JP6980370B2 - 顕微鏡システム - Google Patents

顕微鏡システム Download PDF

Info

Publication number
JP6980370B2
JP6980370B2 JP2016167334A JP2016167334A JP6980370B2 JP 6980370 B2 JP6980370 B2 JP 6980370B2 JP 2016167334 A JP2016167334 A JP 2016167334A JP 2016167334 A JP2016167334 A JP 2016167334A JP 6980370 B2 JP6980370 B2 JP 6980370B2
Authority
JP
Japan
Prior art keywords
optical axis
objective
mirror
objective optical
objective lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016167334A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018036337A5 (enExample
JP2018036337A (ja
Inventor
竜男 中田
厚志 土井
兼太郎 井元
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to JP2016167334A priority Critical patent/JP6980370B2/ja
Priority to US15/683,980 priority patent/US10281699B2/en
Publication of JP2018036337A publication Critical patent/JP2018036337A/ja
Publication of JP2018036337A5 publication Critical patent/JP2018036337A5/ja
Application granted granted Critical
Publication of JP6980370B2 publication Critical patent/JP6980370B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0044—Scanning details, e.g. scanning stages moving apertures, e.g. Nipkow disks, rotating lens arrays
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0048—Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
JP2016167334A 2016-08-29 2016-08-29 顕微鏡システム Active JP6980370B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2016167334A JP6980370B2 (ja) 2016-08-29 2016-08-29 顕微鏡システム
US15/683,980 US10281699B2 (en) 2016-08-29 2017-08-23 Microscope system configured to irradiate focused light onto an area of a specimen outside of an optical axis of an objective lens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2016167334A JP6980370B2 (ja) 2016-08-29 2016-08-29 顕微鏡システム

Publications (3)

Publication Number Publication Date
JP2018036337A JP2018036337A (ja) 2018-03-08
JP2018036337A5 JP2018036337A5 (enExample) 2019-11-07
JP6980370B2 true JP6980370B2 (ja) 2021-12-15

Family

ID=61242347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016167334A Active JP6980370B2 (ja) 2016-08-29 2016-08-29 顕微鏡システム

Country Status (2)

Country Link
US (1) US10281699B2 (enExample)
JP (1) JP6980370B2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110653488A (zh) * 2019-10-16 2020-01-07 东南大学 一种跨尺度高分辨三维激光直写加工方法
CN120239815A (zh) * 2023-06-13 2025-07-01 深圳华大生命科学研究院 生物芯片的扫描成像系统

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623613A1 (de) * 1986-07-12 1988-01-21 Zeiss Carl Fa Koaxiales beleuchtungssystem fuer operationsmikroskope
JP3584301B2 (ja) * 1996-03-12 2004-11-04 株式会社ニコン 顕微鏡用架台
JP3917731B2 (ja) 1996-11-21 2007-05-23 オリンパス株式会社 レーザ走査顕微鏡
US20030002148A1 (en) 1998-10-24 2003-01-02 Johann Engelhardt Arrangement for optically scanning an object
JP2003524194A (ja) 1998-10-24 2003-08-12 ライカ ミクロジュステムス ハイデルベルク ゲーエムベーハー 対象物を光学的に走査するための装置
US7170676B2 (en) * 2003-03-13 2007-01-30 Olympus Corporation Illumination switching apparatus and method
GB0608258D0 (en) * 2006-04-26 2006-06-07 Perkinelmer Singapore Pte Ltd Spectroscopy using attenuated total internal reflectance (ATR)
US8040597B2 (en) * 2006-05-16 2011-10-18 Olympus Corporation Illuminating device
JP2008225095A (ja) * 2007-03-13 2008-09-25 Olympus Corp 光走査型観察装置
JP2009058776A (ja) * 2007-08-31 2009-03-19 Olympus Corp フォーカシング光学系を有する光学系およびこれを用いたレーザ顕微鏡装置
DE102009028149B4 (de) * 2009-07-31 2011-12-08 Leica Instruments (Singapore) Pte. Ltd. Beleuchtungseinrichtung für ein Mikroskop
JP2011118069A (ja) * 2009-12-02 2011-06-16 Nikon Corp 顕微鏡用照明装置および顕微鏡
DE102012211943A1 (de) * 2012-07-09 2014-06-12 Carl Zeiss Microscopy Gmbh Mikroskop
US9036146B2 (en) * 2013-01-21 2015-05-19 Sciaps, Inc. Micro purge of plasma region
US20140333998A1 (en) * 2013-03-12 2014-11-13 Board Of Trustees, Southern Illinois University Micro-lens for high resolution microscopy
US10718931B2 (en) * 2014-12-23 2020-07-21 Apple Inc. Confocal inspection system having averaged illumination and averaged collection paths
JP6634263B2 (ja) 2015-10-16 2020-01-22 オリンパス株式会社 顕微鏡

Also Published As

Publication number Publication date
US20180059397A1 (en) 2018-03-01
US10281699B2 (en) 2019-05-07
JP2018036337A (ja) 2018-03-08

Similar Documents

Publication Publication Date Title
EP2317363B1 (en) Microscope connecting unit and microscope system
US7639357B2 (en) Laser scanning microscope
US7369308B2 (en) Total internal reflection fluorescence microscope
EP1580586B1 (en) Scanning confocal microscope
EP2322969B1 (en) Microscope device
WO2012035903A1 (ja) ３次元共焦点観察用装置及び観察焦点面変位・補正ユニット
JP2018527607A (ja) ３次元イメージングのためのシステムおよび方法
US6924490B2 (en) Microscope system
JP3861357B2 (ja) 光学装置と一体化された顕微鏡用レボルバおよび顕微鏡
JP5991850B2 (ja) 顕微鏡装置
JP6980370B2 (ja) 顕微鏡システム
JP2016109858A (ja) 観察装置
JP6192397B2 (ja) レーザ顕微鏡
JP4889375B2 (ja) 共焦点顕微鏡および多光子励起型顕微鏡
JP7094225B2 (ja) 試料を検査する方法および顕微鏡
JP6385711B2 (ja) 顕微鏡装置
JPH0821956A (ja) 走査型光学顕微鏡
JP4694760B2 (ja) 顕微鏡
JP2008275791A (ja) 走査型共焦点顕微鏡
JP2006106346A (ja) 顕微鏡システム
JP4242627B2 (ja) レーザ顕微鏡
JP2014056078A (ja) 画像取得装置、画像取得システム及び顕微鏡装置
JP2009116317A (ja) 顕微鏡装置
JP6436862B2 (ja) 顕微鏡および顕微鏡画像取得方法
JP2009163201A (ja) 立体顕微鏡

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20190829

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190924

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20200826

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20200915

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20201111

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210126

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210317

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210608

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210708

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20211102

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20211117

R151 Written notification of patent or utility model registration

Ref document number: 6980370

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R151

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250