JPH10510157A - 特異的配列構成を有する核酸の検出法 - Google Patents

特異的配列構成を有する核酸の検出法

Info

Publication number
JPH10510157A
JPH10510157A JP8517797A JP51779796A JPH10510157A JP H10510157 A JPH10510157 A JP H10510157A JP 8517797 A JP8517797 A JP 8517797A JP 51779796 A JP51779796 A JP 51779796A JP H10510157 A JPH10510157 A JP H10510157A
Authority
JP
Japan
Prior art keywords
nucleic acid
binding
seq
sequence
tba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP8517797A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10510157A5 (enExample
Inventor
スーザン. ウェイニンガー
アーサー エム. ウェイニンガー
Original Assignee
ザ ジェン プール インク.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ ジェン プール インク. filed Critical ザ ジェン プール インク.
Publication of JPH10510157A publication Critical patent/JPH10510157A/ja
Publication of JPH10510157A5 publication Critical patent/JPH10510157A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP8517797A 1994-12-09 1995-12-07 特異的配列構成を有する核酸の検出法 Withdrawn JPH10510157A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/353,476 1994-12-09
US08/353,476 US5871902A (en) 1994-12-09 1994-12-09 Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids
PCT/US1995/015944 WO1996017956A2 (en) 1994-12-09 1995-12-07 Method of detection of nucleic acids with a specific sequence composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006163414A Division JP4598722B2 (ja) 1994-12-09 2006-06-13 特異的配列構成を有する核酸の検出法

Publications (2)

Publication Number Publication Date
JPH10510157A true JPH10510157A (ja) 1998-10-06
JPH10510157A5 JPH10510157A5 (enExample) 2005-08-11

Family

ID=23389290

Family Applications (2)

Application Number Title Priority Date Filing Date
JP8517797A Withdrawn JPH10510157A (ja) 1994-12-09 1995-12-07 特異的配列構成を有する核酸の検出法
JP2006163414A Expired - Fee Related JP4598722B2 (ja) 1994-12-09 2006-06-13 特異的配列構成を有する核酸の検出法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006163414A Expired - Fee Related JP4598722B2 (ja) 1994-12-09 2006-06-13 特異的配列構成を有する核酸の検出法

Country Status (15)

Country Link
US (1) US5871902A (enExample)
EP (2) EP0796344B1 (enExample)
JP (2) JPH10510157A (enExample)
CN (2) CN1936020A (enExample)
AT (1) ATE353372T1 (enExample)
BR (1) BR9509977A (enExample)
CA (1) CA2206127A1 (enExample)
DE (1) DE69535384T2 (enExample)
DK (1) DK0796344T3 (enExample)
ES (1) ES2279516T3 (enExample)
IL (2) IL116321A (enExample)
MX (1) MX9704281A (enExample)
NO (2) NO321557B1 (enExample)
PT (1) PT796344E (enExample)
WO (1) WO1996017956A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005304489A (ja) * 2004-03-24 2005-11-04 Sysmex Corp 標的物質検出用プローブセット及び標的物質検出方法。
JP2006320326A (ja) * 1994-12-09 2006-11-30 Gene Pool Inc 特異的配列構成を有する核酸の検出法
US8114962B2 (en) 1994-12-09 2012-02-14 The Gene Pool, Inc. Method of detection of nucleic acids with a specific sequence composition

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050084885A1 (en) * 1994-01-18 2005-04-21 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
US6140466A (en) 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
GB9824544D0 (en) 1998-11-09 1999-01-06 Medical Res Council Screening system
EP0781331B1 (en) 1994-08-20 2008-09-03 Gendaq Limited Improvements in or relating to binding proteins for recognition of dna
US5853990A (en) 1996-07-26 1998-12-29 Edward E. Winger Real time homogeneous nucleotide assay
EP0941365B1 (en) 1996-10-04 2003-06-25 Dako A/S Novel probes for the detection of mycobacteria
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
US6410248B1 (en) 1998-01-30 2002-06-25 Massachusetts Institute Of Technology General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
AU746454B2 (en) * 1998-03-02 2002-05-02 Massachusetts Institute Of Technology Poly zinc finger proteins with improved linkers
US6270973B1 (en) 1998-03-13 2001-08-07 Promega Corporation Multiplex method for nucleic acid detection
US6391551B1 (en) 1998-03-13 2002-05-21 Promega Corporation Detection of nucleic acid hybrids
US6703211B1 (en) 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
US6312902B1 (en) 1998-03-13 2001-11-06 Promega Corporation Nucleic acid detection
US6270974B1 (en) 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
US6268146B1 (en) 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6335162B1 (en) 1998-03-13 2002-01-01 Promega Corporation Nucleic acid detection
US7090975B2 (en) 1998-03-13 2006-08-15 Promega Corporation Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
US6235480B1 (en) * 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6977154B1 (en) 1998-03-17 2005-12-20 Gendaq Limited Nucleic acid binding proteins
US6287772B1 (en) 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
US6664045B1 (en) 1998-06-18 2003-12-16 Boston Probes, Inc. PNA probes, probe sets, methods and kits pertaining to the detection of microorganisms
US6453242B1 (en) * 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7070934B2 (en) 1999-01-12 2006-07-04 Sangamo Biosciences, Inc. Ligand-controlled regulation of endogenous gene expression
US6599692B1 (en) * 1999-09-14 2003-07-29 Sangamo Bioscience, Inc. Functional genomics using zinc finger proteins
US7013219B2 (en) * 1999-01-12 2006-03-14 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6794136B1 (en) 2000-11-20 2004-09-21 Sangamo Biosciences, Inc. Iterative optimization in the design of binding proteins
US7030215B2 (en) * 1999-03-24 2006-04-18 Sangamo Biosciences, Inc. Position dependent recognition of GNN nucleotide triplets by zinc fingers
US20030104526A1 (en) * 1999-03-24 2003-06-05 Qiang Liu Position dependent recognition of GNN nucleotide triplets by zinc fingers
AU6751800A (en) * 1999-08-13 2001-03-13 Aventis Research And Technologies Gmbh Microelectronic molecular descriptor array devices, methods, procedures, and formats for combinatorial selection of intermolecular ligand binding structures and for drug screening
US6428957B1 (en) 1999-11-08 2002-08-06 Agilent Technologies, Inc. Systems tools and methods of assaying biological materials using spatially-addressable arrays
ATE309536T1 (de) * 1999-12-06 2005-11-15 Sangamo Biosciences Inc Methoden zur verwendung von randomisierten zinkfingerprotein-bibliotheken zur identifizierung von genfunktionen
AU2693501A (en) * 2000-01-24 2001-07-31 Gendaq Ltd Nucleic acid binding polypeptides characterized by flexible linkers connected nucleic acid binding modules
US6235483B1 (en) 2000-01-31 2001-05-22 Agilent Technologies, Inc. Methods and kits for indirect labeling of nucleic acids
DE60141205D1 (de) * 2000-04-03 2010-03-18 Cytyc Corp Nachweis und typisierung des papillomavirus mittels pna-sonden
US20020160952A1 (en) * 2000-08-18 2002-10-31 Kazantsev Aleksey G. Inhibition of protein-protein interaction
AU2002225623A8 (en) * 2000-11-17 2009-07-30 John G Wise Creation and identification of proteins having new dna binding specificities
US7067317B2 (en) * 2000-12-07 2006-06-27 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
AU2884102A (en) * 2000-12-07 2002-06-18 Sangamo Biosciences Inc Regulation of angiogenesis with zinc finger proteins
EP1288292A1 (en) * 2001-08-31 2003-03-05 Leids Universitair Medisch Centrum Long peptides of 22-40 amino acid residues that induce and/or enhance antigen specific immune responses.
EP1353941B1 (en) 2001-01-22 2013-03-13 Sangamo BioSciences, Inc. Modified zinc finger binding proteins
US20040161753A1 (en) * 2001-11-16 2004-08-19 Wise John G. Creation and identification of proteins having new dna binding specificities
US7262054B2 (en) * 2002-01-22 2007-08-28 Sangamo Biosciences, Inc. Zinc finger proteins for DNA binding and gene regulation in plants
CN100507564C (zh) * 2002-04-09 2009-07-01 唐舜荣 改进的通过颗粒结合来检测靶分子的方法
US7361635B2 (en) 2002-08-29 2008-04-22 Sangamo Biosciences, Inc. Simultaneous modulation of multiple genes
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
MX2008012023A (es) * 2006-03-21 2008-10-01 Wyeth Corp Metodos para prevenir y tratar enfermedades amiloidogenicas.
US20070231805A1 (en) * 2006-03-31 2007-10-04 Baynes Brian M Nucleic acid assembly optimization using clamped mismatch binding proteins
WO2007136834A2 (en) * 2006-05-19 2007-11-29 Codon Devices, Inc. Combined extension and ligation for nucleic acid assembly
US9057729B2 (en) * 2006-06-29 2015-06-16 Koninklijke Philips N.V. Vitro method of detecting and/or diagnosing cancer using UV light based DNA image cytometry
US8053191B2 (en) * 2006-08-31 2011-11-08 Westend Asset Clearinghouse Company, Llc Iterative nucleic acid assembly using activation of vector-encoded traits
US8227590B2 (en) * 2006-11-21 2012-07-24 Jawaharlal Nehru Centre For Advanced Scientific Research High sensitivity assay for molecular typing of biological sample, probes and a kit thereof
WO2010002883A2 (en) * 2008-06-30 2010-01-07 Bionanomatrix, Inc. Methods and devices for single-molecule whole genome analysis
CN102597006A (zh) * 2009-09-16 2012-07-18 梅西大学 融合多肽以及其应用
US10207240B2 (en) 2009-11-03 2019-02-19 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
US9216414B2 (en) 2009-11-25 2015-12-22 Gen9, Inc. Microfluidic devices and methods for gene synthesis
WO2011085075A2 (en) 2010-01-07 2011-07-14 Gen9, Inc. Assembly of high fidelity polynucleotides
EP4039363A1 (en) 2010-11-12 2022-08-10 Gen9, Inc. Protein arrays and methods of using and making the same
LT3360963T (lt) 2010-11-12 2020-02-25 Gen9, Inc. Nukleorūgščių sintezės būdai ir įrenginiai
LT3594340T (lt) 2011-08-26 2021-10-25 Gen9, Inc. Kompozicijos ir būdai, skirti nukleorūgščių didelio tikslumo sąrankai
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CN104603286B (zh) 2012-04-24 2020-07-31 Gen9股份有限公司 在体外克隆中分选核酸和多重制备物的方法
EP3483311B8 (en) 2012-06-25 2025-10-29 Ginkgo Bioworks, Inc. Methods for nucleic acid assembly and high throughput sequencing
JP2015536653A (ja) * 2012-11-15 2015-12-24 モレキュラー ディテクション イスラエル リミテッド Pcr反応混合物及びそれを使用する方法
CN105039587A (zh) * 2015-04-20 2015-11-11 广东温氏食品集团股份有限公司 用于检测鸭腺病毒2型的引物对及试剂盒
CN105039586A (zh) * 2015-04-20 2015-11-11 广东温氏食品集团股份有限公司 检测鸭2型腺病毒的引物及试剂盒
AU2019405940A1 (en) 2018-12-21 2021-04-15 Illumina, Inc. Nuclease-based RNA depletion
CN114592022A (zh) * 2022-03-30 2022-06-07 南京大学 一种基于dna模板的长链tna合成方法
CN118160680B (zh) * 2024-04-10 2025-07-22 南昌师范学院 一种利用安义瓦灰鸡生产瓦灰鸡的配套制种方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556643A (en) * 1982-07-26 1985-12-03 Agracetus Assay method and probe for polynucleotide sequences
US4948882A (en) * 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
US4623627A (en) * 1983-08-19 1986-11-18 Cetus Corporation Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same
US4724202A (en) * 1983-12-12 1988-02-09 Molecular Diagnostics, Inc. Use of non-hybridizable nucleic acids for the detection of nucleic acid hybridization
EP0146039A3 (en) * 1983-12-12 1986-08-27 Miles Inc. Hybridization assay with immobilization of hybrids by antihybrid binding
US4777129A (en) * 1983-12-12 1988-10-11 Molecular Diagnostics, Inc. Nucleic acid probe detectable by specific nucleic acid binding protein
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4775619A (en) * 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4751177A (en) * 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
US4794075A (en) * 1985-08-29 1988-12-27 Lifecodes Corporation Method for locating and purifying DNA containing single base mismatches
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US5306614A (en) * 1986-01-22 1994-04-26 Institut Pasteur Methods and kits for diagnosing human immunodeficiency virus type 2(HIV-2)
US5310650A (en) * 1986-09-29 1994-05-10 Abbott Laboratoires Method and device for improved reaction kinetics in nucleic acid hybridizations
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
WO1988006601A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Gene repressors
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
JP2739068B2 (ja) * 1988-09-24 1998-04-08 春馬 川口 Dna固定ミクロスフェア及びそれを用いるdna転写制御因子精製法
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
US5198346A (en) * 1989-01-06 1993-03-30 Protein Engineering Corp. Generation and selection of novel DNA-binding proteins and polypeptides
US5096815A (en) * 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
US5556750A (en) * 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
US5459039A (en) * 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
WO1991006679A1 (en) * 1989-10-24 1991-05-16 Stratagene An improved method for hybridizing nucleic acids using single-stranded nucleic acid binding protein
US5215899A (en) * 1989-11-09 1993-06-01 Miles Inc. Nucleic acid amplification employing ligatable hairpin probe and transcription
US5215882A (en) * 1989-11-30 1993-06-01 Ortho Diagnostic Systems, Inc. Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays
WO1991011534A1 (en) * 1990-01-24 1991-08-08 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce A rapid and sensitive test for detecting hepatitis a virus
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
JPH04222599A (ja) * 1990-04-20 1992-08-12 Syntex Usa Inc 二重受容体ポリヌクレオチド検定方法
AU2028792A (en) * 1991-05-17 1992-12-30 Uab Research Foundation Sequence specific dna binding drugs
EP0519338B1 (en) * 1991-06-20 1996-08-28 F. Hoffmann-La Roche Ag Improved methods for nucleic acid amplification
AU655839B2 (en) * 1991-06-27 1995-01-12 Genelabs Technologies, Inc. Screening assay for the detection of DNA-binding molecules
AU3595493A (en) * 1992-01-28 1993-09-01 President And Fellors Of Harvard College Method for nucleic acid hybridization using single-stranded DNA binding protein
AU3919293A (en) * 1992-03-27 1993-11-08 University Of Maryland At Baltimore Detection of gene mutations with mismatch repair enzymes
JPH05308999A (ja) * 1992-05-08 1993-11-22 Sumitomo Metal Ind Ltd B型肝炎ウイルスpre−C変異の判定法
US5534410A (en) * 1993-01-28 1996-07-09 The Regents Of The University Of California TATA-binding protein associated factors drug screens
US5593834A (en) * 1993-06-17 1997-01-14 The Research Foundation Of State University Of New York Method of preparing DNA sequences with known ligand binding characteristics
US5871902A (en) * 1994-12-09 1999-02-16 The Gene Pool, Inc. Sequence-specific detection of nucleic acid hybrids using a DNA-binding molecule or assembly capable of discriminating perfect hybrids from non-perfect hybrids

