ZA965924B - Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls - Google Patents

Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls

Info

Publication number
ZA965924B
ZA965924B ZA965924A ZA965924A ZA965924B ZA 965924 B ZA965924 B ZA 965924B ZA 965924 A ZA965924 A ZA 965924A ZA 965924 A ZA965924 A ZA 965924A ZA 965924 B ZA965924 B ZA 965924B
Authority
ZA
South Africa
Prior art keywords
arterial walls
therapy
prevention
lercanidipine
atherosclerotic
Prior art date
Application number
ZA965924A
Other languages
English (en)
Inventor
Abraham Sartani
Amedeo Leonardi
Rodolfo Testa
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of ZA965924B publication Critical patent/ZA965924B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA965924A 1995-07-14 1996-07-12 Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls ZA965924B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI951513A IT1275532B (it) 1995-07-14 1995-07-14 Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa

Publications (1)

Publication Number Publication Date
ZA965924B true ZA965924B (en) 1997-01-30

Family

ID=11371972

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA965924A ZA965924B (en) 1995-07-14 1996-07-12 Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls

Country Status (19)

Country Link
EP (1) EP0839036B1 (de)
JP (1) JPH11509214A (de)
KR (1) KR19990028741A (de)
CN (1) CN1190345A (de)
AT (1) ATE183644T1 (de)
AU (1) AU690471B2 (de)
CA (1) CA2219501A1 (de)
CZ (1) CZ11698A3 (de)
DE (1) DE69603968T2 (de)
DK (1) DK0839036T3 (de)
ES (1) ES2138359T3 (de)
GR (1) GR3031096T3 (de)
HU (1) HUP9802736A3 (de)
IL (1) IL122302A (de)
IT (1) IT1275532B (de)
NO (1) NO980171L (de)
SK (1) SK4198A3 (de)
WO (1) WO1997003669A1 (de)
ZA (1) ZA965924B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852737B2 (en) 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011726A1 (it) * 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Forme polimorfe della lercanidipina cloridrato
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
EP2585051B2 (de) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen
PT2627173E (pt) 2010-10-12 2015-07-24 Medicines Co Formulações de clevidipina em emulsão contendo agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2654729B1 (de) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Orale homogene pharmazeutische zubereitung enthaltend lercanidipine und enalapril oder ihre pharmazeutische salze zusammen mit einer organischen säure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters

Also Published As

Publication number Publication date
IL122302A0 (en) 1998-04-05
AU690471B2 (en) 1998-04-23
DE69603968D1 (de) 1999-09-30
ATE183644T1 (de) 1999-09-15
DK0839036T3 (da) 2000-01-24
ITMI951513A1 (it) 1997-01-14
HUP9802736A3 (en) 2000-03-28
SK4198A3 (en) 1998-05-06
KR19990028741A (ko) 1999-04-15
IT1275532B (it) 1997-08-07
IL122302A (en) 2000-08-13
EP0839036B1 (de) 1999-08-25
CZ11698A3 (cs) 1998-06-17
WO1997003669A1 (en) 1997-02-06
GR3031096T3 (en) 1999-12-31
AU6516496A (en) 1997-02-18
ITMI951513A0 (it) 1995-07-14
JPH11509214A (ja) 1999-08-17
DE69603968T2 (de) 2000-04-06
NO980171D0 (no) 1998-01-14
NO980171L (no) 1998-01-14
CN1190345A (zh) 1998-08-12
ES2138359T3 (es) 2000-01-01
CA2219501A1 (en) 1997-02-06
HUP9802736A2 (hu) 1999-03-29
EP0839036A1 (de) 1998-05-06

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