SE431756B - Fenoxi-2-oxopropylfosfonat till anvendning som mellanprodukt vid framstellning av nya w-pentanorprostaglandiner - Google Patents

Fenoxi-2-oxopropylfosfonat till anvendning som mellanprodukt vid framstellning av nya w-pentanorprostaglandiner

Info

Publication number
SE431756B
SE431756B SE7700718A SE7700718A SE431756B SE 431756 B SE431756 B SE 431756B SE 7700718 A SE7700718 A SE 7700718A SE 7700718 A SE7700718 A SE 7700718A SE 431756 B SE431756 B SE 431756B
Authority
SE
Sweden
Prior art keywords
pentanorprostaglandines
phenoxi
oxopropylphosphonate
preparation
new
Prior art date
Application number
SE7700718A
Other languages
English (en)
Swedish (sv)
Other versions
SE7700718L (sv
Inventor
J S Bindra
M R Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7700718L publication Critical patent/SE7700718L/xx
Publication of SE431756B publication Critical patent/SE431756B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
SE7700718A 1972-11-08 1977-01-24 Fenoxi-2-oxopropylfosfonat till anvendning som mellanprodukt vid framstellning av nya w-pentanorprostaglandiner SE431756B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30481372A 1972-11-08 1972-11-08

Publications (2)

Publication Number Publication Date
SE7700718L SE7700718L (sv) 1977-01-24
SE431756B true SE431756B (sv) 1984-02-27

Family

ID=23178133

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7314686A SE448992B (sv) 1972-11-08 1973-10-29 Forfarande for framstellning av en omega-pentanorprostaglandin ur e- eller f-serierna
SE7700717A SE436278B (sv) 1972-11-08 1977-01-24 Cyklopentanderivat for anvendning sasom intermediat vid framstellning av prostaglandinforeningar
SE7700716A SE445111B (sv) 1972-11-08 1977-01-24 Substituerad omega-pentanorprostaglandin ur e- eller f-serien for anvendning som antifertilitetsmedel
SE7700718A SE431756B (sv) 1972-11-08 1977-01-24 Fenoxi-2-oxopropylfosfonat till anvendning som mellanprodukt vid framstellning av nya w-pentanorprostaglandiner

Family Applications Before (3)

Application Number Title Priority Date Filing Date
SE7314686A SE448992B (sv) 1972-11-08 1973-10-29 Forfarande for framstellning av en omega-pentanorprostaglandin ur e- eller f-serierna
SE7700717A SE436278B (sv) 1972-11-08 1977-01-24 Cyklopentanderivat for anvendning sasom intermediat vid framstellning av prostaglandinforeningar
SE7700716A SE445111B (sv) 1972-11-08 1977-01-24 Substituerad omega-pentanorprostaglandin ur e- eller f-serien for anvendning som antifertilitetsmedel

Country Status (29)

Country Link
JP (3) JPS5416491B2 (xx)
AR (3) AR200585A1 (xx)
AT (3) AT367034B (xx)
AU (1) AU470375B2 (xx)
BE (1) BE806995A (xx)
CA (3) CA1085831A (xx)
CH (1) CH597176A5 (xx)
CS (3) CS182794B2 (xx)
DD (4) DD118856A5 (xx)
DE (1) DE2355540C2 (xx)
DK (1) DK144247C (xx)
ES (3) ES420325A1 (xx)
FI (1) FI60389C (xx)
FR (3) FR2205335B1 (xx)
GB (3) GB1456514A (xx)
HK (3) HK27979A (xx)
HU (3) HU171819B (xx)
IE (1) IE39537B1 (xx)
IL (1) IL43589A (xx)
IN (1) IN139384B (xx)
KE (3) KE2930A (xx)
MY (3) MY7900245A (xx)
NL (1) NL164273C (xx)
NO (3) NO147836C (xx)
PH (3) PH13272A (xx)
SE (4) SE448992B (xx)
SU (4) SU584766A3 (xx)
YU (3) YU39715B (xx)
ZA (1) ZA738554B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
GB1506817A (en) * 1975-03-31 1978-04-12 Upjohn Co Prostaglandins
US3986764A (en) * 1975-03-31 1976-10-19 Gte Automatic Electric Laboratories Incorporated Panel for supporting a pair of elongated mating connectors and selectively locking them together
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
GB1516414A (en) * 1975-08-22 1978-07-05 Ici Ltd Prostane derivatives
SE7809008L (sv) * 1977-12-12 1979-06-13 Upjohn Co Anvendning av amider av prostaglandintyp for att styra eller reglera reproduktionscykeln hos individer tillhorande deggdjursarter
IN150279B (xx) * 1978-01-16 1982-09-04 Pfizer
CA2303801C (en) * 1997-09-09 2005-05-10 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
PL350917A1 (en) 1999-03-05 2003-02-10 Procter & Gamble C16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
JP2002329615A (ja) * 2001-05-02 2002-11-15 Ohira Denshi Kk トロイダルコイル
US6476064B1 (en) * 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
US20060135609A1 (en) 2004-10-21 2006-06-22 Duke University Ophthamological drugs
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1324737A (en) * 1970-11-02 1973-07-25 Upjohn Co Prostaglandins and the preparation thereof
IE37602B1 (en) * 1971-05-11 1977-08-31 Ici Ltd Cyclopentane derivatives

Also Published As

Publication number Publication date
AT367034B (de) 1982-05-25
SU893130A3 (ru) 1981-12-23
SE448992B (sv) 1987-03-30
NO750535L (xx) 1974-05-09
NO743493L (no) 1974-05-09
MY7900246A (en) 1979-12-31
NO148998C (no) 1984-01-25
SU667141A3 (ru) 1979-06-05
FI60389C (fi) 1982-01-11
SE7700717L (sv) 1977-01-24
DD109212A5 (xx) 1974-10-20
MY7900245A (en) 1979-12-31
JPS5257147A (en) 1977-05-11
DE2355540C2 (de) 1982-11-18
AR199966A1 (es) 1974-10-08
FI60389B (fi) 1981-09-30
DD117233A5 (xx) 1976-01-05
JPS5416491B2 (xx) 1979-06-22
NO147836B (no) 1983-03-14
NO147836C (no) 1983-06-22
SE7700718L (sv) 1977-01-24
YU37316B (en) 1984-08-31
DK144247B (da) 1982-01-25
AT360672B (de) 1981-01-26
SE436278B (sv) 1984-11-26
ATA544576A (de) 1980-06-15
AU470375B2 (en) 1976-03-11
PH13325A (en) 1980-03-13
BE806995A (fr) 1974-05-07
ATA936973A (de) 1981-10-15
KE2931A (en) 1979-03-30
FR2283146B1 (xx) 1981-06-19
IE39537L (en) 1974-05-08
FR2283146A1 (fr) 1976-03-26
JPS5253841A (en) 1977-04-30
DE2355540A1 (de) 1974-05-22
NO149139C (no) 1984-02-29
IE39537B1 (en) 1978-11-08
ES420325A1 (es) 1976-04-16
YU36975B (en) 1984-08-31
CS182791B2 (en) 1978-05-31
ES433046A1 (es) 1977-06-16
GB1456513A (en) 1976-11-24
SU745362A3 (ru) 1980-06-30
AR200585A1 (es) 1974-11-22
AT353285B (de) 1979-11-12
CA1088931A (en) 1980-11-04
GB1456514A (en) 1976-11-24
NO148998B (no) 1983-10-17
YU270680A (en) 1983-04-27
SE445111B (sv) 1986-06-02
GB1456512A (en) 1976-11-24
IN139384B (xx) 1976-06-12
PH13272A (en) 1980-02-27
PH13110A (en) 1979-11-28
NO149139B (no) 1983-11-14
JPS4993342A (xx) 1974-09-05
FR2205335A1 (xx) 1974-05-31
NL164273C (nl) 1980-12-15
SE7700716L (sv) 1977-01-24
HK27979A (en) 1979-05-11
CH597176A5 (xx) 1978-03-31
AU6224773A (en) 1975-05-08
CS182794B2 (en) 1978-05-31
KE2930A (en) 1979-03-30
DK144247C (da) 1982-07-12
CS182793B2 (en) 1978-05-31
KE2932A (en) 1979-03-30
MY7900243A (en) 1979-12-31
YU39715B (en) 1985-04-30
HU173507B (hu) 1979-05-28
IL43589A0 (en) 1974-03-14
HU171819B (hu) 1978-03-28
HK28079A (en) 1979-05-11
ES433047A1 (es) 1976-11-01
IL43589A (en) 1980-01-31
DE2365322A1 (de) 1974-11-07
HK28179A (en) 1979-05-11
YU270780A (en) 1982-06-18
CA1085831A (en) 1980-09-16
HU172703B (hu) 1978-11-28
FR2279729A1 (fr) 1976-02-20
DD118856A5 (xx) 1976-03-20
NL7315263A (xx) 1974-05-10
DE2365322B2 (de) 1977-02-24
FR2205335B1 (xx) 1978-07-13
DD119411A5 (xx) 1976-04-20
ATA544676A (de) 1979-04-15
FR2279729B1 (xx) 1978-04-28
YU288073A (en) 1982-02-28
CA1088930A (en) 1980-11-04
AR202931A1 (es) 1975-07-31
SU584766A3 (ru) 1977-12-15
ZA738554B (en) 1974-09-25

