JP6735742B2 - ドライアイの治療のための刺激装置及び方法 - Google Patents

ドライアイの治療のための刺激装置及び方法 Download PDF

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Publication number
JP6735742B2
JP6735742B2 JP2017522151A JP2017522151A JP6735742B2 JP 6735742 B2 JP6735742 B2 JP 6735742B2 JP 2017522151 A JP2017522151 A JP 2017522151A JP 2017522151 A JP2017522151 A JP 2017522151A JP 6735742 B2 JP6735742 B2 JP 6735742B2
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Prior art keywords
electrode
stimulator
patient
nasal
waveform
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Expired - Fee Related
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JP2017522151A
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Japanese (ja)
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JP2017531529A (ja
JP2017531529A5 (enExample
Inventor
マンフレート フランケ
マンフレート フランケ
ジェームズ ドナルド ラウディン
ジェームズ ドナルド ラウディン
ジョン ワードル
ジョン ワードル
マーク ジェフリー ホールドブルック
マーク ジェフリー ホールドブルック
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オキュリーブ， インコーポレイテッド
オキュリーブ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0546—Nasal electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37205—Microstimulators, e.g. implantable through a cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A61N1/37247—User interfaces, e.g. input or presentation means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3756—Casings with electrodes thereon, e.g. leadless stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/3758—Packaging of the components within the casing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Human Computer Interaction (AREA)
  • Rehabilitation Therapy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Electrotherapy Devices (AREA)
JP2017522151A 2014-10-22 2015-10-22 ドライアイの治療のための刺激装置及び方法 Expired - Fee Related JP6735742B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462067416P 2014-10-22 2014-10-22
US62/067,416 2014-10-22
PCT/US2015/057023 WO2016065215A1 (en) 2014-10-22 2015-10-22 Stimulation devices and methods for treating dry eye

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020120696A Division JP2020189105A (ja) 2014-10-22 2020-07-14 ドライアイの治療のための刺激装置及び方法

Publications (3)

Publication Number Publication Date
JP2017531529A JP2017531529A (ja) 2017-10-26
JP2017531529A5 JP2017531529A5 (enExample) 2019-03-28
JP6735742B2 true JP6735742B2 (ja) 2020-08-05

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JP2017522151A Expired - Fee Related JP6735742B2 (ja) 2014-10-22 2015-10-22 ドライアイの治療のための刺激装置及び方法
JP2020120696A Pending JP2020189105A (ja) 2014-10-22 2020-07-14 ドライアイの治療のための刺激装置及び方法

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Country Status (13)

Country Link
US (4) US9737712B2 (enExample)
EP (2) EP3721938A1 (enExample)
JP (2) JP6735742B2 (enExample)
KR (1) KR20170074926A (enExample)
CN (1) CN107106843A (enExample)
AU (2) AU2015335776B2 (enExample)
BR (1) BR112017008267A2 (enExample)
CA (1) CA2965186A1 (enExample)
ES (1) ES2809599T3 (enExample)
IL (1) IL251788B (enExample)
MX (1) MX2017005204A (enExample)
RU (1) RU2707167C2 (enExample)
WO (1) WO2016065215A1 (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
EP2967817B1 (en) 2013-03-12 2021-03-10 Oculeve, Inc. Implant delivery devices and systems
JP6795975B2 (ja) 2013-04-19 2020-12-02 オキュリーブ， インコーポレイテッド 鼻刺激デバイス及び方法
WO2015048806A2 (en) 2013-09-30 2015-04-02 Nidus Medical, Llc Apparatus and methods for treating rhinitis
MX2016011118A (es) 2014-02-25 2016-12-05 Oculeve Inc Formulaciones de polimeros para estimulacion nasolagrimal.
US9763743B2 (en) 2014-07-25 2017-09-19 Arrinex, Inc. Apparatus and method for treating rhinitis
EP3171928B1 (en) 2014-07-25 2020-02-26 Oculeve, Inc. Stimulation patterns for treating dry eye
EP3209370A4 (en) 2014-10-22 2018-05-30 Oculeve, Inc. Contact lens for increasing tear production
CA2965363A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Implantable nasal stimulator systems and methods
US9737712B2 (en) 2014-10-22 2017-08-22 Oculeve, Inc. Stimulation devices and methods for treating dry eye
US20180001107A1 (en) 2016-07-01 2018-01-04 Btl Holdings Limited Aesthetic method of biological structure treatment by magnetic field
ITUB20154761A1 (it) * 2015-10-29 2017-04-29 Resono Ophthalmic S R L Sistema di elettrodo e relativo dispositivo per il trattamento di patologie dell?occhio, in particolare dell?occhio secco
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
US10695219B2 (en) * 2016-04-08 2020-06-30 ThermiGen, LLC Apparatus and method for treatment of dry eye using radio frequency heating
US10918864B2 (en) 2016-05-02 2021-02-16 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US11534619B2 (en) 2016-05-10 2022-12-27 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
RU169012U1 (ru) * 2016-08-08 2017-03-01 Дмитрий Викторович Давыдов Электрод для электростимуляции зрительного нерва и зрительных путей и контроля физиологических параметров орбитальных структур глаза
US11141219B1 (en) 2016-08-16 2021-10-12 BTL Healthcare Technologies, a.s. Self-operating belt
CN114367066B (zh) 2016-10-14 2023-05-23 欧灵比克眼科公司 用于眼部病症的治疗性超声
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
WO2018102535A1 (en) 2016-12-02 2018-06-07 Oculeve, Inc. Apparatus and method for dry eye forecast and treatment recommendation
JP6854513B2 (ja) * 2017-04-05 2021-04-07 国立大学法人 鹿児島大学 分泌促進装置
CN110573210A (zh) * 2017-04-28 2019-12-13 提维克健康系统股份有限公司 用于微电流刺激设备的自适应触发器
CA3067212A1 (en) 2017-06-16 2018-12-20 AesculaTech, Inc. Thermoresponsive polymers and uses thereof
US20200046980A1 (en) * 2017-08-11 2020-02-13 Boston Scientific Neuromodulation Corporation Varying Stimulation Parameters to Prevent Tissue Habituation in a Spinal Cord Stimulation System
CN109960182B (zh) * 2017-12-22 2024-07-09 深圳市上示科技有限公司 一种信号发生装置以及具有信号发生装置的设备
WO2019138407A1 (en) * 2018-01-11 2019-07-18 Theranica Bio-Electronics Ltd. Electrode patch
US11141348B2 (en) 2018-02-26 2021-10-12 Olympic Ophthalmics, Inc. Treatment methods using handheld devices for disorders
US11338139B2 (en) 2018-10-01 2022-05-24 Biovisics Medical, Inc. System and methods for controlled electrical modulation for vision therapy
WO2020112980A2 (en) 2018-11-30 2020-06-04 Biovisics Medical, Llc Head worn apparatuses for vision therapy
DE102019214752B4 (de) 2019-09-26 2022-12-15 CereGate GmbH Neuronales signalsystem, verfahren und computerprogramm zumsignalisieren eines gerätezustands
DE102019202666B4 (de) 2019-02-27 2021-04-29 CereGate GmbH Neuronales Kommunikationssystem
DE102019209096B4 (de) 2019-06-24 2022-12-15 CereGate GmbH Neuronales signalsystem zur verhaltensmodifikation
US11376432B2 (en) * 2019-03-26 2022-07-05 Twenty Twenty Therapeutics Llc Non-invasive periocular device for dry-eye treatment
EP3952979A1 (en) 2019-04-10 2022-02-16 Biovisics Medical, Inc. Systems and interfaces for ocular therapy
US12156689B2 (en) 2019-04-11 2024-12-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
JP7125033B2 (ja) 2019-04-11 2022-08-24 ビーティーエル メディカル ソリューションズ エー．エス． 無線周波数及び磁気エネルギーによる生物学的構造の美的処置の方法及びデバイス
EP4464367A3 (en) 2019-06-14 2025-01-22 i-LUMEN Scientific, Inc. Wearable medical device
US11065461B2 (en) 2019-07-08 2021-07-20 Bioness Inc. Implantable power adapter
WO2021011255A1 (en) * 2019-07-12 2021-01-21 Biovisics Medical, Inc. Ocular therapy modes and systems
WO2021113486A1 (en) * 2019-12-03 2021-06-10 Biovisics Medical, Inc. Systems, implantable devices and methods for vision related stimulation
