JPH082308B2 - ａｒａＢプロモーターを含有する複製可能な発現ビヒクル - Google Patents

ａｒａＢプロモーターを含有する複製可能な発現ビヒクル

Info

Publication number
JPH082308B2
JPH082308B2 JP61500818A JP50081886A JPH082308B2 JP H082308 B2 JPH082308 B2 JP H082308B2 JP 61500818 A JP61500818 A JP 61500818A JP 50081886 A JP50081886 A JP 50081886A JP H082308 B2 JPH082308 B2 JP H082308B2
Authority
JP
Japan
Prior art keywords
gene
polypeptide
cecropin
promoter
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61500818A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62501538A (ja
Inventor
ライ，チウヌー
リー，チヤー‐ホウ
リン，ユン‐ロン
レイ，ダン
ウイルコツクス，ゲイリー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INTAANASHONARU JENETEITSUKU ENG Inc
Original Assignee
INTAANASHONARU JENETEITSUKU ENG Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INTAANASHONARU JENETEITSUKU ENG Inc filed Critical INTAANASHONARU JENETEITSUKU ENG Inc
Publication of JPS62501538A publication Critical patent/JPS62501538A/ja
Publication of JPH082308B2 publication Critical patent/JPH082308B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP61500818A 1985-01-28 1986-01-24 ａｒａＢプロモーターを含有する複製可能な発現ビヒクル Expired - Lifetime JPH082308B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69530985A 1985-01-28 1985-01-28
US79747285A 1985-11-13 1985-11-13
US695309 1985-11-13
US797472 1985-11-13
PCT/US1986/000131 WO1986004356A1 (en) 1985-01-28 1986-01-24 AraB PROMOTERS AND METHOD OF PRODUCING POLYPEPTIDES, INCLUDINN CECROPINS, BY MICROBIOLOGICAL TECHNIQUES

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP6094753A Division JPH0829112B2 (ja) 1985-01-28 1994-05-09 ａｒａＢプロモーター、および微生物学的方法によるセクロピン類を含むポリペプチド類の製造法

Publications (2)

Publication Number Publication Date
JPS62501538A JPS62501538A (ja) 1987-06-25
JPH082308B2 true JPH082308B2 (ja) 1996-01-17

Family

ID=27105550

Family Applications (2)

Application Number Title Priority Date Filing Date
JP61500818A Expired - Lifetime JPH082308B2 (ja) 1985-01-28 1986-01-24 ａｒａＢプロモーターを含有する複製可能な発現ビヒクル
JP6094753A Expired - Lifetime JPH0829112B2 (ja) 1985-01-28 1994-05-09 ａｒａＢプロモーター、および微生物学的方法によるセクロピン類を含むポリペプチド類の製造法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP6094753A Expired - Lifetime JPH0829112B2 (ja) 1985-01-28 1994-05-09 ａｒａＢプロモーター、および微生物学的方法によるセクロピン類を含むポリペプチド類の製造法

Country Status (8)

