IT1185551B - Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione - Google Patents

Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione

Info

Publication number
IT1185551B
IT1185551B IT20338/85A IT2033885A IT1185551B IT 1185551 B IT1185551 B IT 1185551B IT 20338/85 A IT20338/85 A IT 20338/85A IT 2033885 A IT2033885 A IT 2033885A IT 1185551 B IT1185551 B IT 1185551B
Authority
IT
Italy
Prior art keywords
acid
mercaptoethane
ethan
mercapto
derivatives
Prior art date
Application number
IT20338/85A
Other languages
English (en)
Other versions
IT8520338A0 (it
Inventor
Alberto Reiner
Giuseppe Vita
Original Assignee
Schering Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Spa filed Critical Schering Spa
Priority to IT20338/85A priority Critical patent/IT1185551B/it
Publication of IT8520338A0 publication Critical patent/IT8520338A0/it
Priority to AT86200597T priority patent/ATE59554T1/de
Priority to DE8686200597T priority patent/DE3676335D1/de
Priority to EP86200597A priority patent/EP0198542B1/en
Priority to JP61086967A priority patent/JP2553838B2/ja
Application granted granted Critical
Publication of IT1185551B publication Critical patent/IT1185551B/it
Priority to US07/348,171 priority patent/US5019596A/en
Priority to US07/960,216 priority patent/US5244920A/en
Priority to JP8071084A priority patent/JP2611949B2/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
IT20338/85A 1985-04-15 1985-04-15 Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione IT1185551B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT20338/85A IT1185551B (it) 1985-04-15 1985-04-15 Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione
AT86200597T ATE59554T1 (de) 1985-04-15 1986-04-09 Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung.
DE8686200597T DE3676335D1 (de) 1985-04-15 1986-04-09 Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung.
EP86200597A EP0198542B1 (en) 1985-04-15 1986-04-09 Pharmaceutical compositions having therapeutical activity based on mercaptoethansulphonic acid, organic saline derivatives of the mercaptoethansulphonic acid useful for these compositions, and related process for their preparation
JP61086967A JP2553838B2 (ja) 1985-04-15 1986-04-15 医薬組成物
US07/348,171 US5019596A (en) 1985-04-15 1989-05-02 Pharmaceutical compositions having therapeutical activity based on mercaptoethansulphonic acid
US07/960,216 US5244920A (en) 1985-04-15 1992-10-13 Pharmaceutical compositions having therapeutical activity based on mercaptoethansulphonic arginine salt
JP8071084A JP2611949B2 (ja) 1985-04-15 1996-02-28 メルカプトエタンスルホン酸誘導体及びその製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20338/85A IT1185551B (it) 1985-04-15 1985-04-15 Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione

Publications (2)

Publication Number Publication Date
IT8520338A0 IT8520338A0 (it) 1985-04-15
IT1185551B true IT1185551B (it) 1987-11-12

Family

ID=11165844

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20338/85A IT1185551B (it) 1985-04-15 1985-04-15 Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione

Country Status (6)

Country Link
US (1) US5019596A (it)
EP (1) EP0198542B1 (it)
JP (2) JP2553838B2 (it)
AT (1) ATE59554T1 (it)
DE (1) DE3676335D1 (it)
IT (1) IT1185551B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1197490B (it) * 1986-10-08 1988-11-30 Schering Spa Procedimento per la preparazione di derivati salini dell'acido mercaptoetansolfonico
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
DE4122167A1 (de) * 1990-07-16 1992-01-23 Asta Pharma Ag Tablette und granulat enthaltend als wirkstoff mesna
ES2111659T3 (es) * 1992-03-11 1998-03-16 Asta Medica Ag Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion.
DE4233842A1 (de) * 1992-10-08 1994-04-14 Asta Medica Ag Mesna Injektionslösungen
CA2362787A1 (en) * 1999-02-16 2000-08-24 Rutgers, The State University Novel redox clamping agents and uses thereof
US20030036513A1 (en) * 1999-02-16 2003-02-20 Yurkow Edward J. Method for treating cancer
IL156374A0 (en) * 2003-06-10 2004-01-04 Danenberg Holdings 2000 Ltd N Method for removing a pigmented section of skin
IL157696A0 (en) * 2003-09-01 2004-03-28 Hawk Medical Technologies Ltd Apparatus and method for removing a pigmented section of skin
US7282602B2 (en) * 2004-09-21 2007-10-16 Bionumerik Pharmaceuticals, Inc. Medicinal disulfide salts
CN101232858B (zh) * 2005-08-01 2011-08-24 华克医药科技有限公司 根除色素沉着和疤痕组织的方法和装置
US8916609B2 (en) 2011-06-10 2014-12-23 New York University Compounds as L-cystine crystallization inhibitors and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1072516A (fr) * 1951-12-12 1954-09-14 Unilever Nv Perfectionnements relatifs aux alcanesulfonates et à leur préparation
US2695310A (en) * 1951-12-12 1954-11-23 Lever Brothers Ltd Preparation of guanidinium mercaptoalkanesulfonate
US2694723A (en) * 1952-09-27 1954-11-16 Lever Brothers Ltd Xanthogenato-sulfonates and process for the preparation of mercaptoalkanesulfonates
GB1119721A (en) * 1965-05-07 1968-07-10 Ucb Sa Mucolytic mercapto-sulphonates
US4105789A (en) * 1976-05-10 1978-08-08 E. R. Squibb & Sons, Inc. Carboxyalkylacylamino acids
JPS5432460A (en) * 1977-08-16 1979-03-09 Sankyo Co Ltd Cycloalkylidenemethylphenylacetic acid derivative and their preparation
EP0002495B1 (de) * 1977-12-14 1984-02-15 Asta-Werke Aktiengesellschaft Chemische Fabrik Erzeugnisse zur Anwendung in der cytostatischen Therapie
DE2806866C3 (de) * 1978-02-17 1981-02-12 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld Verwendung von Salzen von Dithiodialkansulfonsäuren
DE3022599A1 (de) * 1979-06-18 1981-01-08 Glaxo Group Ltd Alkansaeurederivate
US4418206A (en) * 1982-03-22 1983-11-29 Syntex (U.S.A.) Inc. 9-Deoxy-9-methylene derivatives of (dl)-16-phenoxy and 16-phenoxy substituted prostatriene compounds
US4503072A (en) * 1982-12-22 1985-03-05 Merck & Co., Inc. Antihypercholesterolemic compounds

Also Published As

Publication number Publication date
DE3676335D1 (de) 1991-02-07
ATE59554T1 (de) 1991-01-15
JPH08277262A (ja) 1996-10-22
US5019596A (en) 1991-05-28
EP0198542B1 (en) 1991-01-02
IT8520338A0 (it) 1985-04-15
JPS61238722A (ja) 1986-10-24
EP0198542A1 (en) 1986-10-22
JP2553838B2 (ja) 1996-11-13
JP2611949B2 (ja) 1997-05-21

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970506