FR3105005A1 (fr) * 2019-12-18 2021-06-25 L'oreal Dispositif et procédé de stimulation de cellules de peau à l’aide d’un microcourant
EP4146335B1 (en) 2020-05-04 2024-11-13 BTL Healthcare Technologies a.s. Device for unattended treatment of a patient
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
AU2021272920A1 (en) * 2020-05-15 2022-12-15 I-Lumen Scientific, Inc. Electrode system for vision treatment and method
DE102020210676B4 (de) 2020-08-21 2024-08-01 CereGate GmbH Closed-loop computer-gehirn-schnittstellenvorrichtung
US12357817B2 (en) 2021-04-06 2025-07-15 Aerin Medical Inc. Nasal neuromodulation devices and methods
US12409325B2 (en) 2021-04-07 2025-09-09 CereGate GmbH Closed-loop autocalibration method for a computer brain interface device, computer program and computer brain interface device
US12214202B2 (en) 2021-04-07 2025-02-04 CereGate GmbH On-line autocalibration method for a computer brain interface device and computer brain interface device
CA3260012A1 (en) 2021-10-13 2023-04-20 Btl Medical Solutions A S AESTHETIC TREATMENT DEVICES FOR BIOLOGICAL STRUCTURES USING RADIOFREQUENCY AND MAGNETIC ENERGY
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
CN119158181B (zh) * 2024-11-14 2025-05-02 复远数科医疗(杭州)有限公司 一种治疗眼部疾病的穿戴式装置

Family Cites Families (444)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2525381A (en) 1947-09-25 1950-10-10 Tower Paul Contact-type electrode holder
US2512882A (en) 1949-08-17 1950-06-27 R G Truesdale Co Inc Serum inoculator
US3620219A (en) 1969-05-07 1971-11-16 Donald E Barker Facial nerve stimulator
US3709228A (en) 1971-01-07 1973-01-09 D Barker Apparatus for facial stimulation
FR2210298A5 (enExample) 1972-12-08 1974-07-05 Commissariat Energie Atomique
USD257495S (en) 1979-05-29 1980-11-04 Hot Shot Products Co. Housing for an electric cattle prod
US4684362A (en) 1981-03-12 1987-08-04 Holt James J Method for collecting nasal secretions
US4520825A (en) 1982-04-30 1985-06-04 Medtronic, Inc. Digital circuit for control of gradual turn-on of electrical tissue stimulators
US4495676A (en) 1982-08-02 1985-01-29 Hartmetz Ii Gerald J Apparatus for electrically stimulating an animal carcass
CH677883A5 (enExample) 1982-11-15 1991-07-15 Symtonic Sa
US4539988A (en) 1983-07-05 1985-09-10 Packaging Corporation International Disposable automatic lancet
US5025807A (en) 1983-09-14 1991-06-25 Jacob Zabara Neurocybernetic prosthesis
US4590942A (en) 1984-02-17 1986-05-27 Biosonics, Inc. Apparatus and method for inhibiting nasal secretions
DE3501095A1 (de) 1985-01-15 1986-07-17 Gerd Prof. Dr. 8520 Erlangen Kobal Verfahren zur messung von sensorischen qualitaeten und einrichtung zur durchfuehrung des verfahrens
JPS61203935A (ja) 1985-03-07 1986-09-09 日石三菱株式会社 網膜電図測定用電極
US4628933A (en) 1985-07-23 1986-12-16 Michelson Robin P Method and apparatus for visual prosthesis
NZ214348A (en) 1985-11-27 1988-07-28 Walker T H & Sons Ltd Electrically stunning animals through nose and neck contacts
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4777954A (en) 1986-06-30 1988-10-18 Nepera Inc. Conductive adhesive medical electrode assemblies
US4706680A (en) 1986-06-30 1987-11-17 Nepera Inc. Conductive adhesive medical electrode assemblies
US4957480A (en) 1988-02-02 1990-09-18 Universal Health Products, Inc. Method of facial toning
US4926880A (en) 1988-11-08 1990-05-22 Microcurrents Method for relieving sinus and nasal congestion utilizing microcurrents
US4988358A (en) 1988-12-28 1991-01-29 Eppley Barry L Method for promoting hard tissue growth and repair in mammals
US5259373A (en) 1989-05-19 1993-11-09 Puritan-Bennett Corporation Inspiratory airway pressure system controlled by the detection and analysis of patient airway sounds
RU1799577C (ru) 1989-08-17 1993-03-07 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ улучшени зрительных функций при заболевани х зрительного нерва и сетчатки и устройство дл его осуществлени
US5078733A (en) 1990-04-12 1992-01-07 Eveleigh Robert B Pacifier for premature newborns
US5090422A (en) 1990-04-19 1992-02-25 Cardiac Pacemakers, Inc. Implantable electrode pouch
US5099829A (en) 1990-04-25 1992-03-31 Wu An Chuan Massage device good for eyes
US5342410A (en) 1990-10-05 1994-08-30 Eric Braverman Apparatus and method for increasing the amplitude of P300 waves in the human brain
US5072724A (en) 1990-11-23 1991-12-17 Joseph Marcus Vibrational liquid-wave stimulating therapy mask apparatus for facial health and beauty care
US5533470A (en) 1991-07-05 1996-07-09 Rose; Andrew F. Electronic nose-clip with solar cell
US5640978A (en) 1991-11-06 1997-06-24 Diolase Corporation Method for pain relief using low power laser light
US5193539A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Implantable microstimulator
US6063079A (en) * 1995-06-07 2000-05-16 Arthrocare Corporation Methods for electrosurgical treatment of turbinates
US5352445A (en) 1992-05-07 1994-10-04 Lavaux Joseph E Lavaux tear test lacrimal equilibration time (LET)
US5514131A (en) 1992-08-12 1996-05-07 Stuart D. Edwards Method for the ablation treatment of the uvula
US5360438A (en) 1993-01-26 1994-11-01 Fisher Mary R Method and device for improving cranial nerve function to improve muscle function and thereby overcome visual/perceptual dysfunction
JP3517242B2 (ja) 1993-01-28 2004-04-12 ノバルティス アクチエンゲゼルシャフト ポリマー物品の製造に用いる材料
US5345948A (en) 1993-04-08 1994-09-13 Donnell Jr Francis E O Method of performing translactrimal laser dacryocystorhinostomy
US5545617A (en) 1993-11-12 1996-08-13 The Schepens Eye Research Institute, Inc. Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion
US5713833A (en) 1994-01-26 1998-02-03 Milligan; Lee John Septum nerve stimulator
ES2123237T3 (es) 1994-01-31 1999-01-01 Bausch & Lomb Metodo de moldear por vaciado lentes de contacto toricas.
IL108772A0 (en) 1994-02-24 1994-05-30 Amcor Ltd Treatment of rhinitis by biostimulative illumination
AUPM982694A0 (en) * 1994-12-02 1995-01-05 University Of Queensland, The Iontophoresis method and apparatus
US5643336A (en) 1995-01-09 1997-07-01 Lopez-Claros; Marcelo Enrique Heating and cooling pad
US5735817A (en) 1995-05-19 1998-04-07 Shantha; T. R. Apparatus for transsphenoidal stimulation of the pituitary gland and adjoining brain structures
US5640764A (en) 1995-05-22 1997-06-24 Alfred E. Mann Foundation For Scientific Research Method of forming a tubular feed-through hermetic seal for an implantable medical device
US5571101A (en) 1995-05-25 1996-11-05 Ellman; Alan G. Electrosurgical electrode for DCR surgical procedure
US5707400A (en) 1995-09-19 1998-01-13 Cyberonics, Inc. Treating refractory hypertension by nerve stimulation
US5607461A (en) * 1995-10-20 1997-03-04 Nexmed, Inc. Apparatus and method for delivering electrical stimulus to tissue
DE19549297C2 (de) 1995-12-22 1998-07-02 Guenter Stielau Verfahren und Vorrichtung zur Beeinflussung der menschlichen Psyche
US6051017A (en) 1996-02-20 2000-04-18 Advanced Bionics Corporation Implantable microstimulator and systems employing the same
US5900407A (en) 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
US6549800B1 (en) 1996-04-25 2003-04-15 Johns Hopkins Unversity School Of Medicine Methods for in vivo magnetic resonance imaging
BR9711214A (pt) 1996-08-23 2000-01-11 Osteobiologics Inc Dispositivo e processo para medir uma propriedade de compressão de um material, e, processos para determinar a saúde ou doença de cartilagem e para fabricar o dispositivo.
US5697957A (en) 1996-08-29 1997-12-16 Pacesetter Ab Adaptive method and apparatus for extracting an evoked response component from a sensed cardiac signal by suppressing electrode polarization components
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US5800685A (en) 1996-10-28 1998-09-01 Cardiotronics Systems, Inc. Electrically conductive adhesive hydrogels
US7460911B2 (en) 1997-02-26 2008-12-02 Alfred E. Mann Foundation For Scientific Research System and method suitable for treatment of a patient with a neurological deficit by sequentially stimulating neural pathways using a system of discrete implantable medical devices
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US6458157B1 (en) 1997-08-04 2002-10-01 Suaning Gregg Joergen Retinal stimulator
US6020445A (en) 1997-10-09 2000-02-01 Johnson & Johnson Vision Products, Inc. Silicone hydrogel polymers
AU1205799A (en) 1997-10-29 1999-05-17 J-Med Pharmaceuticals, Inc. Antihistamine/decongestant regimens for treating rhinitis
US6083251A (en) 1997-11-13 2000-07-04 Shindo; Kohei Eye treatment method and apparatus
FR2771297B1 (fr) * 1997-11-25 2000-02-11 Pierre Andre Jacques Bige Sonde bicanaliculaire pour le traitement du larmoiement de l'oeil
US6050999A (en) 1997-12-18 2000-04-18 Keravision, Inc. Corneal implant introducer and method of use
US5935155A (en) 1998-03-13 1999-08-10 John Hopkins University, School Of Medicine Visual prosthesis and method of using same
US6324429B1 (en) 1998-05-08 2001-11-27 Massachusetts Eye And Ear Infirmary Chronically implantable retinal prosthesis
EP1100402A4 (en) 1998-07-06 2008-12-10 Boston Scient Neuromodulation IMPLANTABLE STIMULATION SYSTEM AND METHOD FOR TREATMENT OF URINARY INCONTINENCE
US6035236A (en) 1998-07-13 2000-03-07 Bionergy Therapeutics, Inc. Methods and apparatus for electrical microcurrent stimulation therapy
US6272382B1 (en) 1998-07-31 2001-08-07 Advanced Bionics Corporation Fully implantable cochlear implant system
US6240316B1 (en) 1998-08-14 2001-05-29 Advanced Bionics Corporation Implantable microstimulation system for treatment of sleep apnea
IL141755A0 (en) 1998-09-04 2002-03-10 Wolfe Res Pty Ltd Medical implant system
US7346389B1 (en) 1998-09-24 2008-03-18 Newsome David A Dilation enhancer with pre-medicated contact lenses
US5948006A (en) 1998-10-14 1999-09-07 Advanced Bionics Corporation Transcutaneous transmission patch
US6275737B1 (en) 1998-10-14 2001-08-14 Advanced Bionics Corporation Transcutaneous transmission pouch
US6208902B1 (en) 1998-10-26 2001-03-27 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy for pain syndromes utilizing an implantable lead and an external stimulator
US7076307B2 (en) 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US6205359B1 (en) 1998-10-26 2001-03-20 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6366814B1 (en) 1998-10-26 2002-04-02 Birinder R. Boveja External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders
US6564102B1 (en) 1998-10-26 2003-05-13 Birinder R. Boveja Apparatus and method for adjunct (add-on) treatment of coma and traumatic brain injury with neuromodulation using an external stimulator
US6329485B1 (en) 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants
GB2345010B (en) 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
AU772100B2 (en) 1999-02-08 2004-04-08 Cochlear Limited Offset coils for radio frequency transcutaneous links
US8636648B2 (en) 1999-03-01 2014-01-28 West View Research, Llc Endoscopic smart probe
WO2000052466A2 (en) 1999-03-05 2000-09-08 University Of Miami Measurement of tear fluorescein clearance
ATE430596T1 (de) 1999-03-24 2009-05-15 Second Sight Medical Prod Inc Retinale farbprothese zur wiederherstellung des farbsehens
US6178352B1 (en) 1999-05-07 2001-01-23 Woodside Biomedical, Inc. Method of blood pressure moderation
US6200626B1 (en) 1999-05-20 2001-03-13 Bausch & Lomb Incorporated Surface-treatment of silicone medical devices comprising an intermediate carbon coating and graft polymerization
TWI225398B (en) 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
US7177690B2 (en) 1999-07-27 2007-02-13 Advanced Bionics Corporation Implantable system having rechargeable battery indicator
US6516227B1 (en) 1999-07-27 2003-02-04 Advanced Bionics Corporation Rechargeable spinal cord stimulator system
US6237604B1 (en) 1999-09-07 2001-05-29 Scimed Life Systems, Inc. Systems and methods for preventing automatic identification of re-used single use devices
US6368324B1 (en) 1999-09-24 2002-04-09 Medtronic Xomed, Inc. Powered surgical handpiece assemblies and handpiece adapter assemblies
US6853946B2 (en) 1999-11-05 2005-02-08 Adam Cohen Air flow sensing and control for animal confinement system
EP1110509A1 (en) 1999-12-21 2001-06-27 Tomaso Vercellotti Surgical device for bone surgery
US6885888B2 (en) 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
US20040039401A1 (en) 2000-03-31 2004-02-26 Chow Alan Y. Implant instrument
US6277855B1 (en) 2000-04-21 2001-08-21 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with nicotinic acetylcholine receptor agonists
US6284765B1 (en) 2000-04-27 2001-09-04 The University Of North Texas Health Science Center At Fort Worth (+) naloxone and epinephrine combination therapy
US6853858B2 (en) 2000-05-08 2005-02-08 Brainsgate, Ltd. Administration of anti-inflammatory drugs into the central nervous system
US7117033B2 (en) 2000-05-08 2006-10-03 Brainsgate, Ltd. Stimulation for acute conditions
CN1440256A (zh) 2000-05-08 2003-09-03 布雷恩斯盖特有限公司 通过刺激蝶腭神经节改善bbb和脑部血流性质的方法及装置
US7146209B2 (en) 2000-05-08 2006-12-05 Brainsgate, Ltd. Stimulation for treating eye pathologies
US20020035358A1 (en) 2000-05-09 2002-03-21 Ming Wang Pulsed electromagnetic field therapy for treatment of corneal disorders and injuries
US6327504B1 (en) 2000-05-10 2001-12-04 Thoratec Corporation Transcutaneous energy transfer with circuitry arranged to avoid overheating
US6592860B1 (en) 2000-05-30 2003-07-15 Soluble Systems, Llc Composition and applicator for topical substance delivery
US6526318B1 (en) 2000-06-16 2003-02-25 Mehdi M. Ansarinia Stimulation method for the sphenopalatine ganglia, sphenopalatine nerve, or vidian nerve for treatment of medical conditions
DE60140025D1 (de) 2000-06-19 2009-11-12 Medtronic Inc Implantierbares medizinisches Gerät mit einer externen Nachladespule
US6505077B1 (en) 2000-06-19 2003-01-07 Medtronic, Inc. Implantable medical device with external recharging coil electrical connection
US6871099B1 (en) 2000-08-18 2005-03-22 Advanced Bionics Corporation Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain
US6539253B2 (en) 2000-08-26 2003-03-25 Medtronic, Inc. Implantable medical device incorporating integrated circuit notch filters
US6535766B1 (en) 2000-08-26 2003-03-18 Medtronic, Inc. Implanted medical device telemetry using integrated microelectromechanical filtering
DE60143621D1 (de) 2000-09-13 2011-01-20 Gerät zur konditionierung von muskeln im schlaf
WO2002032499A1 (en) 2000-09-14 2002-04-25 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Method and apparatus to treat disorders of gastrointestinal peristalsis
US6405079B1 (en) 2000-09-22 2002-06-11 Mehdi M. Ansarinia Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions
US6652095B2 (en) 2000-11-17 2003-11-25 Hsiao-Ching Tung Orthokeratology and bi-focal contact lens
US20050251061A1 (en) 2000-11-20 2005-11-10 Schuler Eleanor L Method and system to record, store and transmit waveform signals to regulate body organ function
JP2002159340A (ja) 2000-11-28 2002-06-04 Ya Man Ltd 美顔装置
WO2002060522A2 (en) 2001-01-30 2002-08-08 Saliwizer Itd. System and method for electrical stimulation of salivation
EP1234553A1 (de) 2001-02-14 2002-08-28 Boris-Wolfgang Hochleitner Bioartifizielles Gerät
JP4781576B2 (ja) 2001-02-28 2011-09-28 株式会社ニデック 眼内埋め込み型視覚刺激装置
NO313683B1 (no) 2001-03-21 2002-11-18 Turid Bergersen Anordning for akupressurisk behandling
US6701189B2 (en) 2001-03-30 2004-03-02 Neurocontrol Corporation Systems and methods for performing prosthetic or therapeutic neuromuscular stimulation using a universal external controller accommodating different control inputs and/or different control outputs
JP2004526510A (ja) 2001-03-30 2004-09-02 ケース ウエスタン リザーブ ユニバーシティ 選択的生理学的応答を達成するための、陰部神経または陰部神経枝の中、その上またはその付近の成分を選択的に刺激するためのシステムおよび方法
US6662052B1 (en) 2001-04-19 2003-12-09 Nac Technologies Inc. Method and system for neuromodulation therapy using external stimulator with wireless communication capabilites
US7369897B2 (en) 2001-04-19 2008-05-06 Neuro And Cardiac Technologies, Llc Method and system of remotely controlling electrical pulses provided to nerve tissue(s) by an implanted stimulator system for neuromodulation therapies
WO2002086105A1 (en) 2001-04-20 2002-10-31 Chiron Corporation Delivery of polynucleotide agents to the central nervous sysstem
US6907295B2 (en) 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
AT411150B (de) 2001-05-25 2003-10-27 Nova Technical Res Gmbh Einrichtung zum einbringen von stoffen
US6537265B2 (en) 2001-06-08 2003-03-25 Health Research, Inc. Method for nasal application of a medicinal substance
US6792314B2 (en) 2001-06-18 2004-09-14 Alfred E. Mann Foundation For Scientific Research Miniature implantable array and stimulation system suitable for eyelid stimulation
US7054692B1 (en) 2001-06-22 2006-05-30 Advanced Bionics Corporation Fixation device for implantable microdevices
US20050004625A1 (en) 2001-06-29 2005-01-06 Chow Alan Y. Treatment of degenerative retinal disease via electrical stimulation of surface structures
US7031776B2 (en) 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US7778703B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US7885709B2 (en) 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7778711B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US7974693B2 (en) 2001-08-31 2011-07-05 Bio Control Medical (B.C.M.) Ltd. Techniques for applying, configuring, and coordinating nerve fiber stimulation
US6792312B2 (en) 2001-09-06 2004-09-14 Medtronic, Inc. Connector module having internal weld plates
US20030062050A1 (en) 2001-10-01 2003-04-03 Bruno Schmidt Anti-snoring devices and methods
US6829508B2 (en) 2001-10-19 2004-12-07 Alfred E. Mann Foundation For Scientific Research Electrically sensing and stimulating system for placement of a nerve stimulator or sensor
US6562036B1 (en) 2001-12-10 2003-05-13 Ellman Alan G Electrosurgical electrode for rhinoplasty
JP2003210513A (ja) 2002-01-23 2003-07-29 Nidek Co Ltd 眼科用治療装置
AU2003220574A1 (en) 2002-03-27 2003-10-13 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US6641799B2 (en) 2002-04-03 2003-11-04 Nos Spray, Inc. Nasal spray for decongesting nasal passages
US7645262B2 (en) 2002-04-11 2010-01-12 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
US7142909B2 (en) 2002-04-11 2006-11-28 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
US6974533B2 (en) 2002-04-11 2005-12-13 Second Sight Medical Products, Inc. Platinum electrode and method for manufacturing the same
US6604528B1 (en) 2002-04-22 2003-08-12 Lloyd P. Duncan Acid reflux and snoring device
US20060004423A1 (en) 2002-05-09 2006-01-05 Boveja Birinder R Methods and systems to provide therapy or alleviate symptoms of chronic headache, transformed migraine, and occipital neuralgia by providing rectangular and/or complex electrical pulses to occipital nerves
US8204591B2 (en) 2002-05-23 2012-06-19 Bio Control Medical (B.C.M.) Ltd. Techniques for prevention of atrial fibrillation
US8036745B2 (en) 2004-06-10 2011-10-11 Bio Control Medical (B.C.M.) Ltd. Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
EP1509281B1 (en) 2002-06-03 2013-08-07 Med-El Elektromedizinische Geräte GmbH Implantable device with flexible interconnect to coil
US7069084B2 (en) 2002-06-14 2006-06-27 Seefit Incorporated Method and apparatus for preventing and treating eyelid problems
US7860570B2 (en) 2002-06-20 2010-12-28 Boston Scientific Neuromodulation Corporation Implantable microstimulators and methods for unidirectional propagation of action potentials
US20040147973A1 (en) 2002-06-27 2004-07-29 Hauser Robert G. Intra cardiac pacer and method
US6904868B2 (en) 2002-07-12 2005-06-14 Robert S. Block Interactive mobile food dispenser
CN1301692C (zh) 2002-09-18 2007-02-28 阿勒根公司 眼植入物导入的器械
US7169163B2 (en) 2002-09-30 2007-01-30 Bruce Becker Transnasal method and catheter for lacrimal system
EP1551499A1 (en) 2002-10-04 2005-07-13 Microchips, Inc. Medical device for neural stimulation and controlled drug delivery
US7349741B2 (en) 2002-10-11 2008-03-25 Advanced Bionics, Llc Cochlear implant sound processor with permanently integrated replenishable power source
US20040092992A1 (en) 2002-10-23 2004-05-13 Kenneth Adams Disposable battery powered rotary tissue cutting instruments and methods therefor
JP2006515999A (ja) 2002-11-14 2006-06-15 ブレインズゲート リミティド 刺激のための外科用ツール及び技法
US7024241B1 (en) 2002-12-05 2006-04-04 Pacesetter, Inc. Pacing pulse waveforms that support simultaneous intracardiac signal sensing and analysis
TR200202651A2 (tr) 2002-12-12 2004-07-21 Met�N�Tulgar VücutÁdışındanÁdirekÁtedaviÁsinyaliÁtransferliÁÁbeyinÁpili
US7264859B2 (en) 2002-12-19 2007-09-04 Kimberly-Clark Worldwide, Inc. Lubricious coating for medical devices
US20050048099A1 (en) 2003-01-09 2005-03-03 Allergan, Inc. Ocular implant made by a double extrusion process
US7228184B2 (en) * 2003-02-22 2007-06-05 Chester Heath Viral-inhibiting method
US7321795B2 (en) 2003-03-24 2008-01-22 Les Bogdanowicz Compositions for electric stimulation of the eye
WO2004091453A1 (en) 2003-04-15 2004-10-28 Eyeborn (Proprietary) Limited An orbital implant applicator
US20060074450A1 (en) 2003-05-11 2006-04-06 Boveja Birinder R System for providing electrical pulses to nerve and/or muscle using an implanted stimulator
US7317947B2 (en) 2003-05-16 2008-01-08 Medtronic, Inc. Headset recharger for cranially implantable medical devices
EP1651307A2 (en) 2003-07-10 2006-05-03 Science Medicus, Inc. Regulation of endocrine and exocrine glands by means of neuro-electrical coded signals
US7725176B2 (en) 2003-07-10 2010-05-25 Schuler Eleanor L Method and system for regulation of endocrine and exocrine glands by means of neuro-electrical coded signals
JP2005052461A (ja) 2003-08-06 2005-03-03 Pop Denshi Kk 生体への電流印加装置
CN1253147C (zh) 2003-08-13 2006-04-26 复旦大学 一种超多孔水凝胶复合物,其制备方法及其在药剂学中的应用
ES2243116B1 (es) 2003-09-22 2007-02-01 Josep Duran Von Arx Estimulador nasal.
