ATE59554T1 - Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung. - Google Patents

Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung.

Info

Publication number
ATE59554T1
ATE59554T1 AT86200597T AT86200597T ATE59554T1 AT E59554 T1 ATE59554 T1 AT E59554T1 AT 86200597 T AT86200597 T AT 86200597T AT 86200597 T AT86200597 T AT 86200597T AT E59554 T1 ATE59554 T1 AT E59554T1
Authority
AT
Austria
Prior art keywords
mercaptoethanesulphonic
acids
derivatives
processes
preparation
Prior art date
Application number
AT86200597T
Other languages
English (en)
Inventor
Alberto Reiner
Giuseppe Vita
Original Assignee
Schering Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Spa filed Critical Schering Spa
Application granted granted Critical
Publication of ATE59554T1 publication Critical patent/ATE59554T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
AT86200597T 1985-04-15 1986-04-09 Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung. ATE59554T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20338/85A IT1185551B (it) 1985-04-15 1985-04-15 Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione
EP86200597A EP0198542B1 (de) 1985-04-15 1986-04-09 Auf Mercaptoethansulfonsäuren basierende pharmazeutische Zusammensetzungen, organische Abkömmlinge von Mercaptoethansulfonsäuren sowie Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ATE59554T1 true ATE59554T1 (de) 1991-01-15

Family

ID=11165844

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86200597T ATE59554T1 (de) 1985-04-15 1986-04-09 Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung.

Country Status (6)

Country Link
US (1) US5019596A (de)
EP (1) EP0198542B1 (de)
JP (2) JP2553838B2 (de)
AT (1) ATE59554T1 (de)
DE (1) DE3676335D1 (de)
IT (1) IT1185551B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1197490B (it) * 1986-10-08 1988-11-30 Schering Spa Procedimento per la preparazione di derivati salini dell'acido mercaptoetansolfonico
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
DK0468245T3 (da) * 1990-07-16 1994-05-16 Asta Medica Ag Tablet og granulat indeholdende mesna som aktivt middel
EP0560092B1 (de) * 1992-03-11 1997-12-03 ASTA Medica Aktiengesellschaft Tabletten, Granulate und Pellets mit hohem Gehalt an Wirkstoffen für hochkonzentrierte, feste Darreichungsformen
DE4233842A1 (de) * 1992-10-08 1994-04-14 Asta Medica Ag Mesna Injektionslösungen
WO2000048632A1 (en) * 1999-02-16 2000-08-24 Rutgers, The State University Novel redox clamping agents and uses thereof
US20030036513A1 (en) * 1999-02-16 2003-02-20 Yurkow Edward J. Method for treating cancer
IL156374A0 (en) * 2003-06-10 2004-01-04 Danenberg Holdings 2000 Ltd N Method for removing a pigmented section of skin
IL157696A0 (en) * 2003-09-01 2004-03-28 Hawk Medical Technologies Ltd Apparatus and method for removing a pigmented section of skin
US7282602B2 (en) * 2004-09-21 2007-10-16 Bionumerik Pharmaceuticals, Inc. Medicinal disulfide salts
ES2466646T3 (es) * 2005-08-01 2014-06-10 Hawk Medical Technologies Ltd. Erradicación de pigmentación y tejido cicatrizal
US8916609B2 (en) 2011-06-10 2014-12-23 New York University Compounds as L-cystine crystallization inhibitors and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2695310A (en) * 1951-12-12 1954-11-23 Lever Brothers Ltd Preparation of guanidinium mercaptoalkanesulfonate
FR1072516A (fr) * 1951-12-12 1954-09-14 Unilever Nv Perfectionnements relatifs aux alcanesulfonates et à leur préparation
US2694723A (en) * 1952-09-27 1954-11-16 Lever Brothers Ltd Xanthogenato-sulfonates and process for the preparation of mercaptoalkanesulfonates
GB1119721A (en) * 1965-05-07 1968-07-10 Ucb Sa Mucolytic mercapto-sulphonates
US4105789A (en) * 1976-05-10 1978-08-08 E. R. Squibb & Sons, Inc. Carboxyalkylacylamino acids
JPS5432460A (en) * 1977-08-16 1979-03-09 Sankyo Co Ltd Cycloalkylidenemethylphenylacetic acid derivative and their preparation
EP0002495B1 (de) * 1977-12-14 1984-02-15 Asta-Werke Aktiengesellschaft Chemische Fabrik Erzeugnisse zur Anwendung in der cytostatischen Therapie
DE2806866C3 (de) * 1978-02-17 1981-02-12 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld Verwendung von Salzen von Dithiodialkansulfonsäuren
DE3022599A1 (de) * 1979-06-18 1981-01-08 Glaxo Group Ltd Alkansaeurederivate
US4418206A (en) * 1982-03-22 1983-11-29 Syntex (U.S.A.) Inc. 9-Deoxy-9-methylene derivatives of (dl)-16-phenoxy and 16-phenoxy substituted prostatriene compounds
US4503072A (en) * 1982-12-22 1985-03-05 Merck & Co., Inc. Antihypercholesterolemic compounds

