JPH0669965B2 - 固体持続放出医薬製剤 - Google Patents
固体持続放出医薬製剤Info
- Publication number
- JPH0669965B2 JPH0669965B2 JP62006312A JP631287A JPH0669965B2 JP H0669965 B2 JPH0669965 B2 JP H0669965B2 JP 62006312 A JP62006312 A JP 62006312A JP 631287 A JP631287 A JP 631287A JP H0669965 B2 JPH0669965 B2 JP H0669965B2
- Authority
- JP
- Japan
- Prior art keywords
- weight
- sustained release
- formulation
- xanthan gum
- release carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000007892 solid unit dosage form Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002522 swelling effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 239000007885 tablet disintegrant Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8601204 | 1986-01-18 | ||
| GB868601204A GB8601204D0 (en) | 1986-01-18 | 1986-01-18 | Therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62181227A JPS62181227A (ja) | 1987-08-08 |
| JPH0669965B2 true JPH0669965B2 (ja) | 1994-09-07 |
Family
ID=10591589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62006312A Expired - Lifetime JPH0669965B2 (ja) | 1986-01-18 | 1987-01-16 | 固体持続放出医薬製剤 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5415871A (enExample) |
| EP (1) | EP0234670B1 (enExample) |
| JP (1) | JPH0669965B2 (enExample) |
| KR (1) | KR940011242B1 (enExample) |
| AT (1) | ATE77548T1 (enExample) |
| AU (2) | AU608208B2 (enExample) |
| CA (1) | CA1313133C (enExample) |
| DE (1) | DE3779933T2 (enExample) |
| DK (1) | DK175215B1 (enExample) |
| ES (1) | ES2042541T4 (enExample) |
| FI (1) | FI93608C (enExample) |
| GB (1) | GB8601204D0 (enExample) |
| GR (1) | GR3005796T3 (enExample) |
| IE (1) | IE59333B1 (enExample) |
| IL (1) | IL81281A (enExample) |
| IN (1) | IN164250B (enExample) |
| MX (1) | MX4949A (enExample) |
| MY (1) | MY100721A (enExample) |
| NO (1) | NO173317C (enExample) |
| NZ (1) | NZ218907A (enExample) |
| PH (1) | PH26408A (enExample) |
| PT (1) | PT84133B (enExample) |
| ZA (1) | ZA87173B (enExample) |
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| US5128143A (en) * | 1988-09-19 | 1992-07-07 | Edward Mendell Co., Inc. | Sustained release excipient and tablet formulation |
| US5009895A (en) * | 1990-02-02 | 1991-04-23 | Merck & Co., Inc. | Sustained release with high and low viscosity HPMC |
| IT1250483B (it) * | 1990-08-30 | 1995-04-07 | Eurand Int | Sistema di ritardo a matrice multipla |
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| DE4140183C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Flurbiprofen enthaltendes Arzneimittel |
| DE4140179C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Akutform für ein Ibuprofen enthaltendes Arzneimittel |
| DE4140192C2 (de) * | 1991-12-05 | 1996-02-29 | Alfatec Pharma Gmbh | Sol-gesteuerte Thermokolloidmatrix auf Gelatinebasis für perorale Retardformen |
| DE4140172C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Ibuprofen enthaltendes Arzneimittel |
| US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
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| AU5745394A (en) * | 1992-12-30 | 1994-08-15 | Fmc Corporation | Readily available konjac glucomannan sustained release excipient |
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| FR901111A (fr) * | 1943-08-31 | 1945-07-18 | Perfectionnement aux dispositifs de réglage de terrage des charruesbascules | |
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1986
- 1986-01-18 GB GB868601204A patent/GB8601204D0/en active Pending
- 1986-12-31 IE IE342086A patent/IE59333B1/en not_active IP Right Cessation
-
1987
- 1987-01-06 DE DE8787300035T patent/DE3779933T2/de not_active Expired - Lifetime
- 1987-01-06 AT AT87300035T patent/ATE77548T1/de not_active IP Right Cessation
- 1987-01-06 EP EP87300035A patent/EP0234670B1/en not_active Expired - Lifetime
- 1987-01-06 ES ES87300035T patent/ES2042541T4/es not_active Expired - Lifetime
- 1987-01-07 IN IN9/MAS/87A patent/IN164250B/en unknown
- 1987-01-12 ZA ZA87173A patent/ZA87173B/xx unknown
- 1987-01-13 DK DK198700148A patent/DK175215B1/da not_active IP Right Cessation
- 1987-01-13 NZ NZ218907A patent/NZ218907A/xx unknown
- 1987-01-14 MY MYPI87000032A patent/MY100721A/en unknown
- 1987-01-15 MX MX494987A patent/MX4949A/es unknown
- 1987-01-15 FI FI870155A patent/FI93608C/fi not_active IP Right Cessation
- 1987-01-16 NO NO870181A patent/NO173317C/no not_active IP Right Cessation
- 1987-01-16 CA CA000527498A patent/CA1313133C/en not_active Expired - Fee Related
- 1987-01-16 AU AU67625/87A patent/AU608208B2/en not_active Ceased
- 1987-01-16 PH PH34733A patent/PH26408A/en unknown
- 1987-01-16 JP JP62006312A patent/JPH0669965B2/ja not_active Expired - Lifetime
- 1987-01-16 PT PT84133A patent/PT84133B/pt unknown
- 1987-01-16 IL IL81281A patent/IL81281A/xx not_active IP Right Cessation
- 1987-01-17 KR KR1019870000334A patent/KR940011242B1/ko not_active Expired - Fee Related
-
1991
- 1991-04-19 US US07/687,090 patent/US5415871A/en not_active Expired - Lifetime
- 1991-06-28 AU AU79462/91A patent/AU628754B2/en not_active Ceased
-
1992
- 1992-09-24 GR GR920402118T patent/GR3005796T3/el unknown
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