Country Link
EP (2) EP0460709B1 (enExample)
JP (2) JPH082308B2 (enExample)
KR (1) KR870700095A (enExample)
AT (2) ATE101203T1 (enExample)
DE (2) DE3689598T2 (enExample)
FI (1) FI94774C (enExample)
NO (1) NO175870C (enExample)
WO (1) WO1986004356A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166321A (en) * 1985-01-28 1992-11-24 International Genetic Engineering, Inc. Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria
US5028530A (en) * 1985-01-28 1991-07-02 Xoma Corporation AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques
JPH02502513A (ja) * 1986-07-25 1990-08-16 ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ 病気抵抗体及び害虫抵抗体を植物に組み込む方法並びに植物に組み込まれ該抵抗体の暗号に対応する新規な遺伝子
US5597945A (en) * 1986-07-25 1997-01-28 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Plants genetically enhanced for disease resistance
DE3716957A1 (de) * 1987-05-20 1988-12-01 Boehringer Mannheim Gmbh Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten
CA1327311C (en) * 1987-07-06 1994-03-01 Jesse M. Jaynes Therapeutic antimicrobial polypeptides, their use and methods for preparation
DE3854476T2 (de) * 1987-07-06 1996-04-04 Univ Louisiana State Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.
US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
EP0326419A3 (en) * 1988-01-27 1991-09-25 THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE Vaccines for the protection of animals against hypodermosis
US5631007A (en) * 1990-03-12 1997-05-20 Ciba-Geigy Corporation Anti-pathogenically effective compositions comprising lytic peptides and hydrolytic enzymes
PH30997A (en) * 1990-03-12 1997-12-23 Ciba Geigy Antipathologenically effective compositions comprising lytic peptides and hydrolytic enzymes.
IL114697A0 (en) * 1994-07-22 1995-11-27 Demeter Biotech Ltd Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use
US5589364A (en) * 1994-07-29 1996-12-31 Magainin Pharmaceuticals Inc. Recombinant production of biologically active peptides and proteins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
WO1998011231A1 (en) * 1996-09-10 1998-03-19 The Rockefeller University Highly regulable promoter for heterologous gene expression
EP1259548A1 (en) 2000-02-24 2002-11-27 Eidgenössische Technische Hochschule Zürich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
EP1824980B1 (en) 2004-12-07 2010-04-28 Lonza Ag Rhamnose promoter expression system
ES2776698T3 (es) 2012-12-20 2020-07-31 Purdue Research Foundation Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer
JP7282521B2 (ja) 2016-04-08 2023-05-29 パーデュー・リサーチ・ファウンデイション Ｃａｒ ｔ細胞療法のための方法および組成物
US11649288B2 (en) 2017-02-07 2023-05-16 Seattle Children's Hospital Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
CN112292138A (zh) 2018-01-22 2021-01-29 西雅图儿童医院（Dba西雅图儿童研究所） Car t细胞的使用方法
SG11202007426XA (en) 2018-02-06 2020-09-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
WO2019165237A1 (en) 2018-02-23 2019-08-29 Endocyte, Inc. Sequencing method for car t cell therapy
CN112575047B (zh) * 2020-12-29 2024-06-21 中农颖泰林州生物科园有限公司 一种提高饲料用的抗菌肽天蚕素收率的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4335104A (en) * 1978-08-16 1982-06-15 United Chemical Corporation Anhydrous multi-purpose moisturizing composition
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
US4520016A (en) * 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
US4355104A (en) 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
IL68561A (en) 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS61501186A (ja) * 1983-10-11 1986-06-19 インターナシヨナル　ジネテイツク　エンジニアリング　インコーポレイテツド タウマチン（Ｔｈａｕｍａｔｉｎ）遺伝子の作製と発現

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
「Ｐｒｏｍｏｔｅｒｓ，ＳｔｒｕｃｔｕｒｅａｎｄＦｕｎｃｔｉｏｎ，Ｅｄ．Ｒｏｄｏｒｉｇｕｅｓｅｔａｌ，ＰｒａｅｇａｒＳｃｉｅｎｔｉｆｉｃ，Ｐ．１８３−１９４（１９８２）
Ｇｅｎｅ，Ｖｏｌ．１４，Ｐ．３０９−３１９（１９８１）
Ｎａｔｕｒｅ，Ｖｏｌ．２９２，Ｐ．２４６−２４８（１９８１）
PROMOTERS,STRUCTURE AND FUNCTION=1982 *

Also Published As

Publication number Publication date
EP0460709A1 (en) 1991-12-11
JPS62501538A (ja) 1987-06-25
FI863891A0 (fi) 1986-09-26
DE3650625T2 (de) 1997-10-02
EP0211047A4 (en) 1989-04-24
NO863806D0 (no) 1986-09-24
ATE153377T1 (de) 1997-06-15
ATE101203T1 (de) 1994-02-15
JPH0829112B2 (ja) 1996-03-27
EP0460709B1 (en) 1997-05-21
EP0211047B1 (en) 1994-02-02
NO863806L (no) 1986-11-19
DE3689598T2 (de) 1994-06-30
WO1986004356A1 (en) 1986-07-31
DE3650625D1 (de) 1997-06-26
NO175870C (no) 1994-12-21
KR870700095A (ko) 1987-02-28
NO175870B (enExample) 1994-09-12
EP0211047A1 (en) 1987-02-25
DE3689598D1 (de) 1994-03-17
FI94774C (fi) 1995-10-25
FI863891L (fi) 1986-09-26
JPH0767684A (ja) 1995-03-14
FI94774B (fi) 1995-07-14

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