JPS5416491B2 - - Google Patents

Info

Publication number
JPS5416491B2
JPS5416491B2 JP12527273A JP12527273A JPS5416491B2 JP S5416491 B2 JPS5416491 B2 JP S5416491B2 JP 12527273 A JP12527273 A JP 12527273A JP 12527273 A JP12527273 A JP 12527273A JP S5416491 B2 JPS5416491 B2 JP S5416491B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP12527273A
Other languages
Japanese (ja)
Other versions
JPS4993342A (zh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4993342A publication Critical patent/JPS4993342A/ja
Publication of JPS5416491B2 publication Critical patent/JPS5416491B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP12527273A 1972-11-08 1973-11-07 Expired JPS5416491B2 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30481372A 1972-11-08 1972-11-08

Publications (2)

Publication Number Publication Date
JPS4993342A JPS4993342A (zh) 1974-09-05
JPS5416491B2 true JPS5416491B2 (zh) 1979-06-22

Family

ID=23178133

Family Applications (3)

Application Number Title Priority Date Filing Date
JP12527273A Expired JPS5416491B2 (zh) 1972-11-08 1973-11-07
JP51123737A Pending JPS5253841A (en) 1972-11-08 1976-10-15 Process for manufacture of intermediates of substituted omegaapentanolprostaglandins
JP51123738A Pending JPS5257147A (en) 1972-11-08 1976-10-15 Process for preparing omegaasubstituted pentanor prostagladines intermediates

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP51123737A Pending JPS5253841A (en) 1972-11-08 1976-10-15 Process for manufacture of intermediates of substituted omegaapentanolprostaglandins
JP51123738A Pending JPS5257147A (en) 1972-11-08 1976-10-15 Process for preparing omegaasubstituted pentanor prostagladines intermediates

Country Status (29)

Country Link
JP (3) JPS5416491B2 (zh)
AR (3) AR200585A1 (zh)
AT (3) AT367034B (zh)
AU (1) AU470375B2 (zh)
BE (1) BE806995A (zh)
CA (3) CA1085831A (zh)
CH (1) CH597176A5 (zh)
CS (3) CS182793B2 (zh)
DD (4) DD118856A5 (zh)
DE (1) DE2355540C2 (zh)
DK (1) DK144247C (zh)
ES (3) ES420325A1 (zh)
FI (1) FI60389C (zh)
FR (3) FR2205335B1 (zh)
GB (3) GB1456514A (zh)
HK (3) HK27979A (zh)
HU (3) HU171819B (zh)
IE (1) IE39537B1 (zh)
IL (1) IL43589A (zh)
IN (1) IN139384B (zh)
KE (3) KE2932A (zh)
MY (3) MY7900243A (zh)
NL (1) NL164273C (zh)
NO (3) NO147836C (zh)
PH (3) PH13272A (zh)
SE (4) SE448992B (zh)
SU (4) SU584766A3 (zh)
YU (3) YU39715B (zh)
ZA (1) ZA738554B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
GB1506816A (en) * 1975-03-31 1978-04-12 Upjohn Co Prostaglandins
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
GB1516414A (en) * 1975-08-22 1978-07-05 Ici Ltd Prostane derivatives
SE7809008L (sv) * 1977-12-12 1979-06-13 Upjohn Co Anvendning av amider av prostaglandintyp for att styra eller reglera reproduktionscykeln hos individer tillhorande deggdjursarter
DK523378A (da) * 1978-01-16 1979-07-17 Pfizer Fremgangsmaade til fremstilling af n-(tetrazol-5-yl) prostaglandin-carboxamider eller salte deraf
WO1999012898A1 (en) * 1997-09-09 1999-03-18 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
EP1159266B1 (en) 1999-03-05 2004-11-03 Duke University C-16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
JP2002329615A (ja) * 2001-05-02 2002-11-15 Ohira Denshi Kk トロイダルコイル
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
WO2006047466A2 (en) 2004-10-21 2006-05-04 Duke University Ophthamological drugs
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
IE37602B1 (en) * 1971-05-11 1977-08-31 Ici Ltd Cyclopentane derivatives

