GB0125773D0 - Constructs - Google Patents

Constructs

Info

Publication number
GB0125773D0
GB0125773D0 GBGB0125773.2A GB0125773A GB0125773D0 GB 0125773 D0 GB0125773 D0 GB 0125773D0 GB 0125773 A GB0125773 A GB 0125773A GB 0125773 D0 GB0125773 D0 GB 0125773D0
Authority
GB
United Kingdom
Prior art keywords
constructs
conditionally
intron
transplantation
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0125773.2A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reneuron Ltd
Original Assignee
Reneuron Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reneuron Ltd filed Critical Reneuron Ltd
Priority to GBGB0125773.2A priority Critical patent/GB0125773D0/en
Publication of GB0125773D0 publication Critical patent/GB0125773D0/en
Priority to US10/493,523 priority patent/US20050032213A1/en
Priority to JP2003538379A priority patent/JP4188241B2/en
Priority to AT02777445T priority patent/ATE312933T1/en
Priority to AU2002339063A priority patent/AU2002339063B2/en
Priority to PCT/GB2002/004828 priority patent/WO2003035879A2/en
Priority to EP02777445A priority patent/EP1438410B1/en
Priority to CA002464417A priority patent/CA2464417A1/en
Priority to DE60208066T priority patent/DE60208066T2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Abstract

Recombinant vectors or constructs are prepared comprising a polynucleotide that encodes a conditionally-induced oncogene operably linked to the enhancer element of the second intron of the nestin gene, or a functional fragment thereof. The constructs can be used to produce conditionally immortal cells, for transplantation.
GBGB0125773.2A 2001-10-26 2001-10-26 Constructs Ceased GB0125773D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB0125773.2A GB0125773D0 (en) 2001-10-26 2001-10-26 Constructs
US10/493,523 US20050032213A1 (en) 2001-10-26 2002-10-25 Promoters to control cell differentiation
JP2003538379A JP4188241B2 (en) 2001-10-26 2002-10-25 Promoters that control cell differentiation
AT02777445T ATE312933T1 (en) 2001-10-26 2002-10-25 PROMOTORS FOR CONTROLLING CELL DIFFERENTIATION
AU2002339063A AU2002339063B2 (en) 2001-10-26 2002-10-25 Promoters to control cell differentiation
PCT/GB2002/004828 WO2003035879A2 (en) 2001-10-26 2002-10-25 Promoters to control cell differentiation
EP02777445A EP1438410B1 (en) 2001-10-26 2002-10-25 Promoters to control cell differentiation
CA002464417A CA2464417A1 (en) 2001-10-26 2002-10-25 Promoters to control cell differentiation
DE60208066T DE60208066T2 (en) 2001-10-26 2002-10-25 PROMOTERS FOR CONTROLLING CELL DIFFERENTIATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0125773.2A GB0125773D0 (en) 2001-10-26 2001-10-26 Constructs

Publications (1)

Publication Number Publication Date
GB0125773D0 true GB0125773D0 (en) 2001-12-19

Family

ID=9924615

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0125773.2A Ceased GB0125773D0 (en) 2001-10-26 2001-10-26 Constructs

Country Status (9)

Country Link
US (1) US20050032213A1 (en)
EP (1) EP1438410B1 (en)
JP (1) JP4188241B2 (en)
AT (1) ATE312933T1 (en)
AU (1) AU2002339063B2 (en)
CA (1) CA2464417A1 (en)
DE (1) DE60208066T2 (en)
GB (1) GB0125773D0 (en)
WO (1) WO2003035879A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
WO2005042715A2 (en) 2003-10-28 2005-05-12 Anticancer, Inc. Angiogensis models using nestin-expressing stem cells to image nascent blood vessels
EP1645626B1 (en) 2004-09-30 2007-09-12 Reneuron Limited Cell line
WO2006113534A1 (en) * 2005-04-15 2006-10-26 The Johns Hopkins University Immortilization of cells including neuronal cells
GB0902034D0 (en) 2009-02-06 2009-03-11 Reneuron Ltd Method
AU2011325439B2 (en) 2010-11-02 2015-07-23 Helmholtz-Zentrum Fur Infektionsforschung Gmbh Methods and vectors for cell immortalisation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69635513T2 (en) * 1995-02-10 2006-08-17 The Regents Of The University Of California, Oakland Human Pancreas Cell Lines: Developments and Applications
GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
WO1998037181A2 (en) * 1997-02-20 1998-08-27 Whitehead Institute For Biomedical Research Telomerase catalytic subunit gene and encoded protein
US6303370B1 (en) * 1998-03-24 2001-10-16 Mayo Foundation For Medical Education And Research Tissue-specific regulatory elements
US6399384B1 (en) * 1999-09-17 2002-06-04 Reneuron Limited Conditional immortalization of cells
CN1411470A (en) * 1999-11-19 2003-04-16 冷泉港实验室 Transgenic mice expressing fluorescent protein
WO2001053503A1 (en) * 2000-01-18 2001-07-26 Cornell Research Foundation, Inc. Neural progenitor cells from hippocampal tissue and a method for isolating and purifying them
GB0005856D0 (en) * 2000-03-10 2000-05-03 Reneuron Ltd Genetic constructs

Also Published As

Publication number Publication date
EP1438410B1 (en) 2005-12-14
AU2002339063B2 (en) 2006-10-05
JP2005506089A (en) 2005-03-03
DE60208066D1 (en) 2006-01-19
WO2003035879A2 (en) 2003-05-01
JP4188241B2 (en) 2008-11-26
WO2003035879A3 (en) 2003-09-25
DE60208066T2 (en) 2006-08-03
CA2464417A1 (en) 2003-05-01
EP1438410A2 (en) 2004-07-21
US20050032213A1 (en) 2005-02-10
ATE312933T1 (en) 2005-12-15

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)