JP7065776B2 - 口腔内の抗炎症剤として用いるためのプロバイオティクス - Google Patents

口腔内の抗炎症剤として用いるためのプロバイオティクス Download PDF

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JP7065776B2
JP7065776B2 JP2018538221A JP2018538221A JP7065776B2 JP 7065776 B2 JP7065776 B2 JP 7065776B2 JP 2018538221 A JP2018538221 A JP 2018538221A JP 2018538221 A JP2018538221 A JP 2018538221A JP 7065776 B2 JP7065776 B2 JP 7065776B2
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interleukin
product
prevention
inflammation
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JP2019502737A5 (enExample
JP2019502737A (ja
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マルクス ルドルフ ゲッツ
ケルスティン ホルムグレン
ニクラス ラーソン
ベルント フィービヒ
ウィリアム ウェイド
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シムライズ アーゲー
プロビ アクチボラーグ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018538221A 2016-01-19 2017-01-18 口腔内の抗炎症剤として用いるためのプロバイオティクス Active JP7065776B2 (ja)

Priority Applications (1)

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JP2021196237A JP7313418B2 (ja) 2016-01-19 2021-12-02 口腔内の抗炎症剤として用いるためのプロバイオティクス

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16151975.6 2016-01-19
EP16151975 2016-01-19
PCT/EP2017/051005 WO2017125447A1 (en) 2016-01-19 2017-01-18 Probiotics for use as anti-inflammatory agents in the oral cavity

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JP2021196237A Division JP7313418B2 (ja) 2016-01-19 2021-12-02 口腔内の抗炎症剤として用いるためのプロバイオティクス

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JP2019502737A JP2019502737A (ja) 2019-01-31
JP2019502737A5 JP2019502737A5 (enExample) 2020-02-27
JP7065776B2 true JP7065776B2 (ja) 2022-05-12

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JP2021196237A Active JP7313418B2 (ja) 2016-01-19 2021-12-02 口腔内の抗炎症剤として用いるためのプロバイオティクス

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US (1) US11020441B2 (enExample)
EP (1) EP3405205B1 (enExample)
JP (2) JP7065776B2 (enExample)
KR (1) KR102852714B1 (enExample)
CN (1) CN109069556B (enExample)
AU (1) AU2017209868B2 (enExample)
NZ (1) NZ744342A (enExample)
WO (1) WO2017125447A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017209868B2 (en) 2016-01-19 2023-08-03 Probi Ab Probiotics for use as anti-inflammatory agents in the oral cavity
EP3196318A1 (en) 2016-01-19 2017-07-26 Symrise AG Probiotics for altering the composition of oral biofilms
EP3351259A1 (en) 2017-01-18 2018-07-25 Symrise AG Probiotics for aggregation with disease-associated species in the oral cavity
PL3494805T3 (pl) 2017-12-08 2025-10-06 Chr. Hansen HMO GmbH Suszone rozpyłowo tetrasacharydy
ES3039971T3 (en) 2017-12-08 2025-10-28 Chr Hansen Hmo Gmbh Spray-dried 3-fucosyllactose
EP4733390A3 (en) * 2018-05-09 2026-07-15 Kobiolabs, Inc. Lactobacillus paracasei strain and use thereof
WO2020001747A1 (en) * 2018-06-26 2020-01-02 Symrise Ag Lactobacillus plantarum for skin care
GB201908154D0 (en) * 2019-06-07 2019-07-24 Probi Ab Lactobacillus compositions and uses thereof
CN111904985B (zh) * 2020-09-15 2021-10-22 广东南芯医疗科技有限公司 副干酪乳杆菌L.p R3-10在制备预防或治疗口腔炎症性疾病药物中的应用
JP7884920B2 (ja) * 2021-06-30 2026-07-06 サンスター株式会社 乳酸菌含有組成物
CN113881751A (zh) * 2021-09-23 2022-01-04 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 口腔菌液载体的应用
CN113832062B (zh) * 2021-09-27 2022-10-28 微康益生菌(苏州)股份有限公司 一种副干酪乳杆菌lc86及其在预防或治疗龋齿和牙周炎上的应用
CN113712841B (zh) * 2021-11-01 2022-02-11 深圳市萱嘉生物科技有限公司 一种甘油葡萄糖苷在制备口腔护理产品中的应用
JP7814921B2 (ja) * 2021-12-24 2026-02-17 サンスター株式会社 乳酸菌含有組成物
CN114606164B (zh) * 2022-04-08 2024-03-15 云南白药集团股份有限公司 一株副干酪乳杆菌Probio-01及其制备益生菌口腔制剂的用途
CN114796287A (zh) * 2022-06-09 2022-07-29 比菲德(北京)生物科技有限公司 一种可预防龋齿和清新口腔的益生菌粉及其应用
US20240091135A1 (en) * 2022-09-17 2024-03-21 Reshma N. Kheraj Compositions and methods for promoting oral health
CN116694525B (zh) * 2023-06-14 2024-08-06 南昌大学 一株植物乳杆菌及其在制备抑制或缓解或治疗口腔粘膜炎菌剂的应用
CN118141739B (zh) * 2024-03-08 2024-08-02 广州壹选日化科技有限公司 一种美白抗过敏牙膏的制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008502714A (ja) 2004-06-14 2008-01-31 バイオガイア・エイビー 歯肉出血を減少させ、口内炎症を軽減するための乳酸菌の使用
WO2012033151A1 (ja) 2010-09-09 2012-03-15 株式会社明治 炎症を抑制する組成物
JP2014516957A (ja) 2011-05-16 2014-07-17 オルガノバランス メディカル アーゲー 細菌性感冒に対する新規な乳酸菌及びそれを含有する組成物
JP6538286B2 (ja) 2016-01-19 2019-07-03 シムライズ アーゲー 口腔バイオフィルムの組成を変化させるプロバイオティクス

