JP7458686B2 - 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 - Google Patents

抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 Download PDF

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JP7458686B2
JP7458686B2 JP2023516174A JP2023516174A JP7458686B2 JP 7458686 B2 JP7458686 B2 JP 7458686B2 JP 2023516174 A JP2023516174 A JP 2023516174A JP 2023516174 A JP2023516174 A JP 2023516174A JP 7458686 B2 JP7458686 B2 JP 7458686B2
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seq
set forth
antibody
cdr
variant
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JP2023541609A (ja
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チェン ワン,
デンニェン リュウ,
フェン リー,
リャン シャオ,
トントン シュエ,
ジュンユー ガー,
ジンイー ワン,
ラ リュウ,
チー レン,
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シチュアン ケルン-バイオテック バイオファーマシューティカル カンパニー リミテッド
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Priority to JP2023138151A priority Critical patent/JP7649827B2/ja
Priority to JP2023138150A priority patent/JP7649826B2/ja
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Priority to JP2024209392A priority patent/JP7784511B2/ja
Priority to JP2025210219A priority patent/JP2026041845A/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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WO2024012541A1 (zh) * 2022-07-14 2024-01-18 百奥泰生物制药股份有限公司 抗Nectin-4抗体药物偶联物及应用
EP4310101A1 (en) * 2022-07-22 2024-01-24 Emergence Therapeutics AG Novel anti-nectin-4 antibodies and antibody-drug conjugates
CN117567620A (zh) * 2023-09-28 2024-02-20 深圳市汉科生物工程有限公司 一种Nectin-4单克隆抗体及其CAR-NK细胞
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CN117986367B (zh) * 2024-04-02 2024-07-16 上海美迪西生物医药股份有限公司 靶点为Nectin-4的抗体及其应用
KR20250177512A (ko) * 2024-06-14 2025-12-24 삼성바이오에피스 주식회사 신규한 항-넥틴-4 항체 및 이의 용도
WO2025261506A1 (zh) * 2024-06-21 2025-12-26 信达生物制药(苏州)有限公司 抗Nectin-4抗体以及其用途
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