JP7681520B2 - 変異体核酸を検出するための融解温度法、キットおよびレポータオリゴ - Google Patents

変異体核酸を検出するための融解温度法、キットおよびレポータオリゴ Download PDF

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JP7681520B2
JP7681520B2 JP2021567881A JP2021567881A JP7681520B2 JP 7681520 B2 JP7681520 B2 JP 7681520B2 JP 2021567881 A JP2021567881 A JP 2021567881A JP 2021567881 A JP2021567881 A JP 2021567881A JP 7681520 B2 JP7681520 B2 JP 7681520B2
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nucleotides
nucleotide
reporter oligonucleotide
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コールディング ベンディクセン，カミラ
クロンボーグ エリクセン，サラ
エリザベス ハンセン，エメリ
ベック クリステンセン，ウルフ
コーフォード ピーターセン，ラスムス
リンド マドセン，セシリエ
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ペンタベース エーピーエス
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    • C12Q2600/156—Polymorphic or mutational markers

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JP2021567881A 2019-05-13 2020-05-13 変異体核酸を検出するための融解温度法、キットおよびレポータオリゴ Active JP7681520B2 (ja)

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EP19174084 2019-05-13
EP19174084.4 2019-05-13
PCT/EP2020/063269 WO2020229510A1 (en) 2019-05-13 2020-05-13 Melting temperature methods, kits and reporter oligo for detecting variant nucleic acids

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JP2022533088A JP2022533088A (ja) 2022-07-21
JPWO2020229510A5 JPWO2020229510A5 (https=) 2023-05-22
JP2022533088A5 JP2022533088A5 (https=) 2023-05-22
JP7681520B2 true JP7681520B2 (ja) 2025-05-22

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US (1) US20220205024A1 (https=)
EP (1) EP3969614A1 (https=)
JP (1) JP7681520B2 (https=)
KR (1) KR20220031544A (https=)
CN (1) CN114286865A (https=)
AU (1) AU2020275447B2 (https=)
CA (1) CA3137670A1 (https=)
SG (1) SG11202110814QA (https=)
WO (1) WO2020229510A1 (https=)

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CN114464246B (zh) * 2022-01-19 2023-05-30 华中科技大学同济医学院附属协和医院 基于CovMutt框架检测与遗传性增加相关的突变的方法
KR20260035911A (ko) * 2023-09-08 2026-03-13 주식회사 씨젠 3개의 프로브를 이용하여 타겟 핵산을 검출하는 방법
KR20250091512A (ko) * 2023-12-14 2025-06-23 주식회사 시선바이오머티리얼스 디지털 중합효소연쇄반응 기반 현미부수체 불안정성 진단을 위한 정보제공 방법 및 이를 위한 키트

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003052134A2 (en) 2001-12-18 2003-06-26 Human Genetic Signatures Pty Ltd Oligonucleotides comprising intercalator pseudonucleotide(s) for detection of nucleic acids and mutants hereof
JP2009529337A (ja) 2006-03-16 2009-08-20 ペンタベイス エイピーエス 核酸、メチル化状態及び核酸の突然変異体を検出するための、シグナリングペア及び疎水性ヌクレオチドを含んだオリゴヌクレオチド、ステムレスビーコン
JP2010110235A (ja) 2008-11-04 2010-05-20 Tosoh Corp 核酸プローブを用いた核酸の変異検出方法
WO2018174318A1 (ko) 2017-03-24 2018-09-27 주식회사 시선바이오머티리얼스 양기능성 pna 프로브를 이용한 융해곡선 분석방법, 및 이를 이용한 현미부수체 불안정성의 진단방법 및 현미부수체 불안정성 진단용 키트
JP2018528780A (ja) 2015-09-22 2018-10-04 バイオカルティス エン フェー 短いホモポリマー反復の改良された検出
WO2019011971A1 (en) 2017-07-12 2019-01-17 Institut Curie METHOD FOR DETECTING MUTATION IN A MICROSATELLITE SEQUENCE

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US6031098A (en) * 1997-08-11 2000-02-29 California Institute Of Technology Detection and treatment of duplex polynucleotide damage
SG170028A1 (en) * 2006-02-24 2011-04-29 Callida Genomics Inc High throughput genome sequencing on dna arrays
US20100316608A1 (en) * 2009-06-15 2010-12-16 Vijayaprakash Suppiah Method of Determining A Response To Treatment With Immunomodulatory Composition
JP2011135823A (ja) * 2009-12-28 2011-07-14 Nagoya Univ オリゴヌクレオチドプローブ及びその利用
WO2017045689A1 (en) 2015-09-14 2017-03-23 Pentabase Aps Methods and materials for detection of mutations
JP6967006B2 (ja) * 2016-01-15 2021-11-17 クアンタポール， インコーポレイテッド 低減されたバックグラウンドの光学に基づくナノポア分析

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003052134A2 (en) 2001-12-18 2003-06-26 Human Genetic Signatures Pty Ltd Oligonucleotides comprising intercalator pseudonucleotide(s) for detection of nucleic acids and mutants hereof
JP2009529337A (ja) 2006-03-16 2009-08-20 ペンタベイス エイピーエス 核酸、メチル化状態及び核酸の突然変異体を検出するための、シグナリングペア及び疎水性ヌクレオチドを含んだオリゴヌクレオチド、ステムレスビーコン
JP2010110235A (ja) 2008-11-04 2010-05-20 Tosoh Corp 核酸プローブを用いた核酸の変異検出方法
JP2018528780A (ja) 2015-09-22 2018-10-04 バイオカルティス エン フェー 短いホモポリマー反復の改良された検出
WO2018174318A1 (ko) 2017-03-24 2018-09-27 주식회사 시선바이오머티리얼스 양기능성 pna 프로브를 이용한 융해곡선 분석방법, 및 이를 이용한 현미부수체 불안정성의 진단방법 및 현미부수체 불안정성 진단용 키트
WO2019011971A1 (en) 2017-07-12 2019-01-17 Institut Curie METHOD FOR DETECTING MUTATION IN A MICROSATELLITE SEQUENCE

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AU2020275447B2 (en) 2026-01-29
AU2020275447A1 (en) 2021-10-28
EP3969614A1 (en) 2022-03-23
CA3137670A1 (en) 2020-11-19
CN114286865A (zh) 2022-04-05
US20220205024A1 (en) 2022-06-30
WO2020229510A1 (en) 2020-11-19
JP2022533088A (ja) 2022-07-21
SG11202110814QA (en) 2021-11-29
KR20220031544A (ko) 2022-03-11

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