US7225032B2 (en) 2003-10-02 2007-05-29 Medtronic Inc. External power source, charger and system for an implantable medical device having thermal characteristics and method therefore
DE10353000A1 (de) 2003-11-13 2005-06-16 Physiomed Elektromedizin Ag Vorrichtung zur Elektrotherapie
AU2003296968A1 (en) 2003-12-12 2005-07-14 Richard W. Yee Method and apparatus for preventing and treating eyelid problems
US7045559B2 (en) 2003-12-18 2006-05-16 Kimberly-Clark Worldwide, Inc. Electrically conductive adhesive hydrogels with solubilizer
JP4879754B2 (ja) 2004-01-22 2012-02-22 リハブトロニクス インコーポレーテッド 移植された非活性導電体を介して、身体組織に電流を搬送する方法
US20080132969A1 (en) 2004-02-12 2008-06-05 Ndi Medical, Inc. Systems and methods for bilateral stimulation of left and right branches of the dorsal genital nerves to treat urologic dysfunctions
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US20050203600A1 (en) 2004-03-12 2005-09-15 Scimed Life Systems, Inc. Collapsible/expandable tubular electrode leads
CN2693275Y (zh) * 2004-03-30 2005-04-20 孙作东 作用于嗅觉神经的电子治疗仪
US7993381B2 (en) 2004-04-01 2011-08-09 Mac Beam, Inc. Method and apparatus for treating the body
US7571007B2 (en) 2004-04-12 2009-08-04 Advanced Neuromodulation Systems, Inc. Systems and methods for use in pulse generation
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US7359751B1 (en) 2004-05-05 2008-04-15 Advanced Neuromodulation Systems, Inc. Clinician programmer for use with trial stimulator
US7402175B2 (en) 2004-05-17 2008-07-22 Massachusetts Eye & Ear Infirmary Vision prosthesis orientation
US7330762B2 (en) 2004-06-07 2008-02-12 Neuro And Cardiac Technologies, Llc Method and system for providing pulsed electrical stimulation to provide therapy for erectile/sexual dysfunction, prostatitis, prostatitis pain, and chronic pelvic pain
US20050268472A1 (en) 2004-06-07 2005-12-08 Bourilkov Jordan T Shaving systems
WO2006007402A2 (en) 2004-06-16 2006-01-19 University Of Massachusets Poly (lactid acid) copolymer hydrogels and related methods of drug delivery
WO2006021957A2 (en) 2004-08-23 2006-03-02 Brainsgate Ltd. Concurrent bilateral spg modulation
US20090099623A1 (en) 2004-09-13 2009-04-16 Neuronix Ltd. Systems and methods for treatment of medical conditions related to the central nervous system and for enhancing cognitive functions
US7641688B2 (en) 2004-09-16 2010-01-05 Evera Medical, Inc. Tissue augmentation device
GB2418143B (en) 2004-09-21 2010-03-17 Can Do Corp Ltd Apparatus for behaviour modification
US7247692B2 (en) 2004-09-30 2007-07-24 Johnson & Johnson Vision Care, Inc. Biomedical devices containing amphiphilic block copolymers
EP1812104B1 (en) 2004-10-20 2012-11-21 Boston Scientific Limited Leadless cardiac stimulation systems
US7647109B2 (en) 2004-10-20 2010-01-12 Boston Scientific Scimed, Inc. Leadless cardiac stimulation systems
US7497836B2 (en) 2004-10-22 2009-03-03 General Patent Llc Germicidal method for treating or preventing sinusitis
CN101087822B (zh) 2004-10-28 2012-05-30 拜尔健康护理有限责任公司 水凝胶组合物
US8489189B2 (en) 2004-10-29 2013-07-16 Medtronic, Inc. Expandable fixation mechanism
US20060095077A1 (en) 2004-10-29 2006-05-04 Tronnes Carole A Expandable fixation structures
EP1652552B1 (en) 2004-11-02 2008-09-17 Sydney Biotech Pty. Ltd. Extraocular device
US20090264966A1 (en) 2004-11-02 2009-10-22 Pixeloptics, Inc. Device for Inductive Charging of Implanted Electronic Devices
US7547447B2 (en) 2004-11-15 2009-06-16 Doheny Eye Institute Bioartificial lacrimal gland
US20060107958A1 (en) 2004-11-22 2006-05-25 Sleeper Geoffrey P Adjustable sealing nasal cannula
EP1671670A1 (fr) 2004-12-14 2006-06-21 STX Sprl Appareil pour l'electro-inhibition des muscles de la face
US20070250119A1 (en) 2005-01-11 2007-10-25 Wicab, Inc. Systems and methods for altering brain and body functions and for treating conditions and diseases of the same
US8109981B2 (en) 2005-01-25 2012-02-07 Valam Corporation Optical therapies and devices
US20120053648A1 (en) 2005-02-08 2012-03-01 Rolf Neher Systems and methods for smoking cessation.
US20070248930A1 (en) 2005-02-17 2007-10-25 Biolux Research Ltd. Light therapy apparatus and methods
US8224444B2 (en) 2005-02-18 2012-07-17 Bio Control Medical (B.C.M.) Ltd. Intermittent electrical stimulation
JP4597702B2 (ja) 2005-02-24 2010-12-15 ピジョン株式会社 口唇閉鎖具
US20070060954A1 (en) 2005-02-25 2007-03-15 Tracy Cameron Method of using spinal cord stimulation to treat neurological disorders or conditions
US7555345B2 (en) 2005-03-11 2009-06-30 Medtronic, Inc. Implantable neurostimulator device
US7565204B2 (en) 2005-03-24 2009-07-21 Alfred E. Mann Foundation For Scientific Research Implantable device for controlling received power by a power receiving unit therein
US8082033B2 (en) 2005-04-13 2011-12-20 The Cleveland Clinic Foundation System and method for providing a waveform for stimulating biological tissue
US20090156581A1 (en) 2005-04-15 2009-06-18 Board Of Trustrees Of Michigan State University Aminergic pharmaceutical compositions and methods
US20060235430A1 (en) 2005-04-15 2006-10-19 Intralens Vision, Inc. Corneal implant injector assembly and methods of use
JP2006311917A (ja) * 2005-05-09 2006-11-16 Shozo Terauchi 低周波電気刺激装置
US7551958B2 (en) 2005-05-24 2009-06-23 Cardiac Pacemakers, Inc. Safety control system for implantable neural stimulator
US7947076B2 (en) 2005-06-03 2011-05-24 Medtronic Xomed, Inc. Nasal valve treatment method and apparatus
US20060276738A1 (en) 2005-06-06 2006-12-07 Becker Bruce B Lacrimal drainage bypass device and method
US8204607B2 (en) 2005-06-09 2012-06-19 Medtronic, Inc. Implantable medical lead
WO2006135753A1 (en) 2005-06-09 2006-12-21 Medtronic, Inc. Introducer for therapy delivery elements
US8606362B2 (en) 2005-07-08 2013-12-10 Boston Scientific Neuromodulation Corporation Current output architecture for an implantable stimulator device
DE102005032989A1 (de) 2005-07-14 2007-01-25 Imi Intelligent Medical Implants Ag Extraokulares Epiretinal-Implantat
US20070016256A1 (en) 2005-07-18 2007-01-18 Korb Donald R Method and apparatus for treating gland dysfunction
WO2013003594A2 (en) 2011-06-28 2013-01-03 Tearscience, Inc. Methods and systems for treating meibomian gland dysfunction using radio-frequency energy
US7981095B2 (en) 2005-07-18 2011-07-19 Tearscience, Inc. Methods for treating meibomian gland dysfunction employing fluid jet
US9962558B2 (en) 2005-08-05 2018-05-08 Gholam A. Peyman Methods to regulate polarization and enhance function of cells
US20070031341A1 (en) * 2005-08-08 2007-02-08 Dimauro Thomas M Methods of delivering therapeutics to the brain
JP2007044323A (ja) 2005-08-11 2007-02-22 Nidek Co Ltd 視覚再生補助装置
US8005526B2 (en) 2005-08-31 2011-08-23 The Regents Of The University Of Michigan Biologically integrated electrode devices
US7805202B2 (en) 2005-09-30 2010-09-28 Boston Scientific Neuromodulation Corporation Implantable electrodes and insertion methods and tools
US8676324B2 (en) * 2005-11-10 2014-03-18 ElectroCore, LLC Electrical and magnetic stimulators used to treat migraine/sinus headache, rhinitis, sinusitis, rhinosinusitis, and comorbid disorders
US7729758B2 (en) 2005-11-30 2010-06-01 Boston Scientific Neuromodulation Corporation Magnetically coupled microstimulators
US7444181B2 (en) 2005-12-14 2008-10-28 Boston Scientific Neuromodulation Corporation Techniques for sensing and adjusting a compliance voltage in an implantable stimulator device
US20080108867A1 (en) 2005-12-22 2008-05-08 Gan Zhou Devices and Methods for Ultrasonic Imaging and Ablation
EP1979042A4 (en) 2006-01-16 2009-12-30 Continence Control Systems Int STIMULATOR FOR CONTROLLING A BODILY FUNCTION
CN103284833B (zh) 2006-01-17 2016-06-29 创森德医疗设备公司 青光眼治疗装置
WO2007098200A2 (en) 2006-02-16 2007-08-30 Imthera Medical, Inc. An rfid-based apparatus, system, and method for therapeutic treatment of obstructive sleep apnea
US8118752B2 (en) 2006-02-16 2012-02-21 The Board Of Trustees Of The University Of Illinois Apparatus and methods for mapping retinal function
IES20060134A2 (en) 2006-02-23 2007-09-05 Sensor Technologies And Device Biomedical surface electrode
US20070219600A1 (en) 2006-03-17 2007-09-20 Michael Gertner Devices and methods for targeted nasal phototherapy
