JPH053851B2 - - Google Patents

Info

Publication number
JPH053851B2
JPH053851B2 JP60068512A JP6851285A JPH053851B2 JP H053851 B2 JPH053851 B2 JP H053851B2 JP 60068512 A JP60068512 A JP 60068512A JP 6851285 A JP6851285 A JP 6851285A JP H053851 B2 JPH053851 B2 JP H053851B2
Authority
JP
Japan
Prior art keywords
group
isoquinolinesulfonyl
acid
homopiperazine
methylhomopiperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60068512A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61227581A (ja
Inventor
Hiroyoshi Hidaka
Takanori Sone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13375841&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH053851(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asahi Kasei Kogyo KK filed Critical Asahi Kasei Kogyo KK
Priority to JP6851285A priority Critical patent/JPS61227581A/ja
Priority to DE8585116520T priority patent/DE3583287D1/de
Priority to AT85116520T priority patent/ATE64598T1/de
Priority to EP19850116520 priority patent/EP0187371B1/en
Priority to US06813973 priority patent/US4678783B1/en
Publication of JPS61227581A publication Critical patent/JPS61227581A/ja
Publication of JPH053851B2 publication Critical patent/JPH053851B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6851285A 1983-11-04 1985-04-02 血管拡張剤 Granted JPS61227581A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP6851285A JPS61227581A (ja) 1985-04-02 1985-04-02 血管拡張剤
DE8585116520T DE3583287D1 (de) 1984-12-27 1985-12-23 Substituierte isochinolinsulfonyl-verbindungen.
AT85116520T ATE64598T1 (de) 1984-12-27 1985-12-23 Substituierte isochinolinsulfonyl-verbindungen.
EP19850116520 EP0187371B1 (en) 1984-12-27 1985-12-23 Substituted isoquinolinesulfonyl compounds
US06813973 US4678783B1 (en) 1983-11-04 1985-12-27 Substituted isoquinolinesulfonyl compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6851285A JPS61227581A (ja) 1985-04-02 1985-04-02 血管拡張剤

Publications (2)

Publication Number Publication Date
JPS61227581A JPS61227581A (ja) 1986-10-09
JPH053851B2 true JPH053851B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-18

Family

ID=13375841

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6851285A Granted JPS61227581A (ja) 1983-11-04 1985-04-02 血管拡張剤

Country Status (1)

Country Link
JP (1) JPS61227581A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0667926B2 (ja) * 1985-11-12 1994-08-31 旭化成工業株式会社 環状のイソキノリンスルホンアミド誘導体
JP2720348B2 (ja) * 1989-03-30 1998-03-04 旭化成工業株式会社 脳細胞機能障害改善剤
JP2893029B2 (ja) * 1992-08-10 1999-05-17 旭化成工業株式会社 心臓保護剤
JPH0680569A (ja) * 1992-09-03 1994-03-22 Asahi Chem Ind Co Ltd 血小板凝集阻害剤
CN1210521A (zh) * 1996-02-02 1999-03-10 日本新药株式会社 异喹啉衍生物及医药
SI0956865T2 (sl) * 1996-08-12 2011-04-29 Mitsubishi Pharma Corp Zdravila, ki obsegajo inhibitor Rho-kinaze
EP1074545A4 (en) * 1998-04-23 2001-08-22 Hiroyoshi Hidaka ISOCHINOLINE SULPHONAMIDE DERIVATIVES AND MEDICINES CONTAINING IT AS AN ACTIVE INGREDIENT
US6699508B1 (en) * 1998-08-10 2004-03-02 Asahi Kasei Pharma Corporation Sustained release oral preparations of fasudil hydrochloride
CN100438910C (zh) 1999-04-27 2008-12-03 田边三菱制药株式会社 肝脏疾病的预防治疗药
JP4582561B2 (ja) * 2000-10-23 2010-11-17 旭化成ファーマ株式会社 移植による血管病変の発生抑制剤
JP4854070B2 (ja) * 2004-01-29 2012-01-11 旭化成ファーマ株式会社 バイパス術に伴う血管攣縮治療剤
EP1726306B1 (en) * 2004-03-16 2013-10-30 Asahi Kasei Pharma Corporation Fasudil-containing preparation and method of improving stability thereof
ATE423779T1 (de) 2005-04-25 2009-03-15 Western Therapeutics Inst Inc Hochselektiver rho-kinase-inhibitor
EP1905452B1 (en) 2005-07-12 2013-06-19 Kowa Company, Ltd. Agent for prevention or treatment of glaucoma
US8283337B2 (en) 2007-02-23 2012-10-09 Next21 K.K. Therapeutic or prophylactic agent for vasoconstriction
CN103068818B (zh) 2010-08-26 2014-11-19 兴和株式会社 异喹啉衍生物或其盐的新制造方法
WO2019057121A1 (zh) * 2017-09-25 2019-03-28 南京明德新药研发股份有限公司 一种异喹啉磺酰衍生物的晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0227992B2 (ja) * 1982-01-14 1990-06-20 Asahi Kasei Kogyo Kk Isokinorinsuruhonirukagobutsu
JPS57200366A (en) * 1981-06-01 1982-12-08 Asahi Chem Ind Co Ltd Isoquinoline compound
JPS5993054A (ja) * 1982-11-18 1984-05-29 Asahi Chem Ind Co Ltd イソキノリンスルホン酸アミド誘導体

Also Published As

Publication number Publication date
JPS61227581A (ja) 1986-10-09

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term