ITMI932468A0 - Nuovi difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Nuovi difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- ITMI932468A0 ITMI932468A0 ITMI932468A ITMI932468A ITMI932468A0 IT MI932468 A0 ITMI932468 A0 IT MI932468A0 IT MI932468 A ITMI932468 A IT MI932468A IT MI932468 A ITMI932468 A IT MI932468A IT MI932468 A0 ITMI932468 A0 IT MI932468A0
- Authority
- IT
- Italy
- Prior art keywords
- diphenylimidazoles
- dyslipidemia
- arteriosclerosis
- useful
- contain
- Prior art date
Links
- 208000032928 Dyslipidaemia Diseases 0.000 title 1
- 208000017170 Lipid metabolism disease Diseases 0.000 title 1
- 208000011775 arteriosclerosis disease Diseases 0.000 title 1
- 208000029078 coronary artery disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI002468A IT1265209B1 (it) | 1993-11-22 | 1993-11-22 | Difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro |
PCT/EP1994/003684 WO1995014673A1 (en) | 1993-11-22 | 1994-11-09 | 4,5-diphenylimidazole derivatives, their preparation and their use as acyl coenzyme a: cholesterol-0-acyl-transferase (acat) inhibitor |
AU80618/94A AU8061894A (en) | 1993-11-22 | 1994-11-09 | 4,5-diphenylimidazole derivatives, their preparation and their use as acyl coenzyme A: cholesterol-0-acyl-transferase (ACAT) inhibitor |
JP7514784A JPH08506122A (ja) | 1993-11-22 | 1994-11-09 | 異常脂肪血症、アテローム性動脈硬化症及び心臓疾患の治療に有効な新規ジフェニルイミダゾール、それらの製造方法、並びにそれらを含む医薬組成物 |
EP94931591A EP0680472A1 (en) | 1993-11-22 | 1994-11-09 | 4,5-diphenylimidazole derivatives, their preparation and their use as acyl coenzyme a: cholesterol-0-acyl-transferase (acat) inhibitor |
CA002154475A CA2154475A1 (en) | 1993-11-22 | 1994-11-09 | 4,5-diphenylimidazole derivatives, their preparation and their use as acyl coenzyme a: cholesterol-0-acyl-transferase (acat) inhibitor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI002468A IT1265209B1 (it) | 1993-11-22 | 1993-11-22 | Difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI932468A0 true ITMI932468A0 (it) | 1993-11-22 |
ITMI932468A1 ITMI932468A1 (it) | 1995-05-22 |
IT1265209B1 IT1265209B1 (it) | 1996-10-31 |
Family
ID=11367238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT93MI002468A IT1265209B1 (it) | 1993-11-22 | 1993-11-22 | Difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0680472A1 (it) |
JP (1) | JPH08506122A (it) |
AU (1) | AU8061894A (it) |
CA (1) | CA2154475A1 (it) |
IT (1) | IT1265209B1 (it) |
WO (1) | WO1995014673A1 (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1182400A (en) * | 1998-11-17 | 2000-06-05 | Fuji Photo Film Co., Ltd. | Heteroarylthio compounds and cancer remedies containing the same |
JPWO2004007464A1 (ja) * | 2002-07-10 | 2005-11-10 | 住友製薬株式会社 | イミダゾール誘導体 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4188397A (en) * | 1978-09-22 | 1980-02-12 | Smithkline Corporation | 2,2-Alkyldiylbis(thio)bis(imidazoles) |
US4716175A (en) * | 1987-02-24 | 1987-12-29 | Warner-Lambert Company | Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase |
IE904450A1 (en) * | 1989-12-11 | 1991-06-19 | Rhone Poulenc Sante | Imidazoles |
EP0505481A1 (en) * | 1989-12-12 | 1992-09-30 | Rhone-Poulenc Sante | 2-substituted 4,5-diphenyl-imidazoles |
AU7066191A (en) * | 1990-01-12 | 1991-08-05 | Rhone-Poulenc Rorer S.A. | 2-substituted 4,5-diphenyl-imidazoles |
GB9005966D0 (en) * | 1990-03-16 | 1990-05-09 | May & Baker Ltd | New compositions of matter |
AU650465B2 (en) * | 1990-07-03 | 1994-06-23 | Yamanouchi Pharmaceutical Co., Ltd. | Bisheterocyclic compound |
IT1248528B (it) * | 1991-06-21 | 1995-01-19 | Pierrel Spa | Derivati di eteri e tioeteri (etero) aromatici aventi attivita` antiiperlipidemica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
GB9115190D0 (en) * | 1991-07-12 | 1991-08-28 | Rhone Poulenc Rorer Ltd | New compositions of matter |
CA2085844A1 (en) * | 1991-12-27 | 1993-06-28 | Nobuyuki Hamanaka | Fused benzeneoxyacetic acid derivatives |
US5310748A (en) * | 1992-05-11 | 1994-05-10 | The Du Pont Merck Pharmaceutical Company | Imidazoles for the treatment of atherosclerosis |
US5364875A (en) * | 1992-05-11 | 1994-11-15 | The Du Pont Merck Pharmaceutical Company | Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis |
-
1993
- 1993-11-22 IT IT93MI002468A patent/IT1265209B1/it active IP Right Grant
-
1994
- 1994-11-09 JP JP7514784A patent/JPH08506122A/ja active Pending
- 1994-11-09 AU AU80618/94A patent/AU8061894A/en not_active Abandoned
- 1994-11-09 EP EP94931591A patent/EP0680472A1/en not_active Withdrawn
- 1994-11-09 CA CA002154475A patent/CA2154475A1/en not_active Abandoned
- 1994-11-09 WO PCT/EP1994/003684 patent/WO1995014673A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT1265209B1 (it) | 1996-10-31 |
ITMI932468A1 (it) | 1995-05-22 |
CA2154475A1 (en) | 1995-06-01 |
JPH08506122A (ja) | 1996-07-02 |
AU8061894A (en) | 1995-06-13 |
WO1995014673A1 (en) | 1995-06-01 |
EP0680472A1 (en) | 1995-11-08 |
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Legal Events
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0001 | Granted |