JPS5432460A - Cycloalkylidenemethylphenylacetic acid derivative and their preparation - Google Patents

Cycloalkylidenemethylphenylacetic acid derivative and their preparation

Info

Publication number
JPS5432460A
JPS5432460A JP9812177A JP9812177A JPS5432460A JP S5432460 A JPS5432460 A JP S5432460A JP 9812177 A JP9812177 A JP 9812177A JP 9812177 A JP9812177 A JP 9812177A JP S5432460 A JPS5432460 A JP S5432460A
Authority
JP
Japan
Prior art keywords
preparation
acid derivative
cycloalkylidenemethylphenylacetic
cycloalkylidenemethylphenylacetic acid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9812177A
Other languages
English (en)
Other versions
JPS5757019B2 (ja
Inventor
Atsusuke Terada
Shigeru Tanaka
Hidekazu Mitsusaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP9812177A priority Critical patent/JPS5432460A/ja
Priority to US05/929,937 priority patent/US4254274A/en
Priority to GB7832509A priority patent/GB2002762B/en
Priority to BE78189875A priority patent/BE869721A/xx
Priority to CA309,215A priority patent/CA1113114A/en
Priority to DK360278A priority patent/DK151251C/da
Priority to CH866578A priority patent/CH636839A5/de
Priority to FR7823871A priority patent/FR2400500A1/fr
Priority to IT68914/78A priority patent/IT1118095B/it
Priority to MX787315U priority patent/MX5149E/es
Priority to DE2835701A priority patent/DE2835701C2/de
Priority to ES472588A priority patent/ES472588A1/es
Priority to NLAANVRAGE7808503,A priority patent/NL189561C/xx
Priority to MX1041578U priority patent/MX7006E/es
Publication of JPS5432460A publication Critical patent/JPS5432460A/ja
Priority to ES487769A priority patent/ES487769A1/es
Priority to US06/197,229 priority patent/US4365076A/en
Publication of JPS5757019B2 publication Critical patent/JPS5757019B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP9812177A 1977-08-16 1977-08-16 Cycloalkylidenemethylphenylacetic acid derivative and their preparation Granted JPS5432460A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP9812177A JPS5432460A (en) 1977-08-16 1977-08-16 Cycloalkylidenemethylphenylacetic acid derivative and their preparation
US05/929,937 US4254274A (en) 1977-08-16 1978-08-01 Cycloalkylidenemethylphenylacetic acid derivatives and process for the preparation thereof
GB7832509A GB2002762B (en) 1977-08-16 1978-08-07 Cycloalkylidenemethylphenylacetic acid derivatives
BE78189875A BE869721A (fr) 1977-08-16 1978-08-11 Derives d'acides cycloalcoylindenemethylphenylacetiques, leur procede de preparation et leur application en therapeutique
CA309,215A CA1113114A (en) 1977-08-16 1978-08-11 Cycloalkylidenemethylphenylacetic acid derivatives
DK360278A DK151251C (da) 1977-08-16 1978-08-15 Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive 2-(4-(cycloalkylidenmethyl)-phenyl)propionsyrederivater eller farmaceutisk acceptable salte deraf
CH866578A CH636839A5 (de) 1977-08-16 1978-08-15 4-(2-oxo-1-cycloalkylidenmethyl)-phenylessigsaeurederivate, sowie verfahren zu deren herstellung und pharmazeutisch zulaessige salze solcher verbindungen.
MX787315U MX5149E (es) 1977-08-16 1978-08-16 Procedimiento mejorado para la preparacion de derivados de acido cicloalquilidenmetilfenilacetico
IT68914/78A IT1118095B (it) 1977-08-16 1978-08-16 Derivati dell acido cicloalchiliden metilfenilacetico particolarmente utili come medicamenti e procedimento per la loro preparazione
FR7823871A FR2400500A1 (fr) 1977-08-16 1978-08-16 Derives d'acides cycloalcoylidenemethylphenylacetiques, leur procede de preparation et leur application en therapeutique
DE2835701A DE2835701C2 (de) 1977-08-16 1978-08-16 Cycloalkylidenmethylphenylessigsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
ES472588A ES472588A1 (es) 1977-08-16 1978-08-16 Un procedimiento para la preparacion de un nuevo derivado deacido cicloalquilidenmetilfenilacetico
NLAANVRAGE7808503,A NL189561C (nl) 1977-08-16 1978-08-16 Gesubstitueerde cyclo-alkylideenmethylfenylazijnzuurverbindingen, alsmede een farmaceutisch preparaat, dat deze verbindingen bevat.
MX1041578U MX7006E (es) 1977-08-16 1978-08-16 Procedimiento mejorado para la preparacion de derivados de acido cicloalquiliden metilfenilacetico
ES487769A ES487769A1 (es) 1977-08-16 1980-01-16 Un procedimiento para la preparacion de un nuevo derivado de acido cicloalquilidenmetilfenilacetico
US06/197,229 US4365076A (en) 1977-08-16 1980-10-14 Process for the preparation of cycloalkylidenemethylphenylacetic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9812177A JPS5432460A (en) 1977-08-16 1977-08-16 Cycloalkylidenemethylphenylacetic acid derivative and their preparation

Publications (2)

Publication Number Publication Date
JPS5432460A true JPS5432460A (en) 1979-03-09
JPS5757019B2 JPS5757019B2 (ja) 1982-12-02

Family

ID=14211452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9812177A Granted JPS5432460A (en) 1977-08-16 1977-08-16 Cycloalkylidenemethylphenylacetic acid derivative and their preparation

Country Status (13)

Country Link
US (2) US4254274A (ja)
JP (1) JPS5432460A (ja)
BE (1) BE869721A (ja)
CA (1) CA1113114A (ja)
CH (1) CH636839A5 (ja)
DE (1) DE2835701C2 (ja)
DK (1) DK151251C (ja)
ES (2) ES472588A1 (ja)
FR (1) FR2400500A1 (ja)
GB (1) GB2002762B (ja)
IT (1) IT1118095B (ja)
MX (1) MX5149E (ja)
NL (1) NL189561C (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS574919A (en) * 1980-06-09 1982-01-11 Sankyo Co Ltd Anti-inflammatory for external use
JPS57103950A (en) * 1980-12-19 1982-06-28 Nok Corp Belt with special profile and manufacture of the same
JPS58105939A (ja) * 1981-12-18 1983-06-24 Sankyo Co Ltd 置換フエニル酢酸誘導体及びその製法
JPH08116881A (ja) * 1994-10-26 1996-05-14 Yutaka Koizumi 茶葉の微粉化方法、それにより得られる超微粉末茶ならびにそれを用いた茶飲料および飲食物
US9006294B2 (en) 2008-11-12 2015-04-14 Daewon Pharm., Co., Ltd. Oral pharmaceutical formulation of pelubiprofen with improved dissolution rate and stability

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH645539A5 (de) * 1980-06-09 1984-10-15 Sankyo Co Antiinflammatorische mittel fuer die aeusserliche anwendung.
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
JPS6122043A (ja) * 1984-07-10 1986-01-30 Sankyo Co Ltd シクロアルキリデンメチルフエニル酢酸誘導体の製法
US5244920A (en) * 1985-04-15 1993-09-14 Schering Spa Pharmaceutical compositions having therapeutical activity based on mercaptoethansulphonic arginine salt
IT1185551B (it) * 1985-04-15 1987-11-12 Schering Spa Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione
KR100501993B1 (ko) * 1998-11-20 2005-10-26 주식회사 코오롱 페닐프로피온산 유도체 또는 그의 염의 제조방법
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
US6392053B2 (en) * 1999-12-15 2002-05-21 Bristol-Myers Squibb Company Process for preparing arylacetylaminothiazoles
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
TW200827343A (en) 2006-09-11 2008-07-01 Fuji Yakuhin Co Ltd Novel phenylacetic acid derivative
CN106316837B (zh) * 2015-06-24 2020-04-24 浙江九洲药业股份有限公司 一种取代苯乙酸衍生物的制备方法
CN106699559B (zh) * 2015-11-12 2021-04-06 浙江九洲药业股份有限公司 一种洛索洛芬钠的制备工艺
KR20200069617A (ko) 2018-12-07 2020-06-17 엠에프씨 주식회사 플루비프로펜의 제조방법
KR20220039116A (ko) 2020-09-21 2022-03-29 엠에프씨 주식회사 고순도 펠루비프로펜의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729509A (en) * 1970-04-20 1973-04-24 Merck & Co Inc (mono-and diacylvinyl)aryl alkanoic(and alkenoic)acids
JPS5740132B2 (ja) * 1975-02-19 1982-08-25

