JP7469293B2 - Ａｇ１０の製剤 - Google Patents

Ａｇ１０の製剤 Download PDF

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JP7469293B2
JP7469293B2 JP2021507989A JP2021507989A JP7469293B2 JP 7469293 B2 JP7469293 B2 JP 7469293B2 JP 2021507989 A JP2021507989 A JP 2021507989A JP 2021507989 A JP2021507989 A JP 2021507989A JP 7469293 B2 JP7469293 B2 JP 7469293B2
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tablet formulation
weight
fillers
tablet
pharma
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JP2021534189A (ja
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ジャーネリウス ジェスパー
マイケル メニング マーク
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エイドス セラピューティクス，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021507989A 2018-08-17 2019-08-16 Ａｇ１０の製剤 Active JP7469293B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024060790A JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

Applications Claiming Priority (3)

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US201862765154P 2018-08-17 2018-08-17
US62/765,154 2018-08-17
PCT/US2019/046789 WO2020037189A1 (en) 2018-08-17 2019-08-16 Formulations of ag10

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JP2024060790A Division JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

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JP2021534189A JP2021534189A (ja) 2021-12-09
JP7469293B2 true JP7469293B2 (ja) 2024-04-16

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JP2024060790A Pending JP2024083460A (ja) 2018-08-17 2024-04-04 Ａｇ１０の製剤

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US (4) US11260047B2 (https=)
EP (2) EP4647068A3 (https=)
JP (2) JP7469293B2 (https=)
KR (1) KR20210046708A (https=)
CN (1) CN112804998A (https=)
AU (2) AU2019321583C1 (https=)
BR (1) BR112020026493A2 (https=)
CA (1) CA3104695A1 (https=)
CL (1) CL2021000289A1 (https=)
DK (1) DK3836920T3 (https=)
EA (1) EA202190561A1 (https=)
ES (1) ES3055121T3 (https=)
FI (1) FI3836920T3 (https=)
HR (1) HRP20251603T1 (https=)
IL (2) IL325404A (https=)
LT (1) LT3836920T (https=)
MA (1) MA53238A (https=)
MX (1) MX2021001761A (https=)
PL (1) PL3836920T3 (https=)
PT (1) PT3836920T (https=)
RS (1) RS67572B1 (https=)
SG (1) SG11202101393PA (https=)
SI (1) SI3836920T1 (https=)
SM (1) SMT202500463T1 (https=)
TW (1) TWI834708B (https=)
UA (1) UA128256C2 (https=)
WO (1) WO2020037189A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116730920A (zh) 2017-02-17 2023-09-12 文涵治疗有限公司 Ag-10的制备方法、其中间体及其盐
TWI817999B (zh) 2018-03-23 2023-10-11 美商文涵治療有限公司 使用ag10治療ttr澱粉樣沉積症之方法
SI3836920T1 (sl) 2018-08-17 2026-02-27 Eidos Therapeutics, Inc. Formulacije AG10
WO2023052652A1 (en) 2021-10-01 2023-04-06 Sandoz Ag Crystalline form of acoramidis hydrochloride
WO2025235883A1 (en) 2024-05-10 2025-11-13 Eidos Therapeutics, Inc. Acoramidis for use in the treatment of renal dysfunction

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