JP7269875B2 - ピラゾロキノリン誘導体を含有するレビー小体病治療剤 - Google Patents
ピラゾロキノリン誘導体を含有するレビー小体病治療剤 Download PDFInfo
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- JP7269875B2 JP7269875B2 JP2019521251A JP2019521251A JP7269875B2 JP 7269875 B2 JP7269875 B2 JP 7269875B2 JP 2019521251 A JP2019521251 A JP 2019521251A JP 2019521251 A JP2019521251 A JP 2019521251A JP 7269875 B2 JP7269875 B2 JP 7269875B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762513727P | 2017-06-01 | 2017-06-01 | |
| US62/513,727 | 2017-06-01 | ||
| PCT/JP2018/020650 WO2018221551A1 (ja) | 2017-06-01 | 2018-05-30 | ピラゾロキノリン誘導体を含有するレビー小体病治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2018221551A1 JPWO2018221551A1 (ja) | 2020-04-02 |
| JP7269875B2 true JP7269875B2 (ja) | 2023-05-09 |
Family
ID=64456542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521251A Active JP7269875B2 (ja) | 2017-06-01 | 2018-05-30 | ピラゾロキノリン誘導体を含有するレビー小体病治療剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11311530B2 (https=) |
| EP (1) | EP3632438B1 (https=) |
| JP (1) | JP7269875B2 (https=) |
| KR (1) | KR20200010220A (https=) |
| CN (1) | CN110612102A (https=) |
| AU (1) | AU2018278422B2 (https=) |
| BR (1) | BR112019023552A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2018221550A1 (ja) | 2017-06-01 | 2018-12-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピラゾロキノリン誘導体とメマンチンの併用による認知症治療剤 |
| RU2019135834A (ru) | 2017-06-01 | 2021-07-13 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Терапевтическое средство для лечения деменции, представляющее собой комбинацию производного пиразолохинолина и донепезила |
| KR20200010211A (ko) | 2017-06-01 | 2020-01-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Pde9 저해제를 포함하는 약제학적 조성물 |
| WO2023064857A1 (en) | 2021-10-14 | 2023-04-20 | Incyte Corporation | Quinoline compounds as inhibitors of kras |
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| ES2961554T3 (es) | 2024-03-12 |
| IL270357A (https=) | 2020-02-27 |
| BR112019023552A2 (pt) | 2020-06-02 |
| US11311530B2 (en) | 2022-04-26 |
| IL270357B2 (en) | 2024-02-01 |
| TW201902479A (zh) | 2019-01-16 |
| EP3632438B1 (en) | 2023-08-23 |
| AU2018278422B2 (en) | 2022-03-17 |
| MX394435B (es) | 2025-03-12 |
| RU2019135690A (ru) | 2021-07-13 |
| EP3632438A4 (en) | 2020-12-23 |
| MX2019013397A (es) | 2020-02-07 |
| AU2018278422A1 (en) | 2019-11-21 |
| WO2018221551A1 (ja) | 2018-12-06 |
| IL270357B1 (en) | 2023-10-01 |
| TWI784006B (zh) | 2022-11-21 |
| JPWO2018221551A1 (ja) | 2020-04-02 |
| CN110612102A (zh) | 2019-12-24 |
| KR20200010220A (ko) | 2020-01-30 |
| CA3061884A1 (en) | 2019-10-29 |
| RU2019135690A3 (https=) | 2021-08-25 |
| US20200155541A1 (en) | 2020-05-21 |
| EP3632438A1 (en) | 2020-04-08 |
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