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS574919A (en) * 1980-06-09 1982-01-11 Sankyo Co Ltd Anti-inflammatory for external use
JPS57103950A (en) * 1980-12-19 1982-06-28 Nok Corp Belt with special profile and manufacture of the same
JPS6260327B2 (ja) * 1980-12-19 1987-12-16 Nok Corp
JPS58105939A (ja) * 1981-12-18 1983-06-24 Sankyo Co Ltd 置換フエニル酢酸誘導体及びその製法
JPH0219815B2 (ja) * 1981-12-18 1990-05-07 Sankyo Co
JPH08116881A (ja) * 1994-10-26 1996-05-14 Yutaka Koizumi 茶葉の微粉化方法、それにより得られる超微粉末茶ならびにそれを用いた茶飲料および飲食物
US9006294B2 (en) 2008-11-12 2015-04-14 Daewon Pharm., Co., Ltd. Oral pharmaceutical formulation of pelubiprofen with improved dissolution rate and stability

Also Published As

Publication number Publication date
BE869721A (fr) 1979-02-12
ES487769A1 (es) 1980-10-01
US4254274A (en) 1981-03-03
IT7868914A0 (it) 1978-08-16
ES472588A1 (es) 1980-04-16
US4365076A (en) 1982-12-21
IT1118095B (it) 1986-02-24
DK151251C (da) 1988-05-09
DE2835701C2 (de) 1986-12-11
GB2002762A (en) 1979-02-28
FR2400500A1 (fr) 1979-03-16
DE2835701A1 (de) 1979-03-01
NL7808503A (nl) 1979-02-20
JPS5757019B2 (ja) 1982-12-02
GB2002762B (en) 1982-04-07
CH636839A5 (de) 1983-06-30
DK151251B (da) 1987-11-16
DK360278A (da) 1979-02-17
MX5149E (es) 1983-04-04
NL189561C (nl) 1993-05-17
CA1113114A (en) 1981-11-24
NL189561B (nl) 1992-12-16
FR2400500B1 (ja) 1983-10-28

Similar Documents

Publication Publication Date Title
JPS5432460A (en) Cycloalkylidenemethylphenylacetic acid derivative and their preparation
JPS5297950A (en) Chalconeether derivatives
JPS5395912A (en) New derivative of active acetic acid ulceratives
JPS53111033A (en) 4-phenyl-4-oxolactic acid derivatives and their preparation
JPS5427578A (en) 1-carboxyalkylcarbamoyl-5-fluorouracil derivatives and their preparation
JPS5321170A (en) Preparation of branched 2-deoxy-alpha-glycosides
JPS5414992A (en) Novel cyclopropylmethylamine derivative and its preparation
JPS5414961A (en) Novel 3-hydroxyazetidine-3-carboxylic derivative
JPS5430172A (en) Pyrazolidine derivative
JPS5359656A (en) Silacyclopropene derivatives and process for preparation of the same
JPS5416466A (en) Novel 3-hydroxypyrrolldine-3-carboxylic derivative
JPS53101308A (en) Derivative of 5,6-dihydro-2h-pyran and its preparation
JPS5262295A (en) Preparation of n1-oxy-2-thioadenosines
JPS52102280A (en) 5,7,8-trimethyltocotrienol-nicotinic acid esters and preparation there of
JPS5439017A (en) Novel organic sulfonic acid esters and their preparation
JPS51148025A (en) Insecticides, miticides and their preparation
JPS545924A (en) Derivative of butylaldeyde and its preparation
JPS5368777A (en) Preparation of phenyathridine
JPS5387330A (en) Novel thiohydroxymate derivative, its preparation and bactericideand herbicide containing the same
JPS5439080A (en) Isoquinolinoacetic acids
JPS5432463A (en) 5-oxoalkyl-2-furancarboxylic acid esters and their preparation
JPS545952A (en) Alkyphenethyldichlorosilanes and process for their preparation
JPS543021A (en) Novel derivative of glutamic acid and its preparation
JPS5430141A (en) Novel benzoylphenoxyacetic acid derivatives
JPS5242884A (en) Preparation of 2,3,6-trimethyl hydroquinone-1-nicotinic acid esters