JPH0826064B2 - ステロイドペルアシルグリコシド類の製法 - Google Patents

ステロイドペルアシルグリコシド類の製法

Info

Publication number
JPH0826064B2
JPH0826064B2 JP5510090A JP51009093A JPH0826064B2 JP H0826064 B2 JPH0826064 B2 JP H0826064B2 JP 5510090 A JP5510090 A JP 5510090A JP 51009093 A JP51009093 A JP 51009093A JP H0826064 B2 JPH0826064 B2 JP H0826064B2
Authority
JP
Japan
Prior art keywords
zinc
tigogenin
reaction
cellobioside
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP5510090A
Other languages
English (en)
Japanese (ja)
Other versions
JPH06510794A (ja
Inventor
アレン，ダグラス，ジョン，エム．
ブッシュ，フランク，ロバート
ランバート，ジョン，フランシス
シャイン，ルシェル，ジェームス
ワリスンキー，スタンレー，ウォルター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPH06510794A publication Critical patent/JPH06510794A/ja
Publication of JPH0826064B2 publication Critical patent/JPH0826064B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP5510090A 1991-11-25 1992-10-15 ステロイドペルアシルグリコシド類の製法 Expired - Lifetime JPH0826064B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79757491A 1991-11-25 1991-11-25
US797.574 1991-11-25
PCT/US1992/008638 WO1993011150A1 (en) 1991-11-25 1992-10-15 Method for making steroidal peracyl glycosides

Publications (2)

Publication Number Publication Date
JPH06510794A JPH06510794A (ja) 1994-12-01
JPH0826064B2 true JPH0826064B2 (ja) 1996-03-13

Family

ID=25171219

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5510090A Expired - Lifetime JPH0826064B2 (ja) 1991-11-25 1992-10-15 ステロイドペルアシルグリコシド類の製法

Country Status (13)

Country Link
EP (1) EP0619822A1 (cs)
JP (1) JPH0826064B2 (cs)
AU (1) AU659506B2 (cs)
CA (1) CA2123684A1 (cs)
FI (1) FI942394L (cs)
HU (1) HUT67035A (cs)
IL (1) IL103797A0 (cs)
MX (1) MX9206761A (cs)
NZ (1) NZ245244A (cs)
PT (1) PT101088A (cs)
TW (1) TW232699B (cs)
WO (1) WO1993011150A1 (cs)
ZA (1) ZA929081B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5563259A (en) * 1992-06-26 1996-10-08 Pfizer Inc. Process for making β-O-cellobiosyl steroid derivatives and trimethyl silyl steroid intermediates used therein
US5606041A (en) * 1992-06-26 1997-02-25 Pfizer Inc. Process for steroidal peracyl glycosides
JPH07504921A (ja) * 1992-06-26 1995-06-01 フアイザー・インコーポレイテツド 高コレステロール血症を治療するためのステロイドグリコシド
JPH08504830A (ja) * 1993-04-28 1996-05-28 フアイザー・インコーポレイテツド スピロスタニルグリコシド結晶質一水塩
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
CA2180148A1 (en) * 1993-12-28 1995-07-06 Michael Paul Deninno Hypocholesterolemic agents
WO1996038466A1 (en) * 1995-05-29 1996-12-05 Pfizer Inc. Steroidal glycosides
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
BR0206654A (pt) 2001-01-26 2004-02-25 Schering Corp Combinações de ativador(es) de receptor ativado por proliferação de peroxisoma (ppar) e inibidor(es) de absorção de esterol e tratamentos para indicações vasculares
WO2002058696A2 (en) 2001-01-26 2002-08-01 Schering Corporation The use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DE60216300T2 (de) 2001-09-21 2007-06-28 Schering Corp. Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7560449B2 (en) 2002-11-06 2009-07-14 Schering Corporation Methods and therapeutic combinations for the treatment of demyelination
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
ES2318274T3 (es) 2003-03-07 2009-05-01 Schering Corporation Compuestos de azetidinona sustituida, formulaciones y uso de los mismos para el tratamiento de hipercolesterolemia.
MXPA05009502A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis

Also Published As

Publication number Publication date
EP0619822A1 (en) 1994-10-19
CA2123684A1 (en) 1993-06-10
HUT67035A (en) 1995-01-30
MX9206761A (es) 1995-01-31
WO1993011150A1 (en) 1993-06-10
TW232699B (cs) 1994-10-21
FI942394A7 (fi) 1994-05-24
NZ245244A (en) 1995-04-27
IL103797A0 (en) 1993-04-04
PT101088A (pt) 1994-02-28
ZA929081B (en) 1994-05-24
FI942394A0 (fi) 1994-05-24
AU2775892A (en) 1993-06-28
AU659506B2 (en) 1995-05-18
JPH06510794A (ja) 1994-12-01
FI942394L (fi) 1994-05-24
HU9401374D0 (en) 1994-08-29

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