Also Published As

Publication number Publication date
PH13325A (en) 1980-03-13
JPS5257147A (en) 1977-05-11
NO148998B (no) 1983-10-17
YU270680A (en) 1983-04-27
KE2931A (en) 1979-03-30
NO750535L (zh) 1974-05-09
AR202931A1 (es) 1975-07-31
MY7900243A (en) 1979-12-31
ES420325A1 (es) 1976-04-16
HU173507B (hu) 1979-05-28
SU893130A3 (ru) 1981-12-23
DD109212A5 (zh) 1974-10-20
DE2365322B2 (de) 1977-02-24
KE2932A (en) 1979-03-30
AT353285B (de) 1979-11-12
CA1088931A (en) 1980-11-04
NO148998C (no) 1984-01-25
SE7700716L (sv) 1977-01-24
GB1456513A (en) 1976-11-24
YU288073A (en) 1982-02-28
ES433047A1 (es) 1976-11-01
FI60389B (fi) 1981-09-30
SE448992B (sv) 1987-03-30
DK144247C (da) 1982-07-12
DE2355540C2 (de) 1982-11-18
NO147836C (no) 1983-06-22
AT367034B (de) 1982-05-25
AR199966A1 (es) 1974-10-08
AT360672B (de) 1981-01-26
SU667141A3 (ru) 1979-06-05
FR2205335B1 (zh) 1978-07-13
AR200585A1 (es) 1974-11-22
DD119411A5 (zh) 1976-04-20
FR2283146B1 (zh) 1981-06-19
YU270780A (en) 1982-06-18
CS182791B2 (en) 1978-05-31
DK144247B (da) 1982-01-25
ATA544576A (de) 1980-06-15
ATA936973A (de) 1981-10-15
FR2279729B1 (zh) 1978-04-28
HK27979A (en) 1979-05-11
IN139384B (zh) 1976-06-12
HK28079A (en) 1979-05-11
GB1456512A (en) 1976-11-24
IE39537B1 (en) 1978-11-08
AU470375B2 (en) 1976-03-11
NO149139B (no) 1983-11-14
JPS4993342A (zh) 1974-09-05
DD118856A5 (zh) 1976-03-20
DD117233A5 (zh) 1976-01-05
PH13110A (en) 1979-11-28
SU745362A3 (ru) 1980-06-30
HK28179A (en) 1979-05-11
CS182793B2 (en) 1978-05-31
JPS5253841A (en) 1977-04-30
NO149139C (no) 1984-02-29
ATA544676A (de) 1979-04-15
SE7700718L (sv) 1977-01-24
SU584766A3 (ru) 1977-12-15
HU171819B (hu) 1978-03-28
FR2279729A1 (fr) 1976-02-20
YU37316B (en) 1984-08-31
ES433046A1 (es) 1977-06-16
DE2365322A1 (de) 1974-11-07
PH13272A (en) 1980-02-27
IE39537L (en) 1974-05-08
NL7315263A (zh) 1974-05-10
SE431756B (sv) 1984-02-27
FR2283146A1 (fr) 1976-03-26
SE436278B (sv) 1984-11-26
YU36975B (en) 1984-08-31
SE7700717L (sv) 1977-01-24
ZA738554B (en) 1974-09-25
CA1085831A (en) 1980-09-16
NO147836B (no) 1983-03-14
KE2930A (en) 1979-03-30
HU172703B (hu) 1978-11-28
CH597176A5 (zh) 1978-03-31
IL43589A0 (en) 1974-03-14
IL43589A (en) 1980-01-31
FR2205335A1 (zh) 1974-05-31
DE2355540A1 (de) 1974-05-22
AU6224773A (en) 1975-05-08
SE445111B (sv) 1986-06-02
MY7900246A (en) 1979-12-31
NO743493L (no) 1974-05-09
CS182794B2 (en) 1978-05-31
FI60389C (fi) 1982-01-11
NL164273C (nl) 1980-12-15
BE806995A (fr) 1974-05-07
GB1456514A (en) 1976-11-24
MY7900245A (en) 1979-12-31
CA1088930A (en) 1980-11-04
YU39715B (en) 1985-04-30

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