JPH0587050B2 - - Google Patents
Info
- Publication number
- JPH0587050B2 JPH0587050B2 JP1060554A JP6055489A JPH0587050B2 JP H0587050 B2 JPH0587050 B2 JP H0587050B2 JP 1060554 A JP1060554 A JP 1060554A JP 6055489 A JP6055489 A JP 6055489A JP H0587050 B2 JPH0587050 B2 JP H0587050B2
- Authority
- JP
- Japan
- Prior art keywords
- active vitamin
- composition
- present
- active
- polyvinyl acetal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1060554A JPH02240024A (ja) | 1989-03-13 | 1989-03-13 | 活性型ビタミンｄ↓３類製剤用組成物 |
| KR1019900003246A KR900013964A (ko) | 1989-03-13 | 1990-03-12 | 활성형 비타민 d₃류 제제용 조성물 및 이를 함유하는 안정한 활성형 비타민 d₃류 제제의 제조방법 |
| CA002011943A CA2011943A1 (en) | 1989-03-13 | 1990-03-12 | Compositions for the preparation of dosage-form active vitamins d3 and process for preparing stable dosage-form active vitamins d3 by using the same |
| ES90104750T ES2057225T3 (es) | 1989-03-13 | 1990-03-13 | Una composicion para la preparacion de una vitamina d3 activa en forma de dosificacion y su procedimiento de preparacion. |
| EP90104750A EP0387808B1 (en) | 1989-03-13 | 1990-03-13 | Compositions for the preparation of dosage-form active vitamins d3 and process for preparing stable dosage-form active vitamins d3 by using the same |
| DE9090104750T DE69001573T2 (de) | 1989-03-13 | 1990-03-13 | Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung. |
| US08/003,689 US5258375A (en) | 1989-03-13 | 1993-01-13 | Composition for the preparation of dosage-form active vitamins D3 containing polyvinylacetal diethylaminoacetate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1060554A JPH02240024A (ja) | 1989-03-13 | 1989-03-13 | 活性型ビタミンｄ↓３類製剤用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02240024A JPH02240024A (ja) | 1990-09-25 |
| JPH0587050B2 true JPH0587050B2 (en, 2012) | 1993-12-15 |
Family
ID=13145623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1060554A Granted JPH02240024A (ja) | 1989-03-13 | 1989-03-13 | 活性型ビタミンｄ↓３類製剤用組成物 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0387808B1 (en, 2012) |
| JP (1) | JPH02240024A (en, 2012) |
| KR (1) | KR900013964A (en, 2012) |
| CA (1) | CA2011943A1 (en, 2012) |
| DE (1) | DE69001573T2 (en, 2012) |
| ES (1) | ES2057225T3 (en, 2012) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2845342B2 (ja) * | 1990-04-28 | 1999-01-13 | 大正製薬株式会社 | ビタミンｄ▲下３▼誘導体含有固形製剤組成物 |
| JPH04198129A (ja) * | 1990-11-28 | 1992-07-17 | Sumitomo Pharmaceut Co Ltd | 活性型ビタミンｄ↓３類含有組成物 |
| IL103224A (en) * | 1992-09-18 | 1998-08-16 | Teva Pharma | Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3 |
| HUE056937T2 (hu) | 2006-02-03 | 2022-04-28 | Opko Renal Llc | A D-vitamin elégtelenség és hiány kezelése 25-hidroxivitamin D2-vel és 25-hidroxivitamin D3-mal |
| CA2655499C (en) | 2006-06-21 | 2015-10-27 | Proventiv Therapeutics, Llc | Method of treating and preventing secondary hyperparathyroidism_with vitamin d repletion and vitamin d replacemnt therapies |
| US9034860B2 (en) | 2006-12-07 | 2015-05-19 | Daiichi Sankyo Company, Limited | Pharmaceutical composition containing low-substituted hydroxypropyl cellulose |
| JPWO2008072532A1 (ja) * | 2006-12-07 | 2010-03-25 | 第一三共株式会社 | 貯蔵安定性が改善された医薬組成物 |
| WO2008134523A1 (en) | 2007-04-25 | 2008-11-06 | Proventiv Therapeutics, Llc | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| KR20190141269A (ko) | 2007-04-25 | 2019-12-23 | 사이토크로마 인코포레이티드 | 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
| ES2403107T3 (es) | 2007-04-25 | 2013-05-14 | Cytochroma Inc. | Método de tratamiento de insuficiencia y deficiencia de vitamina D |
| US8962239B2 (en) | 2008-04-02 | 2015-02-24 | Opko Renal, Llc | Methods useful for vitamin D deficiency and related disorders |
| CN105796530A (zh) | 2010-03-29 | 2016-07-27 | 赛特克罗公司 | 用于降低甲状旁腺水平的方法和组合物 |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| JP7034595B2 (ja) * | 2016-03-23 | 2022-03-14 | 株式会社ファンケル | ビタミンｄ３安定化組成物 |
| MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
| JP7085105B2 (ja) * | 2016-11-10 | 2022-06-16 | 日産化学株式会社 | ビタミンｄ３誘導体の製剤 |
| TWI784997B (zh) * | 2016-12-28 | 2022-12-01 | 日商中外製藥股份有限公司 | 包含ｅｄ-７１的固體分散體與油分散體的醫藥組合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62149619A (ja) * | 1985-09-05 | 1987-07-03 | Teijin Ltd | 活性型ビタミンｄ３類注射用組成物 |
| JPS6483019A (en) * | 1987-09-25 | 1989-03-28 | Sunstar Inc | Composition used in oral cavity for orthodontic therapy of tooth |
| JPS6425723A (en) * | 1988-07-07 | 1989-01-27 | Teijin Ltd | Production of active type vitamin d3 composition |
| JP2525478B2 (ja) * | 1989-03-01 | 1996-08-21 | 帝人株式会社 | 安定性の改良された活性型ビタミンｄ▲下３▼類固型製剤 |
-
1989
- 1989-03-13 JP JP1060554A patent/JPH02240024A/ja active Granted
-
1990
- 1990-03-12 KR KR1019900003246A patent/KR900013964A/ko not_active Ceased
- 1990-03-12 CA CA002011943A patent/CA2011943A1/en not_active Abandoned
- 1990-03-13 ES ES90104750T patent/ES2057225T3/es not_active Expired - Lifetime
- 1990-03-13 EP EP90104750A patent/EP0387808B1/en not_active Expired - Lifetime
- 1990-03-13 DE DE9090104750T patent/DE69001573T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0387808B1 (en) | 1993-05-12 |
| EP0387808A2 (en) | 1990-09-19 |
| JPH02240024A (ja) | 1990-09-25 |
| DE69001573D1 (de) | 1993-06-17 |
| EP0387808A3 (en) | 1991-04-03 |
| KR900013964A (ko) | 1990-10-22 |
| CA2011943A1 (en) | 1990-09-13 |
| DE69001573T2 (de) | 1993-08-26 |
| ES2057225T3 (es) | 1994-10-16 |
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