MA55491A - Anticorps anti-pyroglutamate-amyloïde bêta et leurs utilisations - Google Patents
Anticorps anti-pyroglutamate-amyloïde bêta et leurs utilisationsInfo
- Publication number
- MA55491A MA55491A MA055491A MA55491A MA55491A MA 55491 A MA55491 A MA 55491A MA 055491 A MA055491 A MA 055491A MA 55491 A MA55491 A MA 55491A MA 55491 A MA55491 A MA 55491A
- Authority
- MA
- Morocco
- Prior art keywords
- pyroglutamate
- amyloid beta
- beta antibodies
- antibodies
- amyloid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962823785P | 2019-03-26 | 2019-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA55491A true MA55491A (fr) | 2022-02-09 |
Family
ID=70008544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA055491A MA55491A (fr) | 2019-03-26 | 2020-03-25 | Anticorps anti-pyroglutamate-amyloïde bêta et leurs utilisations |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11236155B2 (fr) |
| EP (1) | EP3946603A1 (fr) |
| JP (1) | JP2022526528A (fr) |
| KR (1) | KR20210143858A (fr) |
| CN (1) | CN113891746A (fr) |
| AU (1) | AU2020245031A1 (fr) |
| BR (1) | BR112021019107A2 (fr) |
| CA (1) | CA3134785A1 (fr) |
| CL (2) | CL2021002473A1 (fr) |
| CO (1) | CO2021014028A2 (fr) |
| CR (1) | CR20210492A (fr) |
| DO (1) | DOP2021000199A (fr) |
| EA (1) | EA202192606A1 (fr) |
| EC (1) | ECSP21079184A (fr) |
| IL (1) | IL286634A (fr) |
| JO (1) | JOP20210265A1 (fr) |
| MA (1) | MA55491A (fr) |
| MX (1) | MX2021011715A (fr) |
| PE (1) | PE20212266A1 (fr) |
| SG (1) | SG11202110504XA (fr) |
| WO (1) | WO2020193644A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112023001061A2 (pt) | 2020-07-23 | 2023-04-04 | Othair Prothena Ltd | Anticorpos antiabeta |
| AR127498A1 (es) * | 2021-10-28 | 2024-01-31 | Abbvie Inc | ANTICUERPOS ANTI-b AMILOIDE Y MÉTODOS DE USO DE LOS MISMOS |
| WO2023170295A1 (fr) * | 2022-03-11 | 2023-09-14 | Janssen Pharmaceutica Nv | Anticorps multispécifiques et leurs utilisations |
| TW202400636A (zh) * | 2022-03-11 | 2024-01-01 | 比利時商健生藥品公司 | 多特異性抗體及其用途(一) |
| TW202346355A (zh) * | 2022-03-11 | 2023-12-01 | 比利時商健生藥品公司 | 多特異性抗體及其用途(二) |
| WO2024133925A1 (fr) | 2022-12-22 | 2024-06-27 | Bioarctic Ab | Anticorps se liant à abêtape3 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US5587458A (en) | 1991-10-07 | 1996-12-24 | Aronex Pharmaceuticals, Inc. | Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof |
| US5642870A (en) | 1992-08-05 | 1997-07-01 | Sargis; Ike | Switch stand |
| US5761894A (en) | 1996-09-25 | 1998-06-09 | Magic Circle Corporation | Grass striping attachment for lawn mowers |
| US9907485B2 (en) | 2004-10-15 | 2018-03-06 | Brainlab Ag | Targeted immunization and plaque destruction against Alzheimer's disease |
| PE20061152A1 (es) * | 2004-12-15 | 2006-10-13 | Neuralab Ltd | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
| CN101432302A (zh) | 2005-11-30 | 2009-05-13 | 艾博特公司 | 抗－Aβ球聚体抗体，其抗原结合部分，相应的杂交瘤、核酸、载体、宿主细胞，生产所述抗体的方法，包含所述抗体的组合物，所述抗体的应用以及使用所述抗体的方法 |
| IL199534A (en) | 2007-01-05 | 2013-01-31 | Univ Zuerich | An isolated human antibody capable of detecting a neoepitope in a disease-related protein, a polynucleotide encoding an antibody, a vector containing the polynucleotide, a host cell containing the polynucleotide or vector, a preparation containing the antibody and related methods and uses. |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| AU2009269700B2 (en) | 2008-07-09 | 2015-07-16 | University Of Zurich | Method of promoting neurogenesis |
| EP3338795A1 (fr) | 2008-07-21 | 2018-06-27 | Probiodrug AG | Dosage d'anticorps de diagnostic |
| DK2462161T3 (en) | 2009-08-06 | 2017-06-06 | Immunas Pharma Inc | Antibodies specifically binding to A-beta oligomers and their use |
| WO2011106297A2 (fr) * | 2010-02-23 | 2011-09-01 | Genentech, Inc. | Compositions et méthodes pour le diagnostic et le traitement d'une tumeur |
| WO2011151076A2 (fr) * | 2010-06-04 | 2011-12-08 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Anticorps monoclonaux ciblant des oligomères aβ |
| RS54685B1 (en) | 2010-08-12 | 2016-08-31 | Eli Lilly And Company | ANTI-N3pGlu AMILOID BETA PEPTID ANTIBODIES AND THEIR USES |
| WO2012021475A2 (fr) | 2010-08-12 | 2012-02-16 | Eli Lilly And Company | ANTICORPS CONTRE LE PEPTIDE N3pGLU AMYLOÏDE BÊTA ET LEURS UTILISATIONS |
| EP2511296A1 (fr) | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Anticorps, kit et procédé pour déterminer des peptides amyloïdes |
| ITRM20120383A1 (it) | 2012-03-20 | 2013-09-21 | Uni Degli Studi Di Milano B Icocca | Metodo e kit per la rivelazione di anticorpi. |
| WO2015175769A1 (fr) | 2014-05-15 | 2015-11-19 | Biogen Ma Inc. | Procédés de détection d'oligomères bêta-amyloïdes dans des échantillons biologiques |
| WO2015191825A1 (fr) | 2014-06-13 | 2015-12-17 | Biogen Ma Inc. | Méthodes pour la détection et la mesure de la protéine beta amyloïde dans des échantillons biologiques |
| PE20170287A1 (es) * | 2014-08-07 | 2017-04-05 | Novartis Ag | Anticuerpos anti-proteina similar a angiopoyetina 4 y metodos de uso |
| US20170363645A1 (en) | 2014-12-19 | 2017-12-21 | Probiodrug Ag | Novel Method for the Detection of pGlu-Abeta Peptides |
| NZ739181A (en) | 2015-07-16 | 2023-05-26 | Vivoryon Therapeutics N V | Anti-pyroglutamated amyloid beta humanized antibodies |
| JOP20170004B1 (ar) * | 2016-01-15 | 2022-09-15 | Lilly Co Eli | الأجسام المضادة لببتيد بيتا النشوي مضاد N3pGlu واستخداماته |
| TW201740954A (zh) | 2016-03-16 | 2017-12-01 | 美國禮來大藥廠 | 組合療法 |
| EP3249388A1 (fr) | 2016-05-23 | 2017-11-29 | Raman Health Technologies, S.L | Procédé de diagnostic de la maladie d'alzheimer |
| IL263433B2 (en) | 2016-06-07 | 2024-