TW372962B - Pharmaceutical compositions for the prevention, arrest or reversal of atherosclerotic degradation in the arterial walls of a patient
- Google Patents
Pharmaceutical compositions for the prevention, arrest or reversal of atherosclerotic degradation in the arterial walls of a patient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chemical And Pharmaceutical CompanyfiledCriticalRecordati Chemical And Pharmaceutical Company
Application grantedgrantedCritical
Publication of TW372962BpublicationCriticalpatent/TW372962B/en
1,4 dihydropyridines have been found to counter several processes which play a role in the development of atherosclerotic vascular lesions, such as myocytes proliferation and migration, cholesterol metabolism in macrophages and oxidative modification of low density lipoproteins. They are therefore useful in the manufacture of medicaments for preventing, arresting and reversing atherosclerotic degradation in the arterial walls of humans. The preferred 1,4-dihydropyridines for this purpose are lercanidipine, (S)-lercanidipine and (R)-lercanidipine.
TW085108461A1995-07-141996-07-12Pharmaceutical compositions for the prevention, arrest or reversal of atherosclerotic degradation in the arterial walls of a patient
TW372962B
(en)
Use of 1,4-dihydropyridine derivatives in the preparation of a medicament for the prevention and therapy of atherosclerotic degradation of arterial walls and pharmaceutical compositions containing such derivatives