JPH11509214A - 動脈壁のアテローム硬化性分解の予防および治療における1,4−ジヒドロピリジン誘導体の使用 - Google Patents

動脈壁のアテローム硬化性分解の予防および治療における1,4−ジヒドロピリジン誘導体の使用

Info

Publication number
JPH11509214A
JPH11509214A JP9506222A JP50622297A JPH11509214A JP H11509214 A JPH11509214 A JP H11509214A JP 9506222 A JP9506222 A JP 9506222A JP 50622297 A JP50622297 A JP 50622297A JP H11509214 A JPH11509214 A JP H11509214A
Authority
JP
Japan
Prior art keywords
lercanidipine
medicament
preparation
compound
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9506222A
Other languages
English (en)
Japanese (ja)
Inventor
アブラハム サータニ
アメデオ レオナルディ
ロドルフォ テスタ
Original Assignee
レコルダチ エッセ.ア.,ケミカル アンド ファーマシューティカル カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by レコルダチ エッセ.ア.,ケミカル アンド ファーマシューティカル カンパニー filed Critical レコルダチ エッセ.ア.,ケミカル アンド ファーマシューティカル カンパニー
Publication of JPH11509214A publication Critical patent/JPH11509214A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP9506222A 1995-07-14 1996-06-28 動脈壁のアテローム硬化性分解の予防および治療における1,4−ジヒドロピリジン誘導体の使用 Pending JPH11509214A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI951513A IT1275532B (it) 1995-07-14 1995-07-14 Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa
IT95A001513 1995-07-14
PCT/EP1996/002872 WO1997003669A1 (en) 1995-07-14 1996-06-28 Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls

Publications (1)

Publication Number Publication Date
JPH11509214A true JPH11509214A (ja) 1999-08-17

Family

ID=11371972

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9506222A Pending JPH11509214A (ja) 1995-07-14 1996-06-28 動脈壁のアテローム硬化性分解の予防および治療における1,4−ジヒドロピリジン誘導体の使用

Country Status (19)

Country Link
EP (1) EP0839036B1 (xx)
JP (1) JPH11509214A (xx)
KR (1) KR19990028741A (xx)
CN (1) CN1190345A (xx)
AT (1) ATE183644T1 (xx)
AU (1) AU690471B2 (xx)
CA (1) CA2219501A1 (xx)
CZ (1) CZ11698A3 (xx)
DE (1) DE69603968T2 (xx)
DK (1) DK0839036T3 (xx)
ES (1) ES2138359T3 (xx)
GR (1) GR3031096T3 (xx)
HU (1) HUP9802736A3 (xx)
IL (1) IL122302A (xx)
IT (1) IT1275532B (xx)
NO (1) NO980171L (xx)
SK (1) SK4198A3 (xx)
WO (1) WO1997003669A1 (xx)
ZA (1) ZA965924B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504045A (ja) * 2001-08-06 2005-02-10 レコーダチ アイルランド リミテッド 塩酸レルカニジピンの新規な原形および結晶性形状

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852737B2 (en) 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
EP2585051B2 (en) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
PT2627173E (pt) 2010-10-12 2015-07-24 Medicines Co Formulações de clevidipina em emulsão contendo agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2654729B1 (en) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504045A (ja) * 2001-08-06 2005-02-10 レコーダチ アイルランド リミテッド 塩酸レルカニジピンの新規な原形および結晶性形状

Also Published As

Publication number Publication date
IL122302A0 (en) 1998-04-05
AU690471B2 (en) 1998-04-23
DE69603968D1 (de) 1999-09-30
ATE183644T1 (de) 1999-09-15
DK0839036T3 (da) 2000-01-24
ITMI951513A1 (it) 1997-01-14
HUP9802736A3 (en) 2000-03-28
SK4198A3 (en) 1998-05-06
KR19990028741A (ko) 1999-04-15
IT1275532B (it) 1997-08-07
IL122302A (en) 2000-08-13
EP0839036B1 (en) 1999-08-25
CZ11698A3 (cs) 1998-06-17
ZA965924B (en) 1997-01-30
WO1997003669A1 (en) 1997-02-06
GR3031096T3 (en) 1999-12-31
AU6516496A (en) 1997-02-18
ITMI951513A0 (it) 1995-07-14
DE69603968T2 (de) 2000-04-06
NO980171D0 (no) 1998-01-14
NO980171L (no) 1998-01-14
CN1190345A (zh) 1998-08-12
ES2138359T3 (es) 2000-01-01
CA2219501A1 (en) 1997-02-06
HUP9802736A2 (hu) 1999-03-29
EP0839036A1 (en) 1998-05-06

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