IL122302A - Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives - Google Patents

Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives

Info

Publication number
IL122302A
IL122302A IL12230296A IL12230296A IL122302A IL 122302 A IL122302 A IL 122302A IL 12230296 A IL12230296 A IL 12230296A IL 12230296 A IL12230296 A IL 12230296A IL 122302 A IL122302 A IL 122302A
Authority
IL
Israel
Prior art keywords
derivatives
medicament
therapy
prevention
preparation
Prior art date
Application number
IL12230296A
Other languages
English (en)
Other versions
IL122302A0 (en
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of IL122302A0 publication Critical patent/IL122302A0/xx
Publication of IL122302A publication Critical patent/IL122302A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL12230296A 1995-07-14 1996-06-28 Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives IL122302A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI951513A IT1275532B (it) 1995-07-14 1995-07-14 Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa
PCT/EP1996/002872 WO1997003669A1 (en) 1995-07-14 1996-06-28 Use of 1,4-dihydropyridine derivatives in the prevention and therapy of atherosclerotic degradation of arterial walls

Publications (2)

Publication Number Publication Date
IL122302A0 IL122302A0 (en) 1998-04-05
IL122302A true IL122302A (en) 2000-08-13

Family

ID=11371972

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12230296A IL122302A (en) 1995-07-14 1996-06-28 Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives

Country Status (19)

Country Link
EP (1) EP0839036B1 (xx)
JP (1) JPH11509214A (xx)
KR (1) KR19990028741A (xx)
CN (1) CN1190345A (xx)
AT (1) ATE183644T1 (xx)
AU (1) AU690471B2 (xx)
CA (1) CA2219501A1 (xx)
CZ (1) CZ11698A3 (xx)
DE (1) DE69603968T2 (xx)
DK (1) DK0839036T3 (xx)
ES (1) ES2138359T3 (xx)
GR (1) GR3031096T3 (xx)
HU (1) HUP9802736A3 (xx)
IL (1) IL122302A (xx)
IT (1) IT1275532B (xx)
NO (1) NO980171L (xx)
SK (1) SK4198A3 (xx)
WO (1) WO1997003669A1 (xx)
ZA (1) ZA965924B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852737B2 (en) 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011726A1 (it) * 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Forme polimorfe della lercanidipina cloridrato
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
EP2585051B2 (en) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
PT2627173E (pt) 2010-10-12 2015-07-24 Medicines Co Formulações de clevidipina em emulsão contendo agentes antimicrobianos
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2654729B1 (en) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters

Also Published As

Publication number Publication date
IL122302A0 (en) 1998-04-05
AU690471B2 (en) 1998-04-23
DE69603968D1 (de) 1999-09-30
ATE183644T1 (de) 1999-09-15
DK0839036T3 (da) 2000-01-24
ITMI951513A1 (it) 1997-01-14
HUP9802736A3 (en) 2000-03-28
SK4198A3 (en) 1998-05-06
KR19990028741A (ko) 1999-04-15
IT1275532B (it) 1997-08-07
EP0839036B1 (en) 1999-08-25
CZ11698A3 (cs) 1998-06-17
ZA965924B (en) 1997-01-30
WO1997003669A1 (en) 1997-02-06
GR3031096T3 (en) 1999-12-31
AU6516496A (en) 1997-02-18
ITMI951513A0 (it) 1995-07-14
JPH11509214A (ja) 1999-08-17
DE69603968T2 (de) 2000-04-06
NO980171D0 (no) 1998-01-14
NO980171L (no) 1998-01-14
CN1190345A (zh) 1998-08-12
ES2138359T3 (es) 2000-01-01
CA2219501A1 (en) 1997-02-06
HUP9802736A2 (hu) 1999-03-29
EP0839036A1 (en) 1998-05-06

Similar Documents

Publication Publication Date Title
HUP9603530A3 (en) Process for producing pharmaceutical compositions containing agent in polymer-matrix and in solid solution form and these medicaments
IL117728A0 (en) Pharmaceutical compositions for transdermal administration
IL117265A0 (en) Benzazepine- benzoxazepine- and benzothiazepine-n-acetic acid derivatives their preparation and pharmaceutical compositions containing them
HUT52089A (en) Process for producing triazole derivatives and pharmaceutical compositions comprising such compounds as active ingredient
IL117193A0 (en) Poly-pyrrolecarbox-amidenaphthalenic acid derivatives their preparation and pharmaceutical compositions containing them
HU208256B (en) Process for producing pharmaceutical compositions suitable for the selective reduction of lipoid level of blood
AU5157590A (en) Pharmaceutical compositions for oral administration
IL118483A (en) Compounds for use in the preparation of medicaments for inhibiting vascular smooth muscle cell migration and pharmaceutical formulations containing them
IL122302A (en) Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives
HUP9700005A3 (en) 2-ureido-benzamide derivatives and pharmaceutical compositions containing them as active agent
CA2100126A1 (en) 5,10-Methylenetetrahydrofolic Acid-Cyclodextrin Inclusion Compounds
IL112936A0 (en) Quinolone - and - naphthyridone - carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
IL97501A0 (en) 4-pyridone derivatives,their preparation and pharmaceutical compositions containing them
HUP9802897A3 (en) Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, the use thereof in the treatment of vascular diseases and pharmaceutical composition containing the compound as active ingredient
HUT58082A (en) Process for producing chroman derivatives and pharmaceutical compositions comprising such compounds as active ingredient
UA35566C2 (uk) Лікарський засіб для профілактики і лікування порушень ліпоїдного і холестеринового обміну речовин і спосіб профілактики і лікування цих порушень
IL102032A0 (en) 2-amino-5-cyano-1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them
TW372962B (en) Pharmaceutical compositions for the prevention, arrest or reversal of atherosclerotic degradation in the arterial walls of a patient
HUP9901247A3 (en) Use of naphthimidazole-, naphthoxazole- and naphthothiazole-diones for the preparation of pharmaceutical compositions treating diseases caused by vascular function deficiency
AU660296B2 (en) Pharmaceutical compositions containing functionalized vinylazoles, use of these vinylazoles for producing medicaments, these vinylazoles themselves and process for producing the same
IT1237509B (it) Complessi con le ciclodestrine indicati per il trattamento di tutte leforme anemiche da carenza di folati, loro preparazione e relative composizioni farmaceutiche
IL108930A0 (en) 2,3-Diamino-3- hydroxycarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
AU1448692A (en) Gallic acid derivative, and pharmaceutical compositions containing it
HUT60737A (en) Process for producing new 1,4-dihydropyridine derivatives and pharmaceutical compositions comprising same as active ingredient
HU9302821D0 (en) Pharmaceutical compositions containing 3-substituted-2-oxindole-1-carboxamide as medical agent

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees