AU2019321583C1 - Formulations of AG10 - Google Patents

Formulations of AG10

Info

Publication number
AU2019321583C1
AU2019321583C1 AU2019321583A AU2019321583A AU2019321583C1 AU 2019321583 C1 AU2019321583 C1 AU 2019321583C1 AU 2019321583 A AU2019321583 A AU 2019321583A AU 2019321583 A AU2019321583 A AU 2019321583A AU 2019321583 C1 AU2019321583 C1 AU 2019321583C1
Authority
AU
Australia
Prior art keywords
tablet formulation
weight
tablet
fillers
microcrystalline cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2019321583A
Other languages
English (en)
Other versions
AU2019321583B2 (en
AU2019321583A1 (en
Inventor
Jesper JERNELIUS
Mark Michael MENNING
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eidos Therapeutics Inc
Original Assignee
Eidos Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eidos Therapeutics Inc filed Critical Eidos Therapeutics Inc
Publication of AU2019321583A1 publication Critical patent/AU2019321583A1/en
Publication of AU2019321583B2 publication Critical patent/AU2019321583B2/en
Priority to AU2025226697A priority Critical patent/AU2025226697A1/en
Application granted granted Critical
Publication of AU2019321583C1 publication Critical patent/AU2019321583C1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2019321583A 2018-08-17 2019-08-16 Formulations of AG10 Active AU2019321583C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025226697A AU2025226697A1 (en) 2018-08-17 2025-09-03 Formulations of AG10

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862765154P 2018-08-17 2018-08-17
US62/765,154 2018-08-17
PCT/US2019/046789 WO2020037189A1 (en) 2018-08-17 2019-08-16 Formulations of ag10

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025226697A Division AU2025226697A1 (en) 2018-08-17 2025-09-03 Formulations of AG10

Publications (3)

Publication Number Publication Date
AU2019321583A1 AU2019321583A1 (en) 2021-01-21
AU2019321583B2 AU2019321583B2 (en) 2025-06-05
AU2019321583C1 true AU2019321583C1 (en) 2025-11-27

Family

ID=69524257

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2019321583A Active AU2019321583C1 (en) 2018-08-17 2019-08-16 Formulations of AG10
AU2025226697A Pending AU2025226697A1 (en) 2018-08-17 2025-09-03 Formulations of AG10

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025226697A Pending AU2025226697A1 (en) 2018-08-17 2025-09-03 Formulations of AG10

Country Status (27)

Country Link
US (4) US11260047B2 (https=)
EP (2) EP4647068A3 (https=)
JP (2) JP7469293B2 (https=)
KR (1) KR20210046708A (https=)
CN (1) CN112804998A (https=)
AU (2) AU2019321583C1 (https=)
BR (1) BR112020026493A2 (https=)
CA (1) CA3104695A1 (https=)
CL (1) CL2021000289A1 (https=)
DK (1) DK3836920T3 (https=)
EA (1) EA202190561A1 (https=)
ES (1) ES3055121T3 (https=)
FI (1) FI3836920T3 (https=)
HR (1) HRP20251603T1 (https=)
IL (2) IL325404A (https=)
LT (1) LT3836920T (https=)
MA (1) MA53238A (https=)
MX (1) MX2021001761A (https=)
PL (1) PL3836920T3 (https=)
PT (1) PT3836920T (https=)
RS (1) RS67572B1 (https=)
SG (1) SG11202101393PA (https=)
SI (1) SI3836920T1 (https=)
SM (1) SMT202500463T1 (https=)
TW (1) TWI834708B (https=)
UA (1) UA128256C2 (https=)
WO (1) WO2020037189A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116730920A (zh) 2017-02-17 2023-09-12 文涵治疗有限公司 Ag-10的制备方法、其中间体及其盐
TWI817999B (zh) 2018-03-23 2023-10-11 美商文涵治療有限公司 使用ag10治療ttr澱粉樣沉積症之方法
SI3836920T1 (sl) 2018-08-17 2026-02-27 Eidos Therapeutics, Inc. Formulacije AG10
WO2023052652A1 (en) 2021-10-01 2023-04-06 Sandoz Ag Crystalline form of acoramidis hydrochloride
WO2025235883A1 (en) 2024-05-10 2025-11-13 Eidos Therapeutics, Inc. Acoramidis for use in the treatment of renal dysfunction

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9913826B2 (en) * 2012-12-21 2018-03-13 The Board Of Trustees Of The Leland Stanford Junior University Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions

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Also Published As

Publication number Publication date
EP3836920A1 (en) 2021-06-23
MX2021001761A (es) 2021-04-19
WO2020037189A1 (en) 2020-02-20
JP2024083460A (ja) 2024-06-21
RS67572B1 (sr) 2026-01-30
US12005043B2 (en) 2024-06-11
FI3836920T3 (fi) 2025-12-22
PL3836920T3 (pl) 2026-02-23
EP3836920A4 (en) 2022-04-13
JP2021534189A (ja) 2021-12-09
MA53238A (fr) 2022-04-13
SMT202500463T1 (it) 2026-01-12
SG11202101393PA (en) 2021-03-30
LT3836920T (lt) 2026-01-26
ES3055121T3 (en) 2026-02-10
AU2025226697A1 (en) 2025-09-25
KR20210046708A (ko) 2021-04-28
AU2019321583B2 (en) 2025-06-05
CL2021000289A1 (es) 2021-08-27
EP3836920B1 (en) 2025-10-01
TW202021583A (zh) 2020-06-16
US12539290B2 (en) 2026-02-03
CA3104695A1 (en) 2020-02-20
JP7469293B2 (ja) 2024-04-16
IL280906B1 (en) 2026-01-01
EP4647068A2 (en) 2025-11-12
PT3836920T (pt) 2025-12-02
HRP20251603T1 (hr) 2026-01-30
US11260047B2 (en) 2022-03-01
US20260097014A1 (en) 2026-04-09
AU2019321583A1 (en) 2021-01-21
IL280906A (en) 2021-04-29
US20200054607A1 (en) 2020-02-20
DK3836920T3 (da) 2025-12-22
SI3836920T1 (sl) 2026-02-27
US20250057811A1 (en) 2025-02-20
UA128256C2 (uk) 2024-05-22
EA202190561A1 (ru) 2021-05-26
EP4647068A3 (en) 2026-02-25
US20220313661A1 (en) 2022-10-06
BR112020026493A2 (pt) 2021-03-23
IL325404A (en) 2026-02-01
CN112804998A (zh) 2021-05-14
NZ774039A (en) 2025-03-28
TWI834708B (zh) 2024-03-11

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