Similar Documents

Publication Publication Date Title
SE412062B (sv) Nya cyklohexan-1-3-dion-derivat for anvendning som herbicid
SE390967B (sv) Tiokarbamider till anvendning som mellanprodukter vid framstellning av isotiokarbamider med farmaceautisk verkan
FI56676B (fi) Foerfarande foer framstaellning av nya amidderivat av nonapeptid som befraemjar loesgoerandet av aeggceller
SE431756B (sv) Fenoxi-2-oxopropylfosfonat till anvendning som mellanprodukt vid framstellning av nya w-pentanorprostaglandiner
SE435289B (sv) O-substituerade 7 beta-amino-3-cefem-3-ol-4-karbonsyraderivat till anvendning som mellanprodukt for framstellning av o-substituerade 7 beta-acylamino-3-cefem-3-ol-4-karbonsyraderivat
SE384504B (sv) 6-substituerade-4-halogen-1,2-dihydro-1-hydroxi-2-iminopyrimidiner till anvendning vid framstellning av motsvarande 4-aminoforeningar
SE400555B (sv) N-substituerade beta-amino-alfa-bensylakrylnitrilforening till anvendning som mellanprodukt vid framstellning av 5-bensyl-pyrimidiner
SE387358B (sv) Vid rumstemperatur till elaster vulkbara massor samt butoxiacetoxikiselforeningar for framstellning av massorna
SE403106B (sv) Forfarande vid framstellning av 14-hydroximorfinanderivat
FI55802C (fi) Anordning vid skeppsskrov
SE396592B (sv) Foreningen difluorometyl-2,2,3,3-tetrafluoropropyleter till anvendning som mellanprodukt vid framstellning av difluormetyl-1,2,2,3,3-pentafluoropropyleter
FI54192B (fi) Anordning vid s k cyklonugn
FI54359B (fi) Kalander foer anvaendning vid glaettning av en pappersbana
FI54411B (fi) Anordning vid vaermevaexlare
SE423098B (sv) Forening till anvendning vid framstellning av cefalosporansyraforeningar
SE386902B (sv) Forfarande for framstellning av nya cefalosporiner
SE7700287L (sv) Nya foreningar till anvendning som mellanprodukter vid framstellning av aminosubstituerade tetracykliska foreningar
SE416543B (sv) Sibstituerat cyklopentanderivat till anvendning som mellanprodukt vid framstellning av farmaceutiskt aktiva prostaglandinanaloger
SE7611466L (sv) Mellanforening till anvendning vid framstellning av en ny d-2-substituerad-6-metyl-8-substituerad ergolin
SE7604140L (sv) Nya triisocyanater till anvendning vid framstellning av polyuratanplaster
FI54023C (fi) Anordning vid eldstaeder uppbyggda av s k membranvaeggar
FI53825B (fi) Framstaellning av etylenpropylenkopolymer med trifenylfosfit som katalysatorhjaelpmedel
SE418744B (sv) Foreningar till anvendning som mellanprodukter vid framstellning av prostaglandiner
SE384511B (sv) 7-skyddad amino-delta?722?71-cefalosporansyraester, for anvendning som mellanforening vid framstellning av delta?723?71-cefalosporinantibiotika
SE421000B (sv) Forening till anvendning som mellanprodukt vid framstellning av triazolbensodiazepinderivat

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7700718-5

Effective date: 19930510

Format of ref document f/p: F