JP7125385B2 - Ｔｌｒ７／８アンタゴニストおよびそれらの使用 - Google Patents

Ｔｌｒ７／８アンタゴニストおよびそれらの使用 Download PDF

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JP7125385B2
JP7125385B2 JP2019507303A JP2019507303A JP7125385B2 JP 7125385 B2 JP7125385 B2 JP 7125385B2 JP 2019507303 A JP2019507303 A JP 2019507303A JP 2019507303 A JP2019507303 A JP 2019507303A JP 7125385 B2 JP7125385 B2 JP 7125385B2
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methyl
compound
piperidin
mmol
pharmaceutically acceptable
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JP2019527718A5 (cg-RX-API-DMAC7.html
JP2019527718A (ja
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エー． シェラー，ブライアン
チェン，シャオリン
クレアリー，エスター
ブルガー，ナディア
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Merck Patent GmbH
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Merck Patent GmbH
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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