Also Published As

Publication number Publication date
EP0198542B1 (de) 1991-01-02
JPS61238722A (ja) 1986-10-24
JPH08277262A (ja) 1996-10-22
JP2553838B2 (ja) 1996-11-13
JP2611949B2 (ja) 1997-05-21
EP0198542A1 (de) 1986-10-22
US5019596A (en) 1991-05-28
DE3676335D1 (de) 1991-02-07
IT8520338A0 (it) 1985-04-15
IT1185551B (it) 1987-11-12

Similar Documents

Publication Publication Date Title
ES2032382T3 (es) Metodo para preparar un medicamento para la prevencion o tratamiento de la endometriosis.
ES2061975T3 (es) Derivados de triazol, su preparacion y su uso como fungicidas.
ATE145201T1 (de) Dihydro-isoquinolinderivate
NO903999D0 (no) Fremgangsmaate for fremstilling av gallesyrederivater og deres anvendelse som legemidler.
GR1001503B (el) Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών.
ATE59554T1 (de) Auf mercaptoethansulfonsaeuren basierende pharmazeutische zusammensetzungen, organische abkoemmlinge von mercaptoethansulfonsaeuren sowie verfahren zu deren herstellung.
ATE161836T1 (de) 4-substituierte-2-deoxy-2,3-didehydro alpha-d- neuraminsäure antivirale derivate
ATE63220T1 (de) Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben.
NO167380C (no) Dibasisk alkalimetallsalt av ravsyrederivat, konsentrat inneholdende samme for tilsetning til bensin og anvendelse av det dibasiske alkalimetallsalt i bensin.
ES2105362T3 (es) Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos.
FI940224A0 (fi) Oksikamia tai oksikamijohdannaisia sisältävät oftalmiset koostumukset
ATE249224T1 (de) Oxytetracyclin enthaltendes arzneimittel mit verzögerter wirksoffabgabe
DE69316382D1 (de) Herstellung von derivaten von n-acetyl neuraminicsäure
DK605589A (da) Anvendelse af aminobenzocycloalkaner eller syreadditionssalte deraf til fremstilling af et farmaceutikum, saaledes fremstillet praeparat og dettes anvendelse
DE59401990D1 (de) Imidazolyl-substituierte Phenylessigsäureprolinamide
WO1990003172A3 (en) Bile acids for treatment of viral infections
CA2038025A1 (en) Optically active alkylenedioxybenzene derivatives and their use in therapy
ATE86974T1 (de) (2-cyan-2-oximinoacetyl)-aminosaeure-derivate.
DE69121058T2 (de) Salze von Glykosaminoglykanen mit Aminosäureester, ihre Herstellung sowie sie enthaltende pharmazeutische Zusammensetzungen
DE3884508D1 (de) Cystein-derivate mit expectorans-wirkung.
ATE94168T1 (de) Peptide.
LV11524A (lv) Benzidamina izmantosana TNF izsaukto patologisko stavoklu arstesana
DE69517247D1 (de) Phosphorylierte Derivate von Verbindungen mit antiinflammatorischen oder analgetischer Wirkung
FR2470111B1 (fr) Derives de la decaprenylamine, leurs sels acides d'addition et composition pharmaceutique utilisant ces produits
CA2194576A1 (en) Long-acting oxytetracycline composition

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee