JPH11507369A - プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液 - Google Patents
プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液Info
- Publication number
- JPH11507369A JPH11507369A JP9502034A JP50203497A JPH11507369A JP H11507369 A JPH11507369 A JP H11507369A JP 9502034 A JP9502034 A JP 9502034A JP 50203497 A JP50203497 A JP 50203497A JP H11507369 A JPH11507369 A JP H11507369A
- Authority
- JP
- Japan
- Prior art keywords
- surfactant
- composition
- liposome
- submicron
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000003860 storage Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/468,791 US5902604A (en) | 1995-06-06 | 1995-06-06 | Submicron liposome suspensions obtained from preliposome lyophilizates |
| US08/468,791 | 1995-06-06 | ||
| PCT/US1996/009830 WO1996039121A1 (en) | 1995-06-06 | 1996-06-06 | Submicron liposome suspensions obtained from preliposome lyophilizates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11507369A true JPH11507369A (ja) | 1999-06-29 |
| JPH11507369A5 JPH11507369A5 (enExample) | 2004-07-29 |
Family
ID=23861262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9502034A Ceased JPH11507369A (ja) | 1995-06-06 | 1996-06-06 | プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US5902604A (enExample) |
| EP (2) | EP1800665A3 (enExample) |
| JP (1) | JPH11507369A (enExample) |
| AU (1) | AU710113B2 (enExample) |
| CA (1) | CA2221341C (enExample) |
| WO (1) | WO1996039121A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012031200A (ja) * | 2004-11-30 | 2012-02-16 | Western Univ Of Health Sciences | 被覆薬物送達製剤 |
| JP2015193629A (ja) * | 2009-06-03 | 2015-11-05 | マヨ、ジョン、チャールズ | 深部組織の痛みを治療するための製剤 |
| US9555051B2 (en) | 2012-03-29 | 2017-01-31 | Sequessome Technology Holdings Limited | Vesicular formulations |
| JP2017510662A (ja) * | 2014-04-08 | 2017-04-13 | アラダイム コーポレーション | 非結核性抗酸菌に対する活性を有するリポソームシプロフロキサシン製剤 |
| JP2017513839A (ja) * | 2014-04-08 | 2017-06-01 | アラダイム コーポレーション | 凍結融解後に薬物ナノ結晶を形成するリポソーム |
| US10744090B2 (en) | 2015-06-30 | 2020-08-18 | Sequessome Technology Holdings Limited | Multiphasic compositions |
| JP2022538865A (ja) * | 2019-06-28 | 2022-09-06 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソーム化アナマイシン前駆体凍結乾燥物の調製 |
| JP2023502253A (ja) * | 2019-11-21 | 2023-01-23 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソームアナマイシンによる肺標的抗癌療法 |
| JP2023523872A (ja) * | 2019-06-28 | 2023-06-08 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソーム化アナマイシンを再構成する方法 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002509102A (ja) * | 1998-01-16 | 2002-03-26 | バイオミラ・ユーエスエイ・インコーポレイテッド | リポマトリックス製剤 |
| AU773515B2 (en) * | 1999-02-08 | 2004-05-27 | Alza Corporation | Method for controlling liposome size |
| WO2001032145A1 (en) * | 1999-10-29 | 2001-05-10 | Board Of Regents, The University Of Texas System | Method of cancer treatment |
| EP1138312A1 (de) * | 2000-03-28 | 2001-10-04 | Primacare S.A. | Pro-liposomen |
| US6761901B1 (en) | 2000-05-02 | 2004-07-13 | Enzrel Inc. | Liposome drug delivery |
| US20020007055A1 (en) * | 2000-05-15 | 2002-01-17 | Hirotaka Uchiyama | Compositions comprising cyclodextrin |
| CN1245153C (zh) * | 2002-06-06 | 2006-03-15 | 上海家化联合股份有限公司 | 一种维生素a脂质体及其制备方法 |
| EP1543841A4 (en) * | 2002-08-15 | 2011-03-16 | Yunqing Liu | SOLID PHARMACEUTICAL NANO FORMULATION AND MANUFACTURING METHOD THEREFOR |
| AU2004235781A1 (en) * | 2003-05-02 | 2004-11-18 | Aronex Pharmaceuticals, Inc. | Lipid platinum complexes and methods of use thereof |
| AU2003239511A1 (en) * | 2003-05-20 | 2004-12-13 | Aronex Pharmaceuticals, Inc. | Combination chemotherapy comprising a liposomal platinum complex |
| US20080026045A1 (en) * | 2003-05-20 | 2008-01-31 | Jonathan Lewis | Combination Chemotherapy Comprising a Gemcitabine and a Liposomal Platium Complex |
| WO2004105747A1 (en) * | 2003-05-20 | 2004-12-09 | Aronex Pharmaceuticals, Inc | Combination chemotherapy comprising capecitabine and a liposomal platinum complex |
