HK27979A - Substituted 16,17,18,19,20-pentanorprostaglandins - Google Patents

Substituted 16,17,18,19,20-pentanorprostaglandins

Info

Publication number
HK27979A
HK27979A HK279/79A HK27979A HK27979A HK 27979 A HK27979 A HK 27979A HK 279/79 A HK279/79 A HK 279/79A HK 27979 A HK27979 A HK 27979A HK 27979 A HK27979 A HK 27979A
Authority
HK
Hong Kong
Prior art keywords
pentanorprostaglandins
substituted
Prior art date
Application number
HK279/79A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HK27979A publication Critical patent/HK27979A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK279/79A 1972-11-08 1979-05-03 Substituted 16,17,18,19,20-pentanorprostaglandins HK27979A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30481372A 1972-11-08 1972-11-08

Publications (1)

Publication Number Publication Date
HK27979A true HK27979A (en) 1979-05-11

Family

ID=23178133

Family Applications (3)

Application Number Title Priority Date Filing Date
HK280/79A HK28079A (en) 1972-11-08 1979-05-03 Derivatives of cyclopentaneacetic acid
HK279/79A HK27979A (en) 1972-11-08 1979-05-03 Substituted 16,17,18,19,20-pentanorprostaglandins
HK281/79A HK28179A (en) 1972-11-08 1979-05-03 Substituted dialkyl 2-oxopropylphosphonates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK280/79A HK28079A (en) 1972-11-08 1979-05-03 Derivatives of cyclopentaneacetic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK281/79A HK28179A (en) 1972-11-08 1979-05-03 Substituted dialkyl 2-oxopropylphosphonates

Country Status (29)

Country Link
JP (3) JPS5416491B2 (zh)
AR (3) AR200585A1 (zh)
AT (3) AT367034B (zh)
AU (1) AU470375B2 (zh)
BE (1) BE806995A (zh)
CA (3) CA1085831A (zh)
CH (1) CH597176A5 (zh)
CS (3) CS182793B2 (zh)
DD (4) DD118856A5 (zh)
DE (1) DE2355540C2 (zh)
DK (1) DK144247C (zh)
ES (3) ES420325A1 (zh)
FI (1) FI60389C (zh)
FR (3) FR2205335B1 (zh)
GB (3) GB1456513A (zh)
HK (3) HK28079A (zh)
HU (3) HU172703B (zh)
IE (1) IE39537B1 (zh)
IL (1) IL43589A (zh)
IN (1) IN139384B (zh)
KE (3) KE2932A (zh)
MY (3) MY7900245A (zh)
NL (1) NL164273C (zh)
NO (3) NO147836C (zh)
PH (3) PH13272A (zh)
SE (4) SE448992B (zh)
SU (4) SU584766A3 (zh)
YU (3) YU39715B (zh)
ZA (1) ZA738554B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
GB1506817A (en) * 1975-03-31 1978-04-12 Upjohn Co Prostaglandins
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
GB1516414A (en) * 1975-08-22 1978-07-05 Ici Ltd Prostane derivatives
SE7809008L (sv) * 1977-12-12 1979-06-13 Upjohn Co Anvendning av amider av prostaglandintyp for att styra eller reglera reproduktionscykeln hos individer tillhorande deggdjursarter
DK523378A (da) * 1978-01-16 1979-07-17 Pfizer Fremgangsmaade til fremstilling af n-(tetrazol-5-yl) prostaglandin-carboxamider eller salte deraf
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
NZ513825A (en) 1999-03-05 2001-09-28 Procter & Gamble C 16 unsaturated FP-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
JP2002329615A (ja) * 2001-05-02 2002-11-15 Ohira Denshi Kk トロイダルコイル
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
US20060135609A1 (en) 2004-10-21 2006-06-22 Duke University Ophthamological drugs
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
IE37602B1 (en) * 1971-05-11 1977-08-31 Ici Ltd Cyclopentane derivatives