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006320326A (ja) * 1994-12-09 2006-11-30 Gene Pool Inc 特異的配列構成を有する核酸の検出法
US8114962B2 (en) 1994-12-09 2012-02-14 The Gene Pool, Inc. Method of detection of nucleic acids with a specific sequence composition
JP2005304489A (ja) * 2004-03-24 2005-11-04 Sysmex Corp 標的物質検出用プローブセット及び標的物質検出方法。

Also Published As

Publication number Publication date
PT796344E (pt) 2007-05-31
DE69535384D1 (de) 2007-03-22
NO972611D0 (no) 1997-06-06
ATE353372T1 (de) 2007-02-15
NO20052968D0 (no) 2005-06-17
MX9704281A (es) 1998-07-31
WO1996017956A3 (en) 1997-07-24
BR9509977A (pt) 1998-06-09
CN1936020A (zh) 2007-03-28
IL116321A0 (en) 1996-03-31
JP2006320326A (ja) 2006-11-30
CN1176663A (zh) 1998-03-18
WO1996017956A2 (en) 1996-06-13
IL150713A (en) 2011-02-28
NO972611L (no) 1997-08-11
EP1820864A2 (en) 2007-08-22
JP4598722B2 (ja) 2010-12-15
DK0796344T3 (da) 2007-06-04
CN1255551C (zh) 2006-05-10
ES2279516T3 (es) 2007-08-16
EP1820864A3 (en) 2008-01-23
EP0796344A1 (en) 1997-09-24
US5871902A (en) 1999-02-16
EP0796344B1 (en) 2007-02-07
IL150713A0 (en) 2003-02-12
CA2206127A1 (en) 1996-06-13
NO20052968L (no) 1997-08-11
NO321557B1 (no) 2006-05-29
DE69535384T2 (de) 2007-09-13
IL116321A (en) 2004-09-27

Similar Documents

Publication Publication Date Title
JPH10510157A (ja) 特異的配列構成を有する核酸の検出法
US8114962B2 (en) Method of detection of nucleic acids with a specific sequence composition
US5800984A (en) Nucleic acid sequence detection by triple helix formation at primer site in amplification reactions
US6048687A (en) Cycling DNA/RNA amplification electrochemiluminescent probe assay
JP4216333B2 (ja) オリゴヌクレオチドの化学結合による核酸検出及び増幅
JP3289089B2 (ja) サンドウィッチハイブリッド化技術によるヌクレオチド配列の検出方法
IE83814B1 (en) Quantification of nucleic acid
US20050202427A1 (en) Dipping test strip assay system and assay method for the detection and/or determination of specific uncleic acid sequences
Gudibande et al. Rapid, non-separation electrochemiluminescent DNA hybridization assays for PCR products, using 3′-labelled oligonucleotide probes
JPH04141099A (ja) 増幅捕捉アッセイ
AU2020394910B2 (en) Method and kit for detection of polynucleotide
JP7313485B2 (ja) 核酸検出用多価核酸ナノ構造体及びこれを用いた高感度核酸探針
US6890712B1 (en) Cycling DNA/RNA amplification electrochemiluminescent probe assay
AU757472B2 (en) Method of detection of nucleic acids with a specific sequence composition
HK1109428A (en) Method of detection of nucleic acids with a specific sequence composition
WO2008004706A1 (fr) Procédé de détection d'une substance cible à l'aide d'un procédé d'amplification de l'acide nucléique, disponible dans des conditions thermostatiques
JPH074275B2 (ja) 核酸を増幅して検出するための方法及び診断試験キット
AU4418996A (en) Method of detection of nucleic acids with a specific sequence composition
AU2007201871A1 (en) Method of detection of nucleic acids with a specific sequence composition
CN116500273A (zh) 一种基于信号转换与核酸多重等温扩增的b7-h3蛋白检测方法
JP2004305092A (ja) ヒトアデノウイルスの定量方法並びにそのためのプライマー及びプローブ
JPH11103894A (ja) Dnaの特異的検出方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20041206

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20051213

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060310

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20060508

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20060614