US20070237797A1 (en) 2006-03-28 2007-10-11 Gholam A. Peyman Neural Conduit Agent Dissemination
US20070250135A1 (en) 2006-04-21 2007-10-25 Bartz-Schmidt Karl U Compound subretinal prostheses with extra-ocular parts and surgical technique therefore
US20070255333A1 (en) 2006-04-28 2007-11-01 Medtronic, Inc. Neuromodulation therapy for perineal or dorsal branch of pudendal nerve
US9314369B2 (en) 2006-05-15 2016-04-19 Tearscience, Inc. System for inner eyelid treatment of meibomian gland dysfunction
US20070276314A1 (en) 2006-05-26 2007-11-29 Becker Bruce B Nasolacrimal duct probing, intubating and irrigating device
US20090204142A1 (en) 2006-05-26 2009-08-13 Becker Bruce B Nasolacrimal system surgical tool and method
US20070299462A1 (en) 2006-06-23 2007-12-27 Becker Bruce B Nasolacrimal system irrigation and dilatation tool
US8231218B2 (en) 2006-06-15 2012-07-31 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US8311634B2 (en) 2006-06-16 2012-11-13 Second Sight Medical Products Inc. Apparatus and method for electrical stimulation of human retina
US20070299420A1 (en) 2006-06-23 2007-12-27 Minu, L.L.C. Delivery of an agent using iontophoresis
US8080047B2 (en) 2006-08-01 2011-12-20 Mesure Technology Co., Ltd. Light therapy device
US8295529B2 (en) 2006-08-28 2012-10-23 Bcinet, Inc. Gaming headset with integrated microphone and adapted for olfactory stimulation
JP2008055000A (ja) 2006-08-31 2008-03-13 Nidek Co Ltd 視覚再生補助装置
PL2064337T3 (pl) 2006-09-20 2012-12-31 Genzyme Corp Oparty na FACS i białku reporterowym układ do wysokowydajnego opracowywania białek terapeutycznych
US8249723B2 (en) 2006-09-27 2012-08-21 Huntington Medical Research Institutes Apparatus and method for treating obstructive sleep apnea
US20080082057A1 (en) 2006-09-29 2008-04-03 Korb Donald R Method and apparatus for diagnosing meibomian gland dysfunction
US20080082131A1 (en) 2006-10-03 2008-04-03 Myriam Ivette Llanos Facial Nerve Stimulator (FNS)
DE102006048819A1 (de) 2006-10-10 2008-04-17 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Vorrichtung mit einem Grundkörper
EP2478931B1 (en) 2006-10-13 2015-12-30 Cyberonics, Inc. Obstructive sleep apnea treatment device
AU2006350059B2 (en) 2006-10-18 2010-08-26 Boston Scientific Neuromodulation Corporation Multi-electrode implantable stimulator device with a single current path decoupling capacitor
US10856904B2 (en) 2006-11-30 2020-12-08 Medtronic, Inc. Flexible introducer
WO2008084063A1 (en) 2007-01-09 2008-07-17 Fovea Pharmaceuticals Apparatus for intra-ocular injection
DE102007002783A1 (de) 2007-01-18 2008-08-07 Bayer Materialscience Ag Hydrogele aus hydrophilen Polyurethan(meth)acrylaten
AR064985A1 (es) 2007-01-22 2009-05-06 E Vision Llc Lente electroactivo flexible
US20080183242A1 (en) 2007-01-29 2008-07-31 Nidek Co., Ltd. Electrical stimulation method for vision improvement
JP4970069B2 (ja) 2007-01-30 2012-07-04 株式会社ニデック 視覚再生補助装置
US8755896B2 (en) 2007-02-05 2014-06-17 University Of Southern California Treatment of consumption disorders with biostimulation
WO2008101225A2 (en) 2007-02-16 2008-08-21 Second Sight Medical Products, Inc. Flexible circuit electrode array with wire or film support
RU2338492C1 (ru) * 2007-02-21 2008-11-20 Андрей Анатольевич Бессонов Способ лечения недостаточности слезопродукции при синдроме сухости глаза
US7949403B2 (en) 2007-02-27 2011-05-24 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of neurological disorders
US8406877B2 (en) * 2007-03-19 2013-03-26 Cardiac Pacemakers, Inc. Selective nerve stimulation with optionally closed-loop capabilities
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
US7879032B1 (en) 2007-04-16 2011-02-01 Ellman International, Inc. Disposable electrosurgical handpiece
US20080269648A1 (en) 2007-04-30 2008-10-30 Ultra License Holdings, Inc. Method for increasing saliva and tear production with ultrasound
WO2008143955A2 (en) 2007-05-14 2008-11-27 The Regents Of The University Of Colorado Laser fusion of tissue layers
SE531172C2 (sv) 2007-05-16 2009-01-13 Rhinomed Ab Vibrationsanordning avsedd att användas i kroppskaviteter, företrädesvis i näshålan
US8032222B2 (en) 2007-06-19 2011-10-04 Loushin Michael K H Device for electrically and mechanically stimulating a compartment in a body
US7758190B2 (en) 2007-06-20 2010-07-20 Tearscience, Inc. Tear film measurement
US7676276B2 (en) 2007-07-02 2010-03-09 Manuel L Karell Stimulator combined with an intranasal respiratory method and device for improved breathing
US8145322B1 (en) 2007-07-19 2012-03-27 Second Sight Medical Products, Inc. Flexible circuit electrode array device and a method for backside processing of a flexible circuit electrode device
ES2602989T3 (es) 2007-07-20 2017-02-23 Boston Scientific Neuromodulation Corporation Sistema de estimulación para controlar el orden de reclutamiento neuronal y el efecto clínico
EP2977080B1 (en) 2007-07-27 2024-02-14 Cortigent, Inc. Implantable device for the brain
US8805510B2 (en) 2007-08-02 2014-08-12 University of Pittsburgh—of the Commonwealth System of Higher Education Methods and systems for achieving a physiological response by pudendal nerve stimulation and blockade
US8088120B2 (en) 2007-09-05 2012-01-03 Maya Worsoff Method and apparatus for alleviating nasal congestion
RU2010112417A (ru) 2007-09-07 2011-10-10 Клт Плаг Диливери, Инк. (Us) Обнаружение лакримальных имплантатов
US8315689B2 (en) 2007-09-24 2012-11-20 MRI Interventions, Inc. MRI surgical systems for real-time visualizations using MRI image data and predefined data of surgical tools
US8019419B1 (en) 2007-09-25 2011-09-13 Dorin Panescu Methods and apparatus for leadless, battery-less, wireless stimulation of tissue
CN101896526B (zh) 2007-10-03 2013-09-11 新型聚合物生物材料有限公司 高模量聚氨酯和聚氨酯/脲组合物
US20090093446A1 (en) * 2007-10-05 2009-04-09 Winston Laboratories, Inc. Method for alleviating keratoconjunctivitis sicca
BRPI0818654A2 (pt) 2007-10-09 2015-04-07 Imthera Medical Inc Aparelho, sistema e método para estimulação seletiva
US7873421B2 (en) * 2007-10-23 2011-01-18 Manuel L Karell Nasal dilator adapted to provide electrical stimulation
US20090157142A1 (en) 2007-11-26 2009-06-18 Microtransponder Inc. Implanted Driver with Charge Balancing
US8457757B2 (en) 2007-11-26 2013-06-04 Micro Transponder, Inc. Implantable transponder systems and methods
DE112008003192T5 (de) 2007-11-26 2010-10-07 Micro-Transponder, Inc., Dallas Übertragungsspulenarchitektur
GB2456002A (en) 2007-12-31 2009-07-01 William M Hung A method for the manufacture of silicone hydrogel contact lenses in which filler material is introduced, the lens formed and the filler extracted.
US8165694B2 (en) 2008-01-29 2012-04-24 Boston Scientific Neuromodulation Corporation Thermal management of implantable medical devices
USD614303S1 (en) 2008-02-06 2010-04-20 Tearscience, Inc. Eye treatment apparatus
USD617443S1 (en) 2008-02-06 2010-06-08 Tearscience, Inc. Eye treatment goggles
USD613408S1 (en) 2008-02-06 2010-04-06 Tearscience, Inc. Eye treatment head gear
JP5343120B2 (ja) 2008-03-20 2013-11-13 アイエムアイ インテリジェント メディカル インプランツ アクチエンゲゼルシャフト 網膜インプラント用電力供給装置
US7832355B2 (en) 2008-04-01 2010-11-16 Frances Kay Mills Animal feeder
US8543211B2 (en) 2008-04-10 2013-09-24 ElectroCore, LLC Methods and apparatus for deep brain stimulation
US7846124B2 (en) 2008-05-07 2010-12-07 Becker Bruce B Punctal anchor for lacrimal stent, introducer tool and method
US8805518B2 (en) 2008-05-09 2014-08-12 Medtronic, Inc. Peripheral nerve field stimulation control
US8855777B2 (en) 2008-05-09 2014-10-07 Medtronic, Inc. Programming techniques for peripheral nerve field stimulation
EP2283363A1 (en) 2008-05-20 2011-02-16 Cantimer Incorporated Methods, systems and devices for analyzing a surfactant-treated biological fluid sample
DE102008002228A1 (de) 2008-06-05 2009-12-10 Biotronik Crm Patent Ag Langgestrecktes Implantat mit externer Energieeinkopplung
US8626306B2 (en) 2008-06-12 2014-01-07 Second Sight Medical Products, Inc. Visual prosthesis for control of spatiotemporal interactions
ITRM20080309A1 (it) 2008-06-12 2009-12-13 Massimo Filippello Metodo di trattamento oculare per la prevenzione della presbiopia e del glaucoma e mezzi per effettuare tale trattamento
NL2001698C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Cardioverter / defibrillator.