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518615A (en) 1983-08-23 1985-05-21 Warner-Lambert Company Non-adhesive chewing gum base composition
US4721620A (en) 1986-04-01 1988-01-26 Warner-Lambert Company Polyvinylacetate bubble gum base composition
US5093136A (en) 1991-05-08 1992-03-03 Nabisco Brands, Inc. Dual gum base bubble gum
US5266336A (en) 1991-11-12 1993-11-30 Wm. Wrigley Jr. Company High flavor impact non-tack chewing gum with reduced plasticization
US5601858A (en) 1994-12-29 1997-02-11 Warner-Lambert Company Non-stick chewing gum
IT1306716B1 (it) 1999-06-21 2001-10-02 Mendes S U R L Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori.
US8283135B2 (en) * 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
US6986709B2 (en) 2001-09-21 2006-01-17 Igt Gaming device having games with variable game functions
US20040101495A1 (en) 2002-11-27 2004-05-27 Leena Nase Method for improving dental health
EP1634948A1 (en) 2004-09-10 2006-03-15 Basf Aktiengesellschaft Means and methods for preventing and/or treating caries
SE528382C2 (sv) * 2004-10-05 2006-10-31 Probi Ab Probiotiska lactobacillusstammar för förbättrad vaginal hälsa
SE529199C2 (sv) * 2005-07-05 2007-05-29 Probi Ab Förstärkt absorption
EP1934328A1 (en) 2005-09-19 2008-06-25 Basf Se Microorganisms inhibiting the formation of foot malodor
KR101300086B1 (ko) * 2005-10-06 2013-08-30 프로비 아베 자가면역질환의 치료를 위한 락토바실러스의 용도
EP2046352A4 (en) 2006-06-06 2012-03-21 Univ Mcgill Fermented milk product and use thereof
CN101190239B (zh) 2006-11-28 2010-11-03 景岳生物科技股份有限公司 含有类干酪乳杆菌的产品
WO2008074473A2 (en) 2006-12-19 2008-06-26 Basf Se Uses and methods for preventing and/or treating caries caused by mutants streptococci
RU2009133376A (ru) 2007-03-27 2011-05-10 Дзе Проктер Энд Гэмбл Компани (US) Способы и наборы для введения пробиотиков
CN102123604A (zh) 2008-06-24 2011-07-13 Wm.雷格利Jr.公司 益生菌口香糖的制造方法
WO2010064373A1 (ja) 2008-12-04 2010-06-10 国立大学法人広島大学 Il-8阻害剤およびその製造方法
JP2012512171A (ja) 2008-12-16 2012-05-31 ネステク ソシエテ アノニム 改善された口腔健康のための組成物及び方法
ES2778836T3 (es) * 2009-03-05 2020-08-12 Probiotical Spa Cepas de bacterias que tienen una alta actividad antiinflamatoria
DK2455095T3 (en) 2009-07-16 2017-07-24 Univ Hiroshima PROPHYLACTIC, IMPROVING OR THERAPEUTIC AGENT FOR ORAL DISEASES
DE202009011370U1 (de) 2009-08-21 2009-11-19 Dreyer Gmbh Vorrichtung zur Oberflächenbehandlung einer sich bewegenden Kunststoffschicht
DE202009011379U1 (de) 2009-08-24 2010-12-30 Khalifa, Samir Orale Präparate zur Mund- und Zahnpflege und Bekämpfung von Mundgeruch
CN101715908A (zh) 2009-12-11 2010-06-02 江南大学 一种提高益生菌清除微囊藻毒素效率的方法
CN101703179A (zh) 2009-12-11 2010-05-12 江南大学 一种清除食品中微囊藻毒素的方法
