JP7458686B2 - 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 - Google Patents
抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 Download PDFInfo
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- JP7458686B2 JP7458686B2 JP2023516174A JP2023516174A JP7458686B2 JP 7458686 B2 JP7458686 B2 JP 7458686B2 JP 2023516174 A JP2023516174 A JP 2023516174A JP 2023516174 A JP2023516174 A JP 2023516174A JP 7458686 B2 JP7458686 B2 JP 7458686B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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| JP2023138150A JP7649826B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 |
| JP2024209392A JP7784511B2 (ja) | 2020-09-16 | 2024-12-02 | 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 |
| JP2025210219A JP2026041845A (ja) | 2020-09-16 | 2025-12-01 | 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 |
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| JP2023138151A Division JP7649827B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン-4抗体、それを含むコンジュゲート、及びその適用 |
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| EP4496593A1 (en) | 2022-03-23 | 2025-01-29 | Synaffix B.V. | Antibody-conjugates for targeting of tumours expressing nectin-4 |
| WO2024012541A1 (zh) * | 2022-07-14 | 2024-01-18 | 百奥泰生物制药股份有限公司 | 抗Nectin-4抗体药物偶联物及应用 |
| EP4310101A1 (en) * | 2022-07-22 | 2024-01-24 | Emergence Therapeutics AG | Novel anti-nectin-4 antibodies and antibody-drug conjugates |
| CN117567620A (zh) * | 2023-09-28 | 2024-02-20 | 深圳市汉科生物工程有限公司 | 一种Nectin-4单克隆抗体及其CAR-NK细胞 |
| WO2025162492A1 (zh) * | 2024-01-29 | 2025-08-07 | 甘李药业股份有限公司 | 一种连接子、配体-药物偶联物及其医药用途 |
| CN117986367B (zh) * | 2024-04-02 | 2024-07-16 | 上海美迪西生物医药股份有限公司 | 靶点为Nectin-4的抗体及其应用 |
| KR20250177512A (ko) * | 2024-06-14 | 2025-12-24 | 삼성바이오에피스 주식회사 | 신규한 항-넥틴-4 항체 및 이의 용도 |
| WO2025261506A1 (zh) * | 2024-06-21 | 2025-12-26 | 信达生物制药(苏州)有限公司 | 抗Nectin-4抗体以及其用途 |
| WO2026008043A1 (zh) * | 2024-07-04 | 2026-01-08 | 石药集团巨石生物制药有限公司 | 靶向Nectin-4的抗体药物缀合物和免疫检查点抑制剂联合的用途 |
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| WO2019114666A1 (zh) | 2017-12-15 | 2019-06-20 | 四川科伦博泰生物医药股份有限公司 | 生物活性物偶联物及其制备方法和用途 |
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| JP2019502650A (ja) | 2015-11-23 | 2019-01-31 | シチュアン ケルン−バイオテック バイオファーマシューティカル カンパニー リミテッド | 抗ErbB2抗体−薬物コンジュゲート及びその組成物、そのための調製方法、並びにその適用 |
| JP2020510432A (ja) | 2017-03-02 | 2020-04-09 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Nectin−4への特異性を有する抗体及びその使用 |
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| WO2019114666A1 (zh) | 2017-12-15 | 2019-06-20 | 四川科伦博泰生物医药股份有限公司 | 生物活性物偶联物及其制备方法和用途 |
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