NL2001697C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Nose stimulator for producing a stimulation signal to a nose.
US8945086B2 (en) 2008-07-01 2015-02-03 Bruce Becker Retrobulbar needle and methods of use
US20100274224A1 (en) 2008-07-08 2010-10-28 Qlt Plug Delivery, Inc. Lacrimal implant body including comforting agent
WO2010027743A1 (en) 2008-08-25 2010-03-11 Alpha Synergy Development, Inc. Pharmaceutical compositions and methods for the treatment of dry eye
JP2010051562A (ja) 2008-08-28 2010-03-11 Tohoku Univ 生体の深部刺激方法及び生体深部の刺激装置
WO2010033804A1 (en) 2008-09-19 2010-03-25 Avedro, Inc. Eye therapy system
JP2012504472A (ja) 2008-10-01 2012-02-23 アヴェドロ・インコーポレーテッド 眼治療システム
WO2010048422A2 (en) 2008-10-22 2010-04-29 Advanced Neuromodulation Systems, Inc. Method for processing electrodes for stimulation lead
US8448273B2 (en) 2008-10-29 2013-05-28 Smartsilk Corporation Inc. Pillow and cover for a pillow
NZ593201A (en) 2008-12-05 2013-05-31 Semprus Biosciences Corp Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
EP2373234A1 (en) 2008-12-16 2011-10-12 Aardvark Medical, Inc. Methods and systems for delivery of fluids, aerosols and acoustic energy to tissue surfaces, cavities and obstructed passages such as intranasal ostia
DE202008016711U1 (de) 2008-12-18 2010-05-12 Metabowerke Gmbh Werkzeugmaschine, insbesondere Kapp- und Gehrungssäge
USD614774S1 (en) 2008-12-18 2010-04-27 Tearscience, Inc. Ocular imaging apparatus
WO2010069317A1 (en) 2008-12-19 2010-06-24 Neurodan A/S Bursts of electrical pulses in the treatment of pelvic disorders by electrical nerve stimulation
EP2361033A4 (en) 2008-12-22 2012-09-12 Integrated Sensing Systems Inc WIRELESS DYNAMIC POWER CONTROL OF AN IMPLANTABLE SENSOR DEVICE AND METHODS
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
WO2010076904A1 (en) 2008-12-29 2010-07-08 Seung-Won Jeong Rhinitis laser-aroma therapy apparatus
US8235932B2 (en) 2009-01-09 2012-08-07 Becker Bruce B Side-by-side lacrimal intubation threader and method
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9233254B2 (en) 2009-02-17 2016-01-12 Boston Scientific Neuromodulation Corporation Selectable boost converter and charge pump for compliance voltage generation in an implantable stimulator device
WO2010099818A1 (en) 2009-03-03 2010-09-10 Ao Technology Ag Thermoreversible polysaccharide hydrogel
CN101503491B (zh) 2009-03-10 2011-11-30 海昌隐形眼镜有限公司 一种高透氧氟硅氧烷水凝胶接触镜材料及其制备方法
WO2010115109A1 (en) 2009-04-02 2010-10-07 Avedro, Inc. Eye therapy system
WO2010123704A2 (en) 2009-04-24 2010-10-28 Medtronic, Inc. Incontinence therapy
CA2764477A1 (en) 2009-06-05 2010-12-09 Aciex Therapeutics, Inc. Ophthalmic formulations, methods of manufacture, and methods of using same
US20100318159A1 (en) 2009-06-12 2010-12-16 Boston Scientific Neuromodulation Corporation Miniature remote controller for implantable medical device
US9320533B2 (en) 2009-07-21 2016-04-26 Leonard V. Covello Devices and methods for minimally invasive access to sinuses and treatment of sinusitis
JP5578540B2 (ja) 2009-07-31 2014-08-27 株式会社ニデック 視覚再生補助装置及び視覚再生補助装置の製造方法
US8283890B2 (en) 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
AU2009222439B2 (en) 2009-09-28 2011-07-21 Cochlear Limited Method and circuitry for measurement and control of stimulation current
EP2485800B1 (en) 2009-10-05 2017-12-06 The Regents of The University of California Extracranial implantable devices and systems for the treatment of neuropsychiatric disorders
USD638128S1 (en) 2009-10-06 2011-05-17 Tearscience, Inc. Ocular device design
US8571677B2 (en) * 2009-10-21 2013-10-29 Medtronic, Inc. Programming techniques for stimulation with utilization of case electrode
IL202462A0 (en) 2009-12-02 2010-06-30 Feldman Joseph Device for treatment of rhinitis by biostimulative illumination
US8622993B2 (en) 2009-12-18 2014-01-07 Healthpartners Research Foundation Device and method for delivering therapeutic substances to the maxillary sinus of a patient
US8620442B2 (en) 2010-01-27 2013-12-31 Second Sight Medical Products, Inc. Multi-electrode integration in a visual prosthesis
US20110202121A1 (en) 2010-02-16 2011-08-18 Shin-Heng Wen Electrical nerve stimulator
WO2011103291A1 (en) 2010-02-18 2011-08-25 Dow Corning Corporation Siloxane surface-modified hydrogel and hydrogel microparticle compositions
WO2011109739A1 (en) 2010-03-05 2011-09-09 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
TWM389271U (en) 2010-03-23 2010-09-21 Guo-Ren Ye Healthcare eyeglasses
WO2011137298A2 (en) 2010-04-30 2011-11-03 Second Sight Medical Products,Inc. Improved biocompatible bonding method
US8364272B2 (en) 2010-04-30 2013-01-29 Medtronic, Inc. Brain stimulation programming
US9522980B2 (en) 2010-05-06 2016-12-20 Johnson & Johnson Vision Care, Inc. Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
US8968783B2 (en) 2010-05-27 2015-03-03 Covidien Lp Hydrogel implants with varying degrees of crosslinking
CA2801508C (en) 2010-06-04 2018-07-10 The Government of the United States of America as represented by the Secretary of Health and Human Services, Centers for Disease Control and Prevention Nasal aerosol delivery system
WO2011159527A2 (en) 2010-06-16 2011-12-22 Cardiac Pacemakers, Inc. Automatic neural stimulation titration sweep
MX2013000160A (es) 2010-07-05 2013-05-22 Reluceo Inc Polimeros superabsorbentes degradables.
JP5776165B2 (ja) 2010-11-05 2015-09-09 株式会社ニデック 生体組織用刺激回路
JP2012115545A (ja) 2010-12-02 2012-06-21 Nidek Co Ltd 生体組織用刺激回路
US9937355B2 (en) 2010-11-08 2018-04-10 Zoll Medical Corporation Remote medical device alarm
AU2011328900B2 (en) * 2010-11-16 2015-03-19 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for treatment of dry eye
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
WO2012075192A2 (en) 2010-11-30 2012-06-07 The Regents Of The University Of California Pulse generator for cranial nerve stimulation
US20120133887A1 (en) 2010-11-30 2012-05-31 Optovue, Inc. Tear film and tear meniscus dynamics with time-lapse optical coherence tomography
US20110081333A1 (en) * 2010-12-10 2011-04-07 Shantha Totada R Apparatus and system for treatment and prevention of bags under eyes
US8706233B2 (en) 2011-01-28 2014-04-22 Medtronic, Inc. Stimulation therapy including substantially simultaneous bilateral stimulation
EP2497530A3 (en) 2011-03-07 2013-06-19 Giancarlo Barolat Modular nerve stimulation system
EP2691149B1 (en) 2011-03-28 2019-02-27 Med-El Elektromedizinische Geraete GmbH System for treating apnea using evoked swallow
JP5419174B2 (ja) 2011-03-28 2014-02-19 国立大学法人 新潟大学 嚥下誘発装置
CN103747834B (zh) * 2011-04-07 2016-03-02 奥库利维公司 刺激装置和方法
EP2707087B1 (en) 2011-05-13 2018-05-02 Saluda Medical Pty Limited Method and apparatus for controlling a neural stimulus - e
US9764140B2 (en) * 2011-05-17 2017-09-19 Boston Scientific Neuromodulation Corporation Display of region of activation in neurostimulation programming screen
US8944052B2 (en) 2011-05-26 2015-02-03 Ivan Osorio Apparatus and methods for delivery of therapeutic agents to mucous or serous membrane
US20120316557A1 (en) 2011-06-08 2012-12-13 Tyco Healthcare Group Lp Septoplasty Instrument
EP4233755A3 (en) * 2011-06-14 2023-10-25 Aerin Medical, Inc. Device for treating nasal airways
US8986301B2 (en) 2012-06-13 2015-03-24 Aerin Medical Inc. Methods and devices to treat nasal airways
US20120330376A1 (en) 2011-06-27 2012-12-27 Equine OrthoCare, LLC Systems and methods for making and using electrical stimulation systems for providing therapy to large animals
MX348560B (es) 2011-08-26 2017-06-20 Scerbo Louis Aparato para el rejuvenecimiento facial.
