CN112804998A - Ag10的制剂 - Google Patents

Ag10的制剂 Download PDF

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Publication number
CN112804998A
CN112804998A CN201980054507.6A CN201980054507A CN112804998A CN 112804998 A CN112804998 A CN 112804998A CN 201980054507 A CN201980054507 A CN 201980054507A CN 112804998 A CN112804998 A CN 112804998A
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China
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tablet
weight
pharmaceutically acceptable
acceptable salt
fillers
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Pending
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CN201980054507.6A
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Chinese (zh)
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J·杰尼利乌斯
M·M·孟宁
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Eidos Therapeutics Inc
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Eidos Therapeutics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201980054507.6A 2018-08-17 2019-08-16 Ag10的制剂 Pending CN112804998A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862765154P 2018-08-17 2018-08-17
US62/765,154 2018-08-17
PCT/US2019/046789 WO2020037189A1 (en) 2018-08-17 2019-08-16 Formulations of ag10

Publications (1)

Publication Number Publication Date
CN112804998A true CN112804998A (zh) 2021-05-14

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CN201980054507.6A Pending CN112804998A (zh) 2018-08-17 2019-08-16 Ag10的制剂

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EP (2) EP4647068A3 (https=)
JP (2) JP7469293B2 (https=)
KR (1) KR20210046708A (https=)
CN (1) CN112804998A (https=)
AU (2) AU2019321583C1 (https=)
BR (1) BR112020026493A2 (https=)
CA (1) CA3104695A1 (https=)
CL (1) CL2021000289A1 (https=)
DK (1) DK3836920T3 (https=)
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ES (1) ES3055121T3 (https=)
FI (1) FI3836920T3 (https=)
HR (1) HRP20251603T1 (https=)
IL (2) IL325404A (https=)
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MA (1) MA53238A (https=)
MX (1) MX2021001761A (https=)
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SG (1) SG11202101393PA (https=)
SI (1) SI3836920T1 (https=)
SM (1) SMT202500463T1 (https=)
TW (1) TWI834708B (https=)
UA (1) UA128256C2 (https=)
WO (1) WO2020037189A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116730920A (zh) 2017-02-17 2023-09-12 文涵治疗有限公司 Ag-10的制备方法、其中间体及其盐
TWI817999B (zh) 2018-03-23 2023-10-11 美商文涵治療有限公司 使用ag10治療ttr澱粉樣沉積症之方法
SI3836920T1 (sl) 2018-08-17 2026-02-27 Eidos Therapeutics, Inc. Formulacije AG10
WO2023052652A1 (en) 2021-10-01 2023-04-06 Sandoz Ag Crystalline form of acoramidis hydrochloride
WO2025235883A1 (en) 2024-05-10 2025-11-13 Eidos Therapeutics, Inc. Acoramidis for use in the treatment of renal dysfunction

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EP3836920A1 (en) 2021-06-23
MX2021001761A (es) 2021-04-19
WO2020037189A1 (en) 2020-02-20
JP2024083460A (ja) 2024-06-21
RS67572B1 (sr) 2026-01-30
US12005043B2 (en) 2024-06-11
FI3836920T3 (fi) 2025-12-22
PL3836920T3 (pl) 2026-02-23
EP3836920A4 (en) 2022-04-13
JP2021534189A (ja) 2021-12-09
MA53238A (fr) 2022-04-13
SMT202500463T1 (it) 2026-01-12
SG11202101393PA (en) 2021-03-30
LT3836920T (lt) 2026-01-26
ES3055121T3 (en) 2026-02-10
AU2025226697A1 (en) 2025-09-25
KR20210046708A (ko) 2021-04-28
AU2019321583B2 (en) 2025-06-05
CL2021000289A1 (es) 2021-08-27
EP3836920B1 (en) 2025-10-01
TW202021583A (zh) 2020-06-16
US12539290B2 (en) 2026-02-03
CA3104695A1 (en) 2020-02-20
JP7469293B2 (ja) 2024-04-16
AU2019321583C1 (en) 2025-11-27
IL280906B1 (en) 2026-01-01
EP4647068A2 (en) 2025-11-12
PT3836920T (pt) 2025-12-02
HRP20251603T1 (hr) 2026-01-30
US11260047B2 (en) 2022-03-01
US20260097014A1 (en) 2026-04-09
AU2019321583A1 (en) 2021-01-21
IL280906A (en) 2021-04-29
US20200054607A1 (en) 2020-02-20
DK3836920T3 (da) 2025-12-22
SI3836920T1 (sl) 2026-02-27
US20250057811A1 (en) 2025-02-20
UA128256C2 (uk) 2024-05-22
EA202190561A1 (ru) 2021-05-26
EP4647068A3 (en) 2026-02-25
US20220313661A1 (en) 2022-10-06
BR112020026493A2 (pt) 2021-03-23
IL325404A (en) 2026-02-01
NZ774039A (en) 2025-03-28
TWI834708B (zh) 2024-03-11

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