| CA2526289A1 (en) * | 2003-05-20 | 2004-12-02 | Aronex Pharmaceuticals, Inc. | Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex |
| EP1643972A4 (en) * | 2003-06-27 | 2010-01-20 | Smithkline Beecham Corp | STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD |
| US20060002994A1 (en) * | 2004-03-23 | 2006-01-05 | Thomas James L | Responsive liposomes for ultrasonic drug delivery |
| MX2010005862A (es) * | 2007-11-30 | 2010-11-30 | Endo Pharmaceuticals Solutions | Composiciones intravesicales con valrubicina para el tratamiento del cancer de vejiga. |
| US9687550B2 (en) | 2009-12-07 | 2017-06-27 | Arbutus Biopharma Corporation | Compositions for nucleic acid delivery |
| AU2014340568B2 (en) * | 2013-10-22 | 2017-02-02 | Aradigm Corporation | Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile |
| US20160120806A1 (en) * | 2014-04-08 | 2016-05-05 | Aradigm Corporation | Nanocrystals formed in a microenvironment |
| PE20181445A1 (es) * | 2016-01-07 | 2018-09-12 | Univ Western Health Sciences | Formulaciones para el tratamiento del cancer de vejiga |
| AU2017382281B2 (en) | 2016-12-22 | 2024-07-11 | Genentech, Inc. | Methods and formulations for reducing reconstitution time of lyophilized polypeptides |
| US11458092B2 (en) * | 2018-12-14 | 2022-10-04 | NuVessl, Inc. | Composition with enhanced passenger molecule loading |
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| GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
| US4201773A (en) * | 1978-07-26 | 1980-05-06 | The United States Of America As Represented By The Department Of Health, Education And Welfare | 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone |
| US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| BG38660A1 (en) * | 1983-01-11 | 1986-02-14 | Petkov | Machine for hydroplastic processing of tube items |
| JPS6058915A (ja) * | 1983-09-12 | 1985-04-05 | Fujisawa Pharmaceut Co Ltd | 薬物含有脂質小胞体製剤 |
| JPS60155109A (ja) * | 1984-01-23 | 1985-08-15 | Terumo Corp | リポソ−ム製剤 |
| US4537882A (en) * | 1984-05-10 | 1985-08-27 | Ohio State University | 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same |
| CA1264668A (en) * | 1984-06-20 | 1990-01-23 | Pieter R. Cullis | Extrusion techniques for producing liposomes |
| ZW3385A1 (en) * | 1985-03-01 | 1986-09-24 | David John Fluck | Liposomes,process for their preparation and compositions containing them |
| US4975282A (en) * | 1985-06-26 | 1990-12-04 | The Liposome Company, Inc. | Multilamellar liposomes having improved trapping efficiencies |
| GB8516859D0 (en) | 1985-07-03 | 1985-08-07 | Secretary Trade Ind Brit | Cam follower mechanisms |
| DE3689769T2 (de) * | 1985-07-05 | 1994-07-21 | Liposome Co Inc | Multilamellare liposome mit verbesserter einschliessungswirkung. |
| JPS6295134A (ja) * | 1985-10-21 | 1987-05-01 | Nippon Saafuakutanto Kogyo Kk | リポソ−ムの製造法 |
| US4812312A (en) * | 1987-03-03 | 1989-03-14 | Board Of Regents Of The University Of Texas System | Liposome-incorporated nystatin |
| NZ223660A (en) * | 1987-03-05 | 1990-11-27 | Liposome Co Inc | Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity |
| US4911928A (en) * | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US4855090A (en) * | 1987-03-13 | 1989-08-08 | Micro-Pak, Inc. | Method of producing high aqueous volume multilamellar vesicles |
| US5811119A (en) * | 1987-05-19 | 1998-09-22 | Board Of Regents, The University Of Texas | Formulation and use of carotenoids in treatment of cancer |
| US4863739A (en) * | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
| US4950432A (en) * | 1987-10-16 | 1990-08-21 | Board Of Regents, The University Of Texas System | Polyene microlide pre-liposomal powders |
| US5178875A (en) * | 1991-01-14 | 1993-01-12 | The Board Of Regents, The University Of Texas System | Liposomal-polyene preliposomal powder and method for its preparation |
| AU608415B2 (en) * | 1988-01-19 | 1991-03-28 | University Of Texas System, The | Esters of 3'-deaminodoxorubicin, liposomal compositions thereof |