US8965511B2 (en) 2011-08-30 2015-02-24 Valencia Technologies Corporation Implantable electroacupuncture system and method for reducing hypertension
EP2758126B1 (en) * 2011-09-22 2020-01-01 Djo, Llc Devices and system for treating pain with electrical stimulation
US8996125B2 (en) 2011-09-23 2015-03-31 Valencia Technologies Corporation Implantable electroacupuncture system and method for treating cardiovascular disease
US9173811B2 (en) 2011-09-29 2015-11-03 Valencia Technologies Corporation Implantable electroacupuncture system and method for treating depression and similar mental conditions
EP2766087A4 (en) 2011-10-11 2015-05-06 Univ Duke NON-REGULAR ELECTRICAL STIMULATION PATTERNS FOR THE TREATMENT OF NEUROLOGICAL DISEASES
DE102011055844B4 (de) * 2011-11-29 2014-01-02 Okuvision Gmbh Stimulationselektrode für eine Vorrichtung zur Elektrostimulation des Auges
CN104144670B (zh) 2011-12-16 2016-10-19 考地特医疗Ab公司 Ans刺激
USD681839S1 (en) 2011-12-16 2013-05-07 Micromode Medical Limited Electrostimulation device
US9724230B2 (en) 2012-01-04 2017-08-08 Sight Sciences, Inc. Dry eye treatment apparatus and methods
CN104508343B (zh) 2012-01-26 2016-11-16 Med-El电气医疗器械有限公司 用于治疗咽部障碍的神经监测方法和系统
US9549966B2 (en) 2012-02-21 2017-01-24 Massachusetts Eye & Ear Infirmary Inflammatory eye disorders
US9314399B2 (en) 2012-03-06 2016-04-19 Valencia Technologies Corporation Implantable electroacupuncture system and method for treating dyslipidemia and obesity
US20130253387A1 (en) 2012-03-08 2013-09-26 Sonitec, LLC Vibratory energy systems and methods for occluded body cavities
US20130261706A1 (en) * 2012-03-30 2013-10-03 Neuropace, Inc. Systems and methods for applying rapid sequential electrode stimulation
US9623247B2 (en) 2012-04-17 2017-04-18 The Ohio State University Neuromodulatory method for treating chronic or refractory rhinitis
US20130270491A1 (en) 2012-04-17 2013-10-17 Ik-Ro PARK Conductive hydrogel and method of preparing the same
US20130274824A1 (en) 2012-04-17 2013-10-17 The Ohio State University Neuromodulatory method for treating chronic rhinosinusitis
JP5927014B2 (ja) 2012-04-18 2016-05-25 Hoya株式会社 湿潤性表面を有するシリコーンハイドロゲルソフトコンタクトレンズ
WO2013162793A1 (en) 2012-04-27 2013-10-31 Boston Scientific Neuromodulation Timing channel circuitry for creating pulses in an implantable stimulator device
WO2013165697A1 (en) 2012-04-30 2013-11-07 Vigilant Medical Solutions, Inc. Indirect and non-invasive trigeminal neuromodulation for the treatment of disease
WO2013166353A1 (en) 2012-05-04 2013-11-07 Alcon Research, Ltd. Method for diagnosing dry eye and meibomian gland disease using meibomian secretions
US9700721B2 (en) 2012-05-14 2017-07-11 Autonomic Technologies, Inc. Stimulation method for treatment of ocular conditions
US20120323214A1 (en) 2012-05-16 2012-12-20 Totada R Shantha Alzheimer's disease treatment with multiple therapeutic agents delivered to the olfactory region through a special delivery catheter and iontophoresis
US10232184B2 (en) 2012-05-18 2019-03-19 The Guy P. Curtis And Frances L. Curtis Trust Extracorporeal unit for inspecting the insulation of an electrical wire of an implanted medical device
US20120234332A1 (en) 2012-06-01 2012-09-20 Shantha Totada R Snoring and obstructive sleep apnea prevention and treatment device
US9968297B2 (en) 2012-06-14 2018-05-15 Medibotics Llc EEG glasses (electroencephalographic eyewear)
WO2014153218A1 (en) * 2013-03-14 2014-09-25 Tyler Perryman Laura Devices and methods for treating craniofacial pain
US8903494B2 (en) 2012-11-26 2014-12-02 Thync, Inc. Wearable transdermal electrical stimulation devices and methods of using them
US9226818B2 (en) 2012-11-30 2016-01-05 Novartis Ag Sensors for triggering electro-active ophthalmic lenses
CN104797291B (zh) 2012-12-07 2017-09-12 美敦力公司 微创可植入神经刺激系统
EP2747158A1 (en) 2012-12-24 2014-06-25 Université Pierre et Marie Curie (Paris 6) Biocompatible carbon based electrode, its use and preparation process
US9174049B2 (en) 2013-01-27 2015-11-03 ElectroCore, LLC Systems and methods for electrical stimulation of sphenopalatine ganglion and other branches of cranial nerves
US10238534B2 (en) 2013-03-07 2019-03-26 Novartis Ag Systems and processes for eye moisturizing during ocular surgery
WO2014138709A1 (en) 2013-03-08 2014-09-12 Oculeve, Inc. Devices and methods for treating dry eye in animals
EP2967817B1 (en) 2013-03-12 2021-03-10 Oculeve, Inc. Implant delivery devices and systems
JP6795975B2 (ja) 2013-04-19 2020-12-02 オキュリーブ， インコーポレイテッド 鼻刺激デバイス及び方法
WO2014200864A1 (en) 2013-06-14 2014-12-18 University Of Houston System Accommodation stimulation and recording device
CN103467652B (zh) 2013-09-03 2015-08-26 东南大学 一种水凝胶接触镜及其制备方法
MX2016011118A (es) 2014-02-25 2016-12-05 Oculeve Inc Formulaciones de polimeros para estimulacion nasolagrimal.
AU358535S (en) 2014-04-18 2014-11-03 Oculeve Nasal stimulator device
US10317702B2 (en) 2014-06-13 2019-06-11 Verily Life Sciences Llc Failsafe operation of eye-mountable device
EP3171928B1 (en) 2014-07-25 2020-02-26 Oculeve, Inc. Stimulation patterns for treating dry eye
EP3177201B1 (en) 2014-08-10 2023-08-02 Autonomix Medical, Inc. Methods and systems for assessing neural activity in an eye
US10201451B2 (en) 2014-08-29 2019-02-12 Camras Vision Inc. Device and method for reducing intraocular pressure
US9699436B2 (en) 2014-09-16 2017-07-04 Microsoft Technology Licensing, Llc Display with eye-discomfort reduction
CA2965363A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Implantable nasal stimulator systems and methods
US9737712B2 (en) 2014-10-22 2017-08-22 Oculeve, Inc. Stimulation devices and methods for treating dry eye
EP3209370A4 (en) 2014-10-22 2018-05-30 Oculeve, Inc. Contact lens for increasing tear production
NZ773815A (en) 2015-03-16 2022-07-01 Magic Leap Inc Methods and systems for diagnosing and treating health ailments
CN107835706A (zh) 2015-06-16 2018-03-23 科罗拉多州立大学董事会·法人团体 用于眼泪刺激的鼻泪植入物和相关方法
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
US10918864B2 (en) 2016-05-02 2021-02-16 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US20180161579A1 (en) 2016-12-01 2018-06-14 Oculeve, Inc. Extranasal stimulation devices and methods
WO2018102535A1 (en) 2016-12-02 2018-06-07 Oculeve, Inc. Apparatus and method for dry eye forecast and treatment recommendation
JP6818080B2 (ja) * 2019-05-14 2021-01-20 日本曹達株式会社 培養装置、培養ユニット、および培養対象回収方法

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