JP7017509B2 - がんを治療するための四環式キノロン類似体の併用療法 - Google Patents

がんを治療するための四環式キノロン類似体の併用療法 Download PDF

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JP7017509B2
JP7017509B2 JP2018526088A JP2018526088A JP7017509B2 JP 7017509 B2 JP7017509 B2 JP 7017509B2 JP 2018526088 A JP2018526088 A JP 2018526088A JP 2018526088 A JP2018526088 A JP 2018526088A JP 7017509 B2 JP7017509 B2 JP 7017509B2
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cancer
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pharmaceutical combination
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JP2018534321A5 (OSRAM
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ジョン ソーン，
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センワ バイオサイエンシズ インコーポレイテッド
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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JP2018526088A 2015-11-20 2016-11-09 がんを治療するための四環式キノロン類似体の併用療法 Active JP7017509B2 (ja)

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JP2021197736A JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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US201562258211P 2015-11-20 2015-11-20
US62/258,211 2015-11-20
PCT/US2016/061176 WO2017087235A1 (en) 2015-11-20 2016-11-09 Combination therapy of tetracyclic quinolone analogs for treating cancer

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JP2021197736A Division JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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JP2018534321A JP2018534321A (ja) 2018-11-22
JP2018534321A5 JP2018534321A5 (OSRAM) 2020-02-13
JP7017509B2 true JP7017509B2 (ja) 2022-02-08

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JP2018526088A Active JP7017509B2 (ja) 2015-11-20 2016-11-09 がんを治療するための四環式キノロン類似体の併用療法
JP2021197736A Withdrawn JP2022020003A (ja) 2015-11-20 2021-12-06 がんを治療するための四環式キノロン類似体の併用療法

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US (4) US10857156B2 (OSRAM)
EP (1) EP3377068B1 (OSRAM)
JP (2) JP7017509B2 (OSRAM)
KR (2) KR20250065935A (OSRAM)
CN (2) CN119185322A (OSRAM)
AU (3) AU2016355268B2 (OSRAM)
CA (1) CA3005730A1 (OSRAM)
IL (1) IL259423A (OSRAM)
RU (1) RU2752506C2 (OSRAM)
TW (1) TWI730013B (OSRAM)
WO (1) WO2017087235A1 (OSRAM)

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TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
AU2017330390A1 (en) * 2016-09-23 2019-04-18 The Johns Hopkins University Combinatory treatment strategies of cancer based on RNA polymerase I inhibition
EP3601286A4 (en) 2017-03-28 2020-09-23 Pimera, Inc. NEW CRYSTALLINE FORMS OF A POL1 INHIBITOR
US11130740B2 (en) 2017-04-25 2021-09-28 Arbutus Biopharma Corporation Substituted 2,3-dihydro-1H-indene analogs and methods using same
US20210030735A1 (en) * 2018-02-05 2021-02-04 Tesaro, Inc. Pediatric niraparib formulations and pediatric treatment methods
KR20200131251A (ko) * 2018-02-15 2020-11-23 센화 바이오사이언시즈 인코포레이티드 퀴놀론 유사체 및 이의 염, 조성물, 및 이들의 사용 방법
WO2019177011A1 (ja) * 2018-03-13 2019-09-19 国立大学法人大阪大学 腫瘍免疫賦活剤
US12083118B2 (en) 2018-03-29 2024-09-10 Arbutus Biopharma Corporation Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same
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US20230158071A1 (en) * 2018-12-07 2023-05-25 Crage Medical Co., Limited Tumor combined immunotherapy
CN113453685A (zh) 2019-02-18 2021-09-28 美迪维尔公司 使用口服给药的二氧戊环核苷酸与抗pd1或抗pdl1单克隆抗体的组合治疗肝癌的方法
CN110075061A (zh) * 2019-03-13 2019-08-02 安庆瑄宇医药科技有限公司 一种尼拉帕尼口服液及其制备方法
CN114599368A (zh) * 2019-08-14 2022-06-07 生华生物科技股份有限公司 四环化合物及其盐、组合物以及其使用方法
IL294399A (en) * 2020-01-09 2022-08-01 Astrazeneca Ab Combination therapy for treating cancer
CN113491768A (zh) * 2020-04-01 2021-10-12 深圳市罗湖区人民医院 Cd137抗体在制备促进nk细胞表达cd16分子的药物中的应用
WO2022036067A1 (en) * 2020-08-12 2022-02-17 Servier Pharmaceuticals, Llc Combination therapies for use in treating cancer
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用
CN115160341B (zh) * 2022-07-18 2023-07-18 中国医学科学院医学实验动物研究所 苯并噁嗪类化合物及其药物用途
CN119768184A (zh) * 2022-08-30 2025-04-04 东丽株式会社 用于癌的治疗和/或预防的药品
CN116063328B (zh) * 2023-03-29 2023-06-20 信义核新(北京)生物科技有限公司 一种四环喹诺酮化合物、药学上可接受的盐及其应用
WO2024222630A1 (zh) * 2023-04-23 2024-10-31 信义核新(北京)生物科技有限公司 喹诺酮衍生物及其在抗肿瘤中的应用
WO2024242545A1 (ko) * 2023-05-23 2024-11-28 (주) 메티메디제약 칼슘 락테이트를 활성 성분으로 포함하는 암 백신 조성물 및 그 용도
WO2025101688A1 (en) * 2023-11-08 2025-05-15 Mary Hitchcock Memorial Hospital For Itself And On Behalf Of Dartmouth-Hitchcock Clinic (Collectively Doing Business As Dartmouth-Hitchcock) Combination therapy using tetrathiomolybdate

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