JPH0794461B2 - クロロセファドロキシル１水化物 - Google Patents

クロロセファドロキシル１水化物

Info

Publication number
JPH0794461B2
JPH0794461B2 JP59255860A JP25586084A JPH0794461B2 JP H0794461 B2 JPH0794461 B2 JP H0794461B2 JP 59255860 A JP59255860 A JP 59255860A JP 25586084 A JP25586084 A JP 25586084A JP H0794461 B2 JPH0794461 B2 JP H0794461B2
Authority
JP
Japan
Prior art keywords
monohydrate
acid
amino
chloro
acetonitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59255860A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60139695A (ja
Inventor
ボーザード ダニエル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JPS60139695A publication Critical patent/JPS60139695A/ja
Publication of JPH0794461B2 publication Critical patent/JPH0794461B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP59255860A 1983-12-06 1984-12-05 クロロセファドロキシル１水化物 Expired - Lifetime JPH0794461B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8319463A FR2555989B1 (fr) 1983-12-06 1983-12-06 Monohydrate de chlorocephadroxyle
FR83-19463 1983-12-06

Publications (2)

Publication Number Publication Date
JPS60139695A JPS60139695A (ja) 1985-07-24
JPH0794461B2 true JPH0794461B2 (ja) 1995-10-11

Family

ID=9294877

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59255860A Expired - Lifetime JPH0794461B2 (ja) 1983-12-06 1984-12-05 クロロセファドロキシル１水化物

Country Status (25)

Country Link
JP (1) JPH0794461B2 ( )
KR (1) KR920001769B1 ( )
AT (1) AT386411B ( )
AU (1) AU567780B2 ( )
BE (1) BE901218A ( )
CA (1) CA1246545A ( )
CH (1) CH662569A5 ( )
CY (1) CY1559A ( )
DE (1) DE3444367A1 ( )
DK (1) DK579984A ( )
ES (1) ES8605279A1 ( )
FI (1) FI81104C ( )
FR (1) FR2555989B1 ( )
GB (1) GB2150931B ( )
GR (1) GR81159B ( )
HK (1) HK72590A ( )
IE (1) IE57832B1 ( )
IT (1) IT1177370B ( )
LU (1) LU85670A1 ( )
MY (1) MY102192A ( )
NL (1) NL8403670A ( )
SE (1) SE8406171L ( )
SG (1) SG48890G ( )
YU (1) YU45221B ( )
ZA (1) ZA849415B ( )

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505697A1 (fr) * 1981-05-12 1982-11-19 Humblot Bernard Unite perfectionnee de soudage electrique

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US516047A (en) * 1894-03-06 Wire bed-bottom
CY773A (en) * 1967-09-05 1975-03-01 Bristol Myers Co Antibacterial agents and a process for the preparation thereof
US3781282A (en) * 1971-01-20 1973-12-25 W Garbrecht Cephalosporin process and product
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
YU39709B (en) * 1972-09-15 1985-04-30 Bristol Myers Co Process for producing cephalosporin
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
JPS5356311A (en) * 1976-10-28 1978-05-22 Toyama Chem Co Ltd Cefalexin monohydrate having novel crystal form and process for preparationof the same
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US4600773A (en) * 1983-12-01 1986-07-15 Eli Lilly And Company Crystalline cephalexin hydrochloride monohydrate

Also Published As

Publication number Publication date
IE57832B1 (en) 1993-04-21
ES8605279A1 (es) 1986-03-16
DK579984D0 (da) 1984-12-05
KR920001769B1 (ko) 1992-03-02
GB2150931A (en) 1985-07-10
AT386411B (de) 1988-08-25
AU3632184A (en) 1985-06-13
JPS60139695A (ja) 1985-07-24
BE901218A (fr) 1985-06-05
CH662569A5 (fr) 1987-10-15
IT8423909A0 (it) 1984-12-05
FR2555989B1 (fr) 1987-02-20
IE843117L (en) 1985-06-06
IT1177370B (it) 1987-08-26
YU207384A (en) 1987-12-31
CY1559A (en) 1991-03-22
ES538235A0 (es) 1986-03-16
GR81159B (en) 1985-04-08
SE8406171L (sv) 1985-06-07
KR850004494A (ko) 1985-07-15
YU45221B (en) 1992-05-28
NL8403670A (nl) 1985-07-01
GB2150931B (en) 1987-07-29
HK72590A (en) 1990-09-21
DE3444367A1 (de) 1985-06-20
SG48890G (en) 1990-08-17
LU85670A1 (fr) 1985-09-12
FI81104C (fi) 1990-09-10
FR2555989A1 (fr) 1985-06-07
FI844756A0 (fi) 1984-12-03
CA1246545A (en) 1988-12-13
SE8406171D0 (sv) 1984-12-05
GB8430753D0 (en) 1985-01-16
IT8423909A1 (it) 1986-06-05
FI844756L (fi) 1985-06-07
ATA386384A (de) 1988-01-15
MY102192A (en) 1992-04-30
ZA849415B (en) 1985-07-31
DE3444367C2 ( ) 1993-04-29
DK579984A (da) 1985-06-07
FI81104B (fi) 1990-05-31
AU567780B2 (en) 1987-12-03

Similar Documents

Publication Publication Date Title
USRE31730E (en) Process for the preparation of the crystalline monohydrate of 7-(D-α-aα-(p-hydroxyphenyl)acetamido)-3-methyl-3-cephem-4-carboxylic acid
US20060149056A1 (en) Stable bioavailable crystalline form of cefdinir and a process for the preparation thereof
US20060149096A1 (en) Process for preparation of 7-[a-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
JPS6150955B2 ( )
US4160863A (en) Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US20070191331A1 (en) Crystalline forms of cefdinir potassium salt
US6894162B2 (en) Intermediates in cephalosporin production
EP0093548B1 (en) Cephalosporin derivatives
JPH0794461B2 (ja) クロロセファドロキシル１水化物
JPH0185A (ja) 新規セフアロスポリン誘導体
US20070191602A1 (en) Crystalline form of cefdinir cesium salt
EP1608661A2 (en) Process for the preparaton of 7-(p-hydroxyphenylglycylamido)cephem compounds
KR810001937B1 (ko) 세파드록실 모노하이드레이트의 제조방법
KR850000611B1 (ko) 6-[d(-)-알파-(4-c₁~c₄)알킬-2,3-디옥소-1-피페라지노 카르보닐아미노)페닐아세트아미도] 페니실란산 제조방법
KR960011780B1 (ko) 세팔로스포린 결정성 수화물의 신규 제조방법
US20060205938A1 (en) Monohydrate solvates of loracarbef
JPH05306288A (ja) セフェムエステル化合物の結晶
JPH0948784A (ja) セフェム誘導体の製造方法
JPS6067482A (ja) セフアロスポリンエステル
JPS63119488A (ja) セフアロスポリン誘導体