DK2364712T3 (da) 2010-03-11 2013-05-21 Kloarys Invest Ltd Topisk, kosmetisk eller farmaceutisk sammensætning, der omfatter probiotiske Lactobacillus-stammer, og anvendelse heraf
EP2420580A1 (en) * 2010-08-18 2012-02-22 AB-Biotics, S.A. Probiotic composition for oral health
JP5904028B2 (ja) 2012-06-19 2016-04-13 ライオン株式会社 乳酸菌及びその培養由来物、ならびにこれらを含有する組成物
CA2783414A1 (en) 2012-07-22 2014-01-22 Integral Medical Inc. Probiotic composition
RU2492851C1 (ru) 2012-08-02 2013-09-20 Сергей Владимирович Кузнецов Способ профилактики и лечения воспаления в ротовой полости после стоматологической хирургической операции
EP2968422A1 (en) 2013-03-14 2016-01-20 Nestec S.A. Lactobacillus plantarum ncc 2936 preparations and oral health
US9587284B2 (en) 2014-02-21 2017-03-07 Asian Probiotics and Prebiotics Ltd. Lactic acid bacterium having immunomodulatory and anti-allergic effects and pharmaceutical composition containing the same
TWI505832B (zh) 2014-02-21 2015-11-01 Genmont Biotech Inc 乳酸菌、其組合物與彼等於治療自體免疫疾病暨其倂發症之用途
US9399048B2 (en) 2014-03-05 2016-07-26 Asian Probiotics And Prebiotics Ltd Lactic acid bacteria and its applications in immunomodulation and anti-inflammation
KR101825667B1 (ko) 2014-09-30 2018-02-06 주식회사 알엔에이 비배당체가 세포내에 축적되어 있는 미생물 제제의 제조방법 및 이에 의해 제조된 미생물 제제
JP2018532696A (ja) 2015-08-25 2018-11-08 カレイド・バイオサイエンシズ・インコーポレイテッド グリカン組成物およびその使用
AU2017209868B2 (en) 2016-01-19 2023-08-03 Probi Ab Probiotics for use as anti-inflammatory agents in the oral cavity
GB201600975D0 (en) * 2016-01-19 2016-03-02 Probi Ab Novel strain of probiotic bacteria and compositions and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008502714A (ja) 2004-06-14 2008-01-31 バイオガイア・エイビー 歯肉出血を減少させ、口内炎症を軽減するための乳酸菌の使用
WO2012033151A1 (ja) 2010-09-09 2012-03-15 株式会社明治 炎症を抑制する組成物
JP2014516957A (ja) 2011-05-16 2014-07-17 オルガノバランス メディカル アーゲー 細菌性感冒に対する新規な乳酸菌及びそれを含有する組成物
JP6538286B2 (ja) 2016-01-19 2019-07-03 シムライズ アーゲー 口腔バイオフィルムの組成を変化させるプロバイオティクス

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biogrowing-comprehensive probiotic solutions provider,Brochure from Biogrowing,2015年06月18日,http://www.slideshare.net/AllenLl12/biogrowing-probiotics-brochure-49535320

Also Published As

Publication number Publication date
EP3405205B1 (en) 2020-07-15
NZ744342A (en) 2022-11-25
KR20180102655A (ko) 2018-09-17
JP7313418B2 (ja) 2023-07-24
KR102852714B1 (ko) 2025-08-29
JP2022031608A (ja) 2022-02-21
EP3405205A1 (en) 2018-11-28
WO2017125447A1 (en) 2017-07-27
AU2017209868A1 (en) 2018-08-02
BR112018014545A2 (pt) 2018-12-11
US11020441B2 (en) 2021-06-01
CN109069556A (zh) 2018-12-21
US20190388485A1 (en) 2019-12-26
JP2019502737A (ja) 2019-01-31
HK1259171A1 (en) 2019-11-29
CN109069556B (zh) 2022-11-25
AU2017209868B2 (en) 2023-08-03

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