JPH10338665A5 - - Google Patents

Info

Publication number
JPH10338665A5
JPH10338665A5 JP1998063500A JP6350098A JPH10338665A5 JP H10338665 A5 JPH10338665 A5 JP H10338665A5 JP 1998063500 A JP1998063500 A JP 1998063500A JP 6350098 A JP6350098 A JP 6350098A JP H10338665 A5 JPH10338665 A5 JP H10338665A5
Authority
JP
Japan
Prior art keywords
formula
compound
same meaning
benzyloxy
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998063500A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10338665A (ja
JP4132189B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JPH10338665A publication Critical patent/JPH10338665A/ja
Publication of JPH10338665A5 publication Critical patent/JPH10338665A5/ja
Application granted granted Critical
Publication of JP4132189B2 publication Critical patent/JP4132189B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP06350098A 1997-03-14 1998-03-13 置換されたアミノ化合物及びこれを鎮痛に有効な物質として使用する方法 Expired - Fee Related JP4132189B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19710628 1997-03-14
DE19710628:5 1997-03-14

Publications (3)

Publication Number Publication Date
JPH10338665A JPH10338665A (ja) 1998-12-22
JPH10338665A5 true JPH10338665A5 (https=) 2005-09-08
JP4132189B2 JP4132189B2 (ja) 2008-08-13

Family

ID=7823396

Family Applications (1)

Application Number Title Priority Date Filing Date
JP06350098A Expired - Fee Related JP4132189B2 (ja) 1997-03-14 1998-03-13 置換されたアミノ化合物及びこれを鎮痛に有効な物質として使用する方法

Country Status (28)

Country Link
US (1) US6022895A (https=)
EP (1) EP0864559B1 (https=)
JP (1) JP4132189B2 (https=)
KR (1) KR100579428B1 (https=)
CN (1) CN1243721C (https=)
AR (1) AR010129A1 (https=)
AT (1) ATE218534T1 (https=)
AU (1) AU728501B2 (https=)
CA (1) CA2231975C (https=)
CO (1) CO4940510A1 (https=)
CZ (1) CZ295522B6 (https=)
DE (2) DE19805370A1 (https=)
DK (1) DK0864559T3 (https=)
ES (1) ES2178055T3 (https=)
HU (1) HU226060B1 (https=)
IL (1) IL123647A (https=)
MY (1) MY118828A (https=)
NO (1) NO311128B1 (https=)
NZ (1) NZ329951A (https=)
PE (1) PE59899A1 (https=)
PL (1) PL191727B1 (https=)
PT (1) PT864559E (https=)
RU (1) RU2197474C2 (https=)
SI (1) SI0864559T1 (https=)
SK (1) SK284279B6 (https=)
UA (1) UA56997C2 (https=)
UY (1) UY24919A1 (https=)
ZA (1) ZA982157B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate
DE19963179B4 (de) * 1999-12-27 2009-02-05 Grünenthal GmbH Substituierte 1- und 2-Naphthol-Mannichbasen
DE10033459A1 (de) * 2000-07-10 2002-01-24 Gruenenthal Gmbh Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel
EA006507B1 (ru) 2001-10-15 2005-12-29 Янссен Фармацевтика Н.В. Новые замещенные 4-фенил-4-[1h-имидазол-2-ил] пиперидиновые производные и их применение в качестве селективных непептидных агонистов дельта-опиоидов
DE10206403A1 (de) * 2002-02-14 2003-08-28 Gruenenthal Gmbh Synthese von Beta-Aminoketonen
DE10206405A1 (de) * 2002-02-14 2003-08-28 Gruenenthal Gmbh Synthese von substituierten Carbamidestern
CL2004000754A1 (es) * 2003-04-11 2005-02-25 Janssen Pharmaceutica Nv Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central.
DE10341534A1 (de) * 2003-09-09 2005-03-31 Bayer Chemicals Ag Difluoralkylaromaten
AR045939A1 (es) * 2003-09-25 2005-11-16 Solvay Pharm Bv Derivados de bencimidazolona y quinazolinona como agonistas de los receptores orl 1 humanos
NZ546834A (en) 2003-10-01 2010-03-26 Adolor Corp Spirocyclic heterocyclic derivatives and methods of their use
DE102004030099A1 (de) * 2004-06-22 2006-01-12 Grünenthal GmbH Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren
WO2006023757A2 (en) * 2004-08-19 2006-03-02 University Of Virginia Patent Foundation Novel tricyclic, bicyclic, monocyclic, and acyclic amines as potent sodium channel blocking agents
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
RU2320342C2 (ru) * 2005-07-27 2008-03-27 ГУ Научно-исследовательский институт кардиологии Томского научного центра Сибирского отделения Российской академии медицинских наук, ГУ НИИ кардиологии ТНЦ СО РАМН Антиаритмическое средство
JP5090639B2 (ja) 2005-11-18 2012-12-05 出光興産株式会社 芳香族アミン誘導体及びそれを用いた有機エレクトロルミネッセンス素子
US7576207B2 (en) * 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
TWI401237B (zh) * 2006-07-24 2013-07-11 ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備
WO2008033299A2 (en) * 2006-09-12 2008-03-20 Adolor Corporation Use of n-containing spirocompounds for the enhancement of cognitive function
JP2010519206A (ja) * 2007-02-16 2010-06-03 シンタ ファーマシューティカルズ コーポレーション 炎症及び免疫関連使用のための置換縮合環化合物
WO2012100423A1 (en) * 2011-01-27 2012-08-02 Eli Lilly And Company Analgesic compounds, methods, and formulations
RU2538727C1 (ru) * 2013-11-15 2015-01-10 Закрытое акционерное общество "Институт экспериментальной фармакологии" Анальгетическое средство пептидной структуры на основе тридекапептида, содержащего d-октааргининовый вектор
CN104844471B (zh) * 2015-04-21 2017-05-03 苏州远智医药科技有限公司 一种作为dor受体拮抗剂的化合物
CN109896991B (zh) * 2017-12-08 2020-11-20 苏州远智医药科技有限公司 一种δ阿片受体拮抗剂及其用途和药物组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623394A (https=) *
GB872371A (en) * 1958-07-07 1961-07-05 Univ Kansas Reseach Foundation Benzyl amine compounds and means of obtaining the same
DE1203247B (de) * 1961-10-10 1965-10-21 Koninklijke Pharma Fab Nv Verfahren zur Herstellung von Diphenylalkenyl-aminen sowie deren nicht-toxischen Salzen
FR1578702A (https=) * 1961-10-10 1969-08-22
DE1149002B (de) * 1961-10-19 1963-05-22 Giulini Gmbh Geb Verfahren zur Herstellung von blutdrucksteigernden Salzen von N, N-Dialkyl-2-aethyl-3, 3-diphenyl-propen-(2)-yl-aminen
US3452094A (en) * 1967-07-19 1969-06-24 Geigy Chem Corp N - 2 - phenyl - 2 - (2 - hydroxy - 1 - naphthyl) ethyl-n-substituted amines and salts thereof
RU2005717C1 (ru) * 1989-02-17 1994-01-15 Такеда кемикал-индастриз Лтд Способ получения производных аралкиламинов или их кислотно-аддитивных солей
DE69333527T2 (de) * 1993-02-23 2005-06-16 Brigham & Women's Hospital, Inc., Boston Calciumrezeptoraktive moleküle

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