Also Published As

Publication number Publication date
HU172703B (hu) 1978-11-28
NO149139B (no) 1983-11-14
BE806995A (fr) 1974-05-07
HK28079A (en) 1979-05-11
ES420325A1 (es) 1976-04-16
HK28179A (en) 1979-05-11
AT367034B (de) 1982-05-25
GB1456514A (en) 1976-11-24
JPS5416491B2 (zh) 1979-06-22
MY7900246A (en) 1979-12-31
ES433046A1 (es) 1977-06-16
GB1456513A (en) 1976-11-24
FR2205335B1 (zh) 1978-07-13
GB1456512A (en) 1976-11-24
ES433047A1 (es) 1976-11-01
DK144247B (da) 1982-01-25
CS182793B2 (en) 1978-05-31
JPS5253841A (en) 1977-04-30
SE431756B (sv) 1984-02-27
DD109212A5 (zh) 1974-10-20
SU584766A3 (ru) 1977-12-15
FI60389C (fi) 1982-01-11
DE2365322A1 (de) 1974-11-07
CA1088931A (en) 1980-11-04
FR2283146A1 (fr) 1976-03-26
PH13272A (en) 1980-02-27
JPS5257147A (en) 1977-05-11
SE7700718L (sv) 1977-01-24
DK144247C (da) 1982-07-12
CS182791B2 (en) 1978-05-31
KE2932A (en) 1979-03-30
KE2930A (en) 1979-03-30
PH13325A (en) 1980-03-13
YU36975B (en) 1984-08-31
NO147836C (no) 1983-06-22
PH13110A (en) 1979-11-28
IE39537L (en) 1974-05-08
NL7315263A (zh) 1974-05-10
CA1085831A (en) 1980-09-16
CS182794B2 (en) 1978-05-31
NO743493L (no) 1974-05-09
ATA544676A (de) 1979-04-15
NO148998B (no) 1983-10-17
YU288073A (en) 1982-02-28
IE39537B1 (en) 1978-11-08
YU270680A (en) 1983-04-27
ZA738554B (en) 1974-09-25
AT360672B (de) 1981-01-26
AR200585A1 (es) 1974-11-22
ATA544576A (de) 1980-06-15
NL164273C (nl) 1980-12-15
AU6224773A (en) 1975-05-08
ATA936973A (de) 1981-10-15
DE2355540C2 (de) 1982-11-18
SE7700717L (sv) 1977-01-24
FR2283146B1 (zh) 1981-06-19
IL43589A (en) 1980-01-31
AU470375B2 (en) 1976-03-11
NO750535L (zh) 1974-05-09
KE2931A (en) 1979-03-30
MY7900243A (en) 1979-12-31
IL43589A0 (en) 1974-03-14
SU893130A3 (ru) 1981-12-23
MY7900245A (en) 1979-12-31
IN139384B (zh) 1976-06-12
DD119411A5 (zh) 1976-04-20
SU745362A3 (ru) 1980-06-30
HU171819B (hu) 1978-03-28
DE2355540A1 (de) 1974-05-22
DE2365322B2 (de) 1977-02-24
JPS4993342A (zh) 1974-09-05
SE445111B (sv) 1986-06-02
NO148998C (no) 1984-01-25
FR2205335A1 (zh) 1974-05-31
FR2279729A1 (fr) 1976-02-20
SE7700716L (sv) 1977-01-24
AT353285B (de) 1979-11-12
AR202931A1 (es) 1975-07-31
YU270780A (en) 1982-06-18
DD117233A5 (zh) 1976-01-05
FI60389B (fi) 1981-09-30
CA1088930A (en) 1980-11-04
SU667141A3 (ru) 1979-06-05
AR199966A1 (es) 1974-10-08
HU173507B (hu) 1979-05-28
SE436278B (sv) 1984-11-26
NO149139C (no) 1984-02-29
YU37316B (en) 1984-08-31
FR2279729B1 (zh) 1978-04-28
NO147836B (no) 1983-03-14
YU39715B (en) 1985-04-30
SE448992B (sv) 1987-03-30
CH597176A5 (zh) 1978-03-31
DD118856A5 (zh) 1976-03-20

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