MX2023002805A - Anticuerpo anti-nectina-4, conjugado que lo incluye y aplicacion de los mismos. - Google Patents

Anticuerpo anti-nectina-4, conjugado que lo incluye y aplicacion de los mismos.

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Publication number
MX2023002805A
MX2023002805A MX2023002805A MX2023002805A MX2023002805A MX 2023002805 A MX2023002805 A MX 2023002805A MX 2023002805 A MX2023002805 A MX 2023002805A MX 2023002805 A MX2023002805 A MX 2023002805A MX 2023002805 A MX2023002805 A MX 2023002805A
Authority
MX
Mexico
Prior art keywords
antibody
nectin
application
including same
conjugate including
Prior art date
Application number
MX2023002805A
Other languages
English (en)
Spanish (es)
Inventor
Tongtong Xue
Liang Xiao
Le Liu
Jingyi Wang
Dengnian Liu
Cheng Wang
Fen Li
Junyou Ge
Qi Ren
Original Assignee
Sichuan Kelun Biotech Biopharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Kelun Biotech Biopharmaceutical Co Ltd filed Critical Sichuan Kelun Biotech Biopharmaceutical Co Ltd
Publication of MX2023002805A publication Critical patent/MX2023002805A/es

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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3

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MX2023002805A 2020-09-16 2021-09-06 Anticuerpo anti-nectina-4, conjugado que lo incluye y aplicacion de los mismos. MX2023002805A (es)

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CN117567620A (zh) * 2023-09-28 2024-02-20 深圳市汉科生物工程有限公司 一种Nectin-4单克隆抗体及其CAR-NK细胞
WO2025162492A1 (zh) * 2024-01-29 2025-08-07 甘李药业股份有限公司 一种连接子、配体-药物偶联物及其医药用途
CN117986367B (zh) * 2024-04-02 2024-07-16 上海美迪西生物医药股份有限公司 靶点为Nectin-4的抗体及其应用
KR20250177512A (ko) * 2024-06-14 2025-12-24 삼성바이오에피스 주식회사 신규한 항-넥틴-4 항체 및 이의 용도
WO2025261506A1 (zh) * 2024-06-21 2025-12-26 信达生物制药(苏州)有限公司 抗Nectin-4抗体以及其用途
WO2026008043A1 (zh) * 2024-07-04 2026-01-08 石药集团巨石生物制药有限公司 靶向Nectin-4的抗体药物缀合物和免疫检查点抑制剂联合的用途

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US10675357B2 (en) * 2015-09-09 2020-06-09 INSERM (Institut National de la Santé et de la Recherche Médicale Antibodies having specificity to nectin-4 and uses thereof
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