ATE183644T1 - Verwendung von 1,4-dihydropyridinderivaten in der prävention und therapie der atherosklerotischen degeneration von arterienwänden - Google Patents

Verwendung von 1,4-dihydropyridinderivaten in der prävention und therapie der atherosklerotischen degeneration von arterienwänden

Info

Publication number
ATE183644T1
ATE183644T1 AT96924834T AT96924834T ATE183644T1 AT E183644 T1 ATE183644 T1 AT E183644T1 AT 96924834 T AT96924834 T AT 96924834T AT 96924834 T AT96924834 T AT 96924834T AT E183644 T1 ATE183644 T1 AT E183644T1
Authority
AT
Austria
Prior art keywords
therapy
prevention
lercanidipine
atherosclerotic
dihydropyridine derivatives
Prior art date
Application number
AT96924834T
Other languages
English (en)
Inventor
Abraham Sartani
Amedeo Leonardi
Rodolfo Testa
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of ATE183644T1 publication Critical patent/ATE183644T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96924834T 1995-07-14 1996-06-28 Verwendung von 1,4-dihydropyridinderivaten in der prävention und therapie der atherosklerotischen degeneration von arterienwänden ATE183644T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI951513A IT1275532B (it) 1995-07-14 1995-07-14 Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa

Publications (1)

Publication Number Publication Date
ATE183644T1 true ATE183644T1 (de) 1999-09-15

Family

ID=11371972

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96924834T ATE183644T1 (de) 1995-07-14 1996-06-28 Verwendung von 1,4-dihydropyridinderivaten in der prävention und therapie der atherosklerotischen degeneration von arterienwänden

Country Status (19)

Country Link
EP (1) EP0839036B1 (de)
JP (1) JPH11509214A (de)
KR (1) KR19990028741A (de)
CN (1) CN1190345A (de)
AT (1) ATE183644T1 (de)
AU (1) AU690471B2 (de)
CA (1) CA2219501A1 (de)
CZ (1) CZ11698A3 (de)
DE (1) DE69603968T2 (de)
DK (1) DK0839036T3 (de)
ES (1) ES2138359T3 (de)
GR (1) GR3031096T3 (de)
HU (1) HUP9802736A3 (de)
IL (1) IL122302A (de)
IT (1) IT1275532B (de)
NO (1) NO980171L (de)
SK (1) SK4198A3 (de)
WO (1) WO1997003669A1 (de)
ZA (1) ZA965924B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852737B2 (en) 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011726A1 (it) * 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Forme polimorfe della lercanidipina cloridrato
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
EP2585051B2 (de) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
WO2012051116A1 (en) 2010-10-12 2012-04-19 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
WO2012085249A2 (en) 2010-12-24 2012-06-28 Krka, D.D., Novo Mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters

Also Published As

Publication number Publication date
ITMI951513A0 (it) 1995-07-14
EP0839036B1 (de) 1999-08-25
HUP9802736A3 (en) 2000-03-28
AU6516496A (en) 1997-02-18
IL122302A0 (en) 1998-04-05
IT1275532B (it) 1997-08-07
SK4198A3 (en) 1998-05-06
NO980171D0 (no) 1998-01-14
DK0839036T3 (da) 2000-01-24
GR3031096T3 (en) 1999-12-31
HUP9802736A2 (hu) 1999-03-29
JPH11509214A (ja) 1999-08-17
KR19990028741A (ko) 1999-04-15
ES2138359T3 (es) 2000-01-01
ITMI951513A1 (it) 1997-01-14
NO980171L (no) 1998-01-14
CA2219501A1 (en) 1997-02-06
WO1997003669A1 (en) 1997-02-06
EP0839036A1 (de) 1998-05-06
AU690471B2 (en) 1998-04-23
CZ11698A3 (cs) 1998-06-17
DE69603968T2 (de) 2000-04-06
CN1190345A (zh) 1998-08-12
ZA965924B (en) 1997-01-30
DE69603968D1 (de) 1999-09-30
IL122302A (en) 2000-08-13

Similar Documents

Publication Publication Date Title
BG101647A (en) Low molecular weight bicyclic thrombin inhibitors
AR017639A1 (es) Procedimiento de la alquilacion directa en una etapa, en las posiciones 7 y 10 simultaneamente de las dos funciones hidroxilos de la 10-desacetilbacatina o de los derivados de esta ultima esterificados en la posicion 13.
ATE188469T1 (de) Alkoxy-4(1h)-pyridon-derivative, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2077A1 (fr) Derives benzoiques et phenylacetiques,procedes pour leur preparation et compositions pharmaceutiques en contenant
FI942076A (fi) Sappihappojohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkaaineina
IS4536A (is) Ný taxóíð, aðferð til framleiðslu þeirra og lyfjasamsetningar sem innihalda þau
AU7053494A (en) Method of treating coronary vascular disease using docosahexaenoic acid
IE893123L (en) Use of gamma-interferon for the treatment of vascular¹stenosis
DE69526120T2 (de) Verwendung von nebivolol als anti-atherogenisches mittel
ATE183644T1 (de) Verwendung von 1,4-dihydropyridinderivaten in der prävention und therapie der atherosklerotischen degeneration von arterienwänden
AU6914296A (en) Left coronary artery catheter
DK0441279T3 (da) Bilobalid-phospholipid-komplekser, deres anvendelse og sammensætninger, der indeholder dem
DE69429806D1 (de) Pharmazeutische zusammensetzungen zur prävention und behandlung von krebserkrankungen und verfahren für ihre herstellung
ATE140455T1 (de) Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
TW372962B (en) Pharmaceutical compositions for the prevention, arrest or reversal of atherosclerotic degradation in the arterial walls of a patient
NO974267D0 (no) Aminotetralinderivat for behandling av kardiovaskulære sykdommer
DE69011046D1 (de) Pyridinderivate, Verfahren zur Herstellung und pharmazeutische Zusammensetzungen.
DE59200566D1 (de) Aryl-Chinolyl-substituierte 1,4-Dihydropyridin-dicarbonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln.
NO953322L (no) Anvendelse av 1,4-dihydropyridin-3,5-dikarboksylsyreestere som legemidler
DE69626148D1 (de) Pyrazolidinderivate, Radikalfänger sowie Hirninfarkt und Hirnoedem unterdrückende Mittel
ITMI932468A0 (it) Nuovi difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
DE69313534T2 (de) Digitoxigenin und Dihydrodigitoxigenin 3-beta-Derivate und pharmazeutische Präparate davon, zur Behandlung von hypertonie
AU7389496A (en) Methods and compositions for treating vascular stenosis
ITMI913511A0 (it) Derivati dell'eserolina ad attivita' anticolinesterasica,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
MX9803315A (es) Queto acidos aromaticos y sus derivados como inhibidores de metaloproteinasas matriz.

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee