JP6649358B2 - アンジオポエチン様４抗体および使用法 - Google Patents
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Biochemistry (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
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| US201462034409P | 2014-08-07 | 2014-08-07 | |
| US62/034,409 | 2014-08-07 | ||
| PCT/IB2015/055986 WO2016020880A2 (en) | 2014-08-07 | 2015-08-06 | Angiopoietin-like 4 antibodies and methods of use |
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| JP2020004261A Division JP2020075929A (ja) | 2014-08-07 | 2020-01-15 | アンジオポエチン様４抗体および使用法 |
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| JP2017529324A JP2017529324A (ja) | 2017-10-05 |
| JP2017529324A5 JP2017529324A5 (OSRAM) | 2018-09-06 |
| JP6649358B2 true JP6649358B2 (ja) | 2020-02-19 |
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| JP2017506693A Active JP6649358B2 (ja) | 2014-08-07 | 2015-08-06 | アンジオポエチン様４抗体および使用法 |
| JP2020004261A Pending JP2020075929A (ja) | 2014-08-07 | 2020-01-15 | アンジオポエチン様４抗体および使用法 |
| JP2022007104A Active JP7397104B2 (ja) | 2014-08-07 | 2022-01-20 | アンジオポエチン様４抗体および使用法 |
| JP2023202489A Active JP7695330B2 (ja) | 2014-08-07 | 2023-11-30 | アンジオポエチン様４抗体および使用法 |
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| JP2020004261A Pending JP2020075929A (ja) | 2014-08-07 | 2020-01-15 | アンジオポエチン様４抗体および使用法 |
| JP2022007104A Active JP7397104B2 (ja) | 2014-08-07 | 2022-01-20 | アンジオポエチン様４抗体および使用法 |
| JP2023202489A Active JP7695330B2 (ja) | 2014-08-07 | 2023-11-30 | アンジオポエチン様４抗体および使用法 |
Country Status (31)
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| AP (1) | AP2017009721A0 (OSRAM) |
| AR (1) | AR101486A1 (OSRAM) |
| AU (1) | AU2015300685B2 (OSRAM) |
| BR (1) | BR112017002173B1 (OSRAM) |
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| CO (1) | CO2017001087A2 (OSRAM) |
| CR (1) | CR20170040A (OSRAM) |
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| MA (1) | MA40512A (OSRAM) |
| MX (2) | MX390418B (OSRAM) |
| NZ (1) | NZ728425A (OSRAM) |
| PE (1) | PE20170287A1 (OSRAM) |
| PH (1) | PH12017500156A1 (OSRAM) |
| PL (1) | PL3177642T3 (OSRAM) |
| PT (1) | PT3177642T (OSRAM) |
| SG (2) | SG10201805646WA (OSRAM) |
| TN (1) | TN2017000019A1 (OSRAM) |
| TW (1) | TWI675043B (OSRAM) |
| UY (1) | UY36262A (OSRAM) |
| WO (1) | WO2016020880A2 (OSRAM) |
Families Citing this family (8)
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| TW201613977A (en) | 2014-08-07 | 2016-04-16 | Novartis Ag | Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use |
| TN2017000019A1 (en) | 2014-08-07 | 2018-07-04 | Novartis Ag | Angiopoietin-like 4 antibodies and methods of use. |
| GB2569144B (en) * | 2017-12-06 | 2021-06-16 | Proimmune Ltd | Method for screening the activity of mutated expressed polypeptides |
| US11787857B2 (en) * | 2018-02-02 | 2023-10-17 | Bio-Techne Corporation | Compounds that modulate the interaction of VISTA and VSIG3 and methods of making and using |
| AU2020245031A1 (en) * | 2019-03-26 | 2021-10-21 | Janssen Pharmaceutica Nv | Antibodies to pyroglutamate amyloid-β and uses thereof |
| JP2025512749A (ja) * | 2022-03-16 | 2025-04-22 | インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） | 感染症の新しい治療法 |
| EP4518969A1 (en) * | 2022-05-02 | 2025-03-12 | Novo Nordisk A/S | Novel anti-angptl3 antibodies suitable for high concentration compositions and subcutaneous administration |
| WO2025166073A1 (en) * | 2024-01-31 | 2025-08-07 | Alector Llc | Compositions comprising anti-sortilin antibodies and uses thereof |
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