JPH10513358A - ヒト膵臓細胞系:発達と用途 - Google Patents
ヒト膵臓細胞系:発達と用途Info
- Publication number
- JPH10513358A JPH10513358A JP8524289A JP52428996A JPH10513358A JP H10513358 A JPH10513358 A JP H10513358A JP 8524289 A JP8524289 A JP 8524289A JP 52428996 A JP52428996 A JP 52428996A JP H10513358 A JPH10513358 A JP H10513358A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- vector
- oncogenes
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/12—Hepatocyte growth factor [HGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/55—Vector systems having a special element relevant for transcription from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
- C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38689795A | 1995-02-10 | 1995-02-10 | |
US08/386,897 | 1995-02-10 | ||
US08/509,121 | 1995-07-31 | ||
US08/509,121 US5723333A (en) | 1995-02-10 | 1995-07-31 | Human pancreatic cell lines: developments and uses |
PCT/US1996/001055 WO1996024669A1 (fr) | 1995-02-10 | 1996-01-25 | Lignees de cellules pancreatiques humaines: developpements et utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH10513358A true JPH10513358A (ja) | 1998-12-22 |
Family
ID=23527528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8524289A Ceased JPH10513358A (ja) | 1995-02-10 | 1996-01-25 | ヒト膵臓細胞系:発達と用途 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0808364B1 (fr) |
JP (1) | JPH10513358A (fr) |
AT (1) | ATE311466T1 (fr) |
AU (1) | AU716854B2 (fr) |
BR (1) | BR9607081A (fr) |
CA (1) | CA2210685A1 (fr) |
DE (1) | DE69635513T2 (fr) |
WO (1) | WO1996024669A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011034073A1 (fr) * | 2009-09-15 | 2011-03-24 | 国立大学法人東京大学 | Nouveau procédé de production de cellules différenciées |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6110743A (en) * | 1995-02-10 | 2000-08-29 | The Regents Of The University Of California | Development and use of human pancreatic cell lines |
US6110707A (en) * | 1996-01-19 | 2000-08-29 | Board Of Regents, The University Of Texas System | Recombinant expression of proteins from secretory cell lines |
EP1905304A3 (fr) * | 1997-10-09 | 2008-08-13 | Wellstat Biologics Corporation | Traitement de tumeurs avec des virus |
US6132708A (en) * | 1997-10-10 | 2000-10-17 | Oregon Health Sciences University | Liver regeneration using pancreas cells |
DE10039844A1 (de) * | 1999-08-10 | 2001-04-19 | Hepavec Ag Fuer Gentherapie | Kombinationsvektoren für den Gentransfer, Verfahren zu ihrer Herstellung und ihre Verwendung |
GB0005856D0 (en) * | 2000-03-10 | 2000-05-03 | Reneuron Ltd | Genetic constructs |
GB0125773D0 (en) * | 2001-10-26 | 2001-12-19 | Reneuron Ltd | Constructs |
EP3257943B1 (fr) * | 2010-11-02 | 2019-09-11 | Helmholtz-Zentrum für Infektionsforschung GmbH | Procédés et vecteurs pour l'immortalisation de cellules |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989003882A1 (fr) * | 1987-10-09 | 1989-05-05 | Immunex Corporation | Vecteurs retroviraux de transformation de promoteurs multiples |
NZ226750A (en) * | 1987-10-29 | 1990-09-26 | Amrad Corp Ltd | Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene |
AU3102289A (en) * | 1988-03-11 | 1989-09-14 | Dana-Farber Cancer Institute, Inc. | Regulation of expression in mammalian cells |
GB8928884D0 (en) * | 1989-12-21 | 1990-02-28 | Feldmann Marc | Transformed cell lines |
AU7312891A (en) * | 1990-02-12 | 1991-09-03 | Board Of Regents, The University Of Texas System | Satellite cell proliferation in adult skeletal muscle |
EP0455424A3 (en) * | 1990-05-02 | 1992-04-29 | Merck & Co. Inc. | Mammalian inducible promoter cascade system |
IT1264516B1 (it) * | 1993-05-31 | 1996-09-24 | Biotop Sas Di Rita Cassarin | Cellule dendritiche immortalizzate |
US5587309A (en) * | 1994-04-29 | 1996-12-24 | The United States Of America As Represented By The Department Of Health And Human Services | Method of stimulating proliferation and differentiation of human fetal pancreatic cells ex vivo |
-
1996
- 1996-01-25 BR BR9607081A patent/BR9607081A/pt unknown
- 1996-01-25 AU AU47694/96A patent/AU716854B2/en not_active Ceased
- 1996-01-25 EP EP96903692A patent/EP0808364B1/fr not_active Expired - Lifetime
- 1996-01-25 DE DE69635513T patent/DE69635513T2/de not_active Expired - Fee Related
- 1996-01-25 CA CA002210685A patent/CA2210685A1/fr not_active Abandoned
- 1996-01-25 AT AT96903692T patent/ATE311466T1/de not_active IP Right Cessation
- 1996-01-25 JP JP8524289A patent/JPH10513358A/ja not_active Ceased
- 1996-01-25 WO PCT/US1996/001055 patent/WO1996024669A1/fr active IP Right Grant
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011034073A1 (fr) * | 2009-09-15 | 2011-03-24 | 国立大学法人東京大学 | Nouveau procédé de production de cellules différenciées |
JP2015130866A (ja) * | 2009-09-15 | 2015-07-23 | 国立大学法人 東京大学 | 分化細胞の新規製造法 |
JP5791191B2 (ja) * | 2009-09-15 | 2015-10-07 | 国立大学法人 東京大学 | 分化細胞の新規製造法 |
US9200254B2 (en) | 2009-09-15 | 2015-12-01 | The University Of Tokyo | Method for producing differentiated cells |
JP2015213520A (ja) * | 2009-09-15 | 2015-12-03 | 国立大学法人 東京大学 | 分化細胞の新規製造法 |
US10087419B2 (en) | 2009-09-15 | 2018-10-02 | The University Of Tokyo | Method for producing differentiated cells |
Also Published As
Publication number | Publication date |
---|---|
MX9706019A (es) | 1997-11-29 |
WO1996024669A1 (fr) | 1996-08-15 |
EP0808364A1 (fr) | 1997-11-26 |
BR9607081A (pt) | 1997-11-11 |
AU4769496A (en) | 1996-08-27 |
AU716854B2 (en) | 2000-03-09 |
EP0808364B1 (fr) | 2005-11-30 |
EP0808364A4 (fr) | 2001-03-07 |
DE69635513T2 (de) | 2006-08-17 |
DE69635513D1 (de) | 2006-01-05 |
CA2210685A1 (fr) | 1996-08-15 |
ATE311466T1 (de) | 2005-12-15 |
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Legal Events
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