JPH0822849B2 - カルバモイル誘導体 - Google Patents

カルバモイル誘導体

Info

Publication number
JPH0822849B2
JPH0822849B2 JP2419290A JP41929090A JPH0822849B2 JP H0822849 B2 JPH0822849 B2 JP H0822849B2 JP 2419290 A JP2419290 A JP 2419290A JP 41929090 A JP41929090 A JP 41929090A JP H0822849 B2 JPH0822849 B2 JP H0822849B2
Authority
JP
Japan
Prior art keywords
methyl
acid
ylmethyl
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2419290A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0770061A (ja
Inventor
ロバート・トムズ・ジャコブス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of JPH0770061A publication Critical patent/JPH0770061A/ja
Publication of JPH0822849B2 publication Critical patent/JPH0822849B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2419290A 1989-12-11 1990-12-11 カルバモイル誘導体 Expired - Lifetime JPH0822849B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898927981A GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative
GB8927981-4 1989-12-11

Publications (2)

Publication Number Publication Date
JPH0770061A JPH0770061A (ja) 1995-03-14
JPH0822849B2 true JPH0822849B2 (ja) 1996-03-06

Family

ID=10667774

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2419290A Expired - Lifetime JPH0822849B2 (ja) 1989-12-11 1990-12-11 カルバモイル誘導体

Country Status (31)

Country Link
EP (1) EP0432984B1 (OSRAM)
JP (1) JPH0822849B2 (OSRAM)
KR (1) KR100192999B1 (OSRAM)
CN (1) CN1025786C (OSRAM)
AP (1) AP192A (OSRAM)
AT (1) ATE163641T1 (OSRAM)
AU (1) AU642182B2 (OSRAM)
BG (2) BG50606A3 (OSRAM)
CA (1) CA2031897C (OSRAM)
CZ (1) CZ614690A3 (OSRAM)
DE (1) DE69032083T2 (OSRAM)
DK (1) DK0432984T3 (OSRAM)
ES (1) ES2112832T3 (OSRAM)
FI (1) FI95029C (OSRAM)
GB (2) GB8927981D0 (OSRAM)
GR (1) GR3026279T3 (OSRAM)
HR (1) HRP930326B1 (OSRAM)
HU (2) HU210441B (OSRAM)
IE (1) IE904448A1 (OSRAM)
IL (1) IL96621A (OSRAM)
MY (1) MY106363A (OSRAM)
NO (1) NO174198C (OSRAM)
PL (2) PL166516B1 (OSRAM)
PT (1) PT96154B (OSRAM)
RO (1) RO108562B1 (OSRAM)
RU (1) RU2002740C1 (OSRAM)
SI (1) SI9012330A (OSRAM)
SK (1) SK278528B6 (OSRAM)
TW (1) TW219329B (OSRAM)
YU (1) YU48218B (OSRAM)
ZA (1) ZA909898B (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2063479T3 (es) * 1990-05-04 1995-01-01 Ciba Geigy Ag Indoles substituidos.
GB9020338D0 (en) * 1990-09-18 1990-10-31 Lilly Industries Ltd Pharmaceutical compounds
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
ES2050611B1 (es) * 1992-10-08 1994-12-16 Ici Plc Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
HUT77130A (hu) * 1994-09-16 1998-03-02 Takeda Chemical Industries Ltd. [1,2,4] Triazolo[1,5-b]piridazin-származékok, eljárás előállításukra, és a vegyületeket tartalmazó gyógyszerkészítmények
US7166638B2 (en) * 2003-05-27 2007-01-23 Nicox S.A. Statin derivatives
ATE499344T1 (de) * 2004-10-12 2011-03-15 Decode Genetics Ehf Peri-substituierte bicyclische sulfonamide gegen arterielle verschlusskrankheit
MX2007010112A (es) * 2005-02-25 2007-10-12 Ono Pharmaceutical Co Compuesto indol y uso del mismo.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524152A (en) * 1982-12-30 1985-06-18 Pennwalt Corporation 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure
GB8623429D0 (en) * 1985-10-17 1986-11-05 Ici America Inc Carboximide derivatives
US4837235A (en) * 1985-10-17 1989-06-06 Ici Americas Inc. Indole and indazole keto sulphones as leukotriene antagonists
MY103259A (en) * 1987-04-15 1993-05-29 Ici America Inc Aliphatic carboxamides
GB8906032D0 (en) * 1988-04-14 1989-04-26 Ici America Inc Hetera-aliphatic carboxamides
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process

Also Published As

Publication number Publication date
SK614690A3 (en) 1997-08-06
AU642182B2 (en) 1993-10-14
GB8927981D0 (en) 1990-02-14
NO905327L (no) 1991-06-12
IL96621A (en) 1994-11-28
GR3026279T3 (en) 1998-06-30
IE904448A1 (en) 1991-06-19
HU908137D0 (en) 1991-06-28
CN1053604A (zh) 1991-08-07
DK0432984T3 (da) 1998-11-30
AP192A (en) 1992-06-30
BG60015B2 (bg) 1993-06-30
JPH0770061A (ja) 1995-03-14
EP0432984A2 (en) 1991-06-19
ZA909898B (en) 1991-08-28
NO174198B (no) 1993-12-20
SI9012330A (en) 1997-12-31
GB2238790B (en) 1993-06-30
CA2031897A1 (en) 1991-06-12
NO905327D0 (no) 1990-12-10
ATE163641T1 (de) 1998-03-15
CZ282068B6 (cs) 1997-05-14
BG50606A3 (bg) 1992-09-15
YU48218B (sh) 1997-08-22
KR100192999B1 (ko) 1999-06-15
KR910011780A (ko) 1991-08-07
SK278528B6 (en) 1997-08-06
PL167449B1 (pl) 1995-09-30
AU6791790A (en) 1991-06-13
CA2031897C (en) 2001-12-18
FI95029B (fi) 1995-08-31
HRP930326B1 (en) 1998-12-31
PL166516B1 (pl) 1995-05-31
EP0432984A3 (en) 1992-04-22
PT96154B (pt) 1998-05-29
MY106363A (en) 1995-05-30
EP0432984B1 (en) 1998-03-04
HRP930326A2 (en) 1996-06-30
HU210441B (en) 1995-04-28
HU210877A9 (en) 1995-09-28
PL288184A1 (en) 1992-04-21
RO108562B1 (ro) 1994-06-30
NO174198C (no) 1994-04-06
PT96154A (pt) 1991-09-30
CZ614690A3 (en) 1997-05-14
DE69032083D1 (de) 1998-04-09
HK1003830A1 (en) 1998-11-06
HUT56345A (en) 1991-08-28
TW219329B (OSRAM) 1994-01-21
GB9026797D0 (en) 1991-01-30
DE69032083T2 (de) 1998-07-16
GB2238790A (en) 1991-06-12
ES2112832T3 (es) 1998-04-16
CN1025786C (zh) 1994-08-31
FI906084A0 (fi) 1990-12-11
IL96621A0 (en) 1991-09-16
RU2002740C1 (ru) 1993-11-15
FI95029C (fi) 1995-12-11
AP9000230A0 (en) 1991-01-31
FI906084L (fi) 1991-06-12
YU233090A (sh) 1993-05-28

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