| CA1335077C (en) * | 1988-02-08 | 1995-04-04 | Henri Isliker | Process for the manufacture of apolipoproteins from human blood plasma or serum |
| CA1340241C (en) * | 1988-06-08 | 1998-12-15 | Fountain Pharmaceuticals, Inc. | Method for marking solvent dilution microcarriers |
| US4999199A (en) * | 1988-11-10 | 1991-03-12 | Board Of Regents, The University Of Texas System | Pharmaceutical formulations: liposomes incorporating aromatic polyene antibiotics |
| US5032404A (en) * | 1989-02-23 | 1991-07-16 | Board Of Regents, The University Of Texas System | Lipsome-incorporation of polyenes |
| US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
| JPH06183953A (ja) * | 1991-06-24 | 1994-07-05 | Nippon Oil & Fats Co Ltd | 混合脂質膜小胞 |
| JPH06293615A (ja) * | 1992-08-25 | 1994-10-21 | Nippon Oil & Fats Co Ltd | 混合脂質膜小胞を含有する化粧品 |
| JPH06227966A (ja) * | 1993-01-29 | 1994-08-16 | Advanced Sukin Res Kenkyusho:Kk | 温度感受性リポソーム製剤 |
| FR2700954B1 (fr) * | 1993-01-29 | 1995-04-28 | Eve International Sa | Composition cosmétique à action réparatrice et protectrice des cheveux secs et très secs. |
| DE4306475A1 (de) * | 1993-03-02 | 1994-09-08 | Ensenat Pedro Gonzalez | Liposomen, enthaltend Chlorhexidindiacetat oder Chlorhexidindigluconat |
| EP0706374B1 (en) * | 1993-06-30 | 1997-12-10 | Genentech, Inc. | Method for preparing liposomes |
| US5820880A (en) * | 1995-06-07 | 1998-10-13 | The United States Of America As Represented By The Secretary Of The Army | Liposomal formulation |
-
1995
- 1995-06-06 US US08/468,791 patent/US5902604A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 EP EP07004127A patent/EP1800665A3/en not_active Withdrawn
- 1996-06-06 CA CA002221341A patent/CA2221341C/en not_active Expired - Fee Related
- 1996-06-06 EP EP96918419A patent/EP0831781A1/en not_active Withdrawn
- 1996-06-06 WO PCT/US1996/009830 patent/WO1996039121A1/en not_active Ceased
- 1996-06-06 JP JP9502034A patent/JPH11507369A/ja not_active Ceased
- 1996-06-06 AU AU61087/96A patent/AU710113B2/en not_active Ceased
-
1998
- 1998-07-24 US US09/122,427 patent/US7238366B1/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012031200A (ja) * | 2004-11-30 | 2012-02-16 | Western Univ Of Health Sciences | 被覆薬物送達製剤 |
| JP2015193629A (ja) * | 2009-06-03 | 2015-11-05 | マヨ、ジョン、チャールズ | 深部組織の痛みを治療するための製剤 |
| US9555051B2 (en) | 2012-03-29 | 2017-01-31 | Sequessome Technology Holdings Limited | Vesicular formulations |
| JP2017510662A (ja) * | 2014-04-08 | 2017-04-13 | アラダイム コーポレーション | 非結核性抗酸菌に対する活性を有するリポソームシプロフロキサシン製剤 |
| JP2017513839A (ja) * | 2014-04-08 | 2017-06-01 | アラダイム コーポレーション | 凍結融解後に薬物ナノ結晶を形成するリポソーム |
| US10376508B2 (en) | 2014-04-08 | 2019-08-13 | Aradigm Corporation | Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria |
| US11116765B2 (en) | 2014-04-08 | 2021-09-14 | Grifols, S.A. | Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria |
| US10744090B2 (en) | 2015-06-30 | 2020-08-18 | Sequessome Technology Holdings Limited | Multiphasic compositions |
| US11547665B2 (en) | 2015-06-30 | 2023-01-10 | Sequessome Technology Holdings Limited | Multiphasic compositions |
| JP2022538865A (ja) * | 2019-06-28 | 2022-09-06 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソーム化アナマイシン前駆体凍結乾燥物の調製 |
| JP2023523872A (ja) * | 2019-06-28 | 2023-06-08 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソーム化アナマイシンを再構成する方法 |
| JP2023502253A (ja) * | 2019-11-21 | 2023-01-23 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | リポソームアナマイシンによる肺標的抗癌療法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU710113B2 (en) | 1999-09-16 |
| AU6108796A (en) | 1996-12-24 |
| EP0831781A1 (en) | 1998-04-01 |
| WO1996039121A1 (en) | 1996-12-12 |
| CA2221341C (en) | 2009-04-21 |
| EP1800665A3 (en) | 2008-06-04 |
| US5902604A (en) | 1999-05-11 |
| EP1800665A2 (en) | 2007-06-27 |
| CA2221341A1 (en) | 1996-12-12 |
| US7238366B1 (en) | 2007-07-03 |
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