 | リポソーム |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2050287A (en) | 1981-01-07 |
| CA1143656A (en) | 1983-03-29 |
| JPH0240644B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-09-12 |
| DE3016976A1 (de) | 1980-11-13 |
| FR2455458A1 (fr) | 1980-11-28 |
| FR2455458B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1983-04-15 |
| GB2050287B (en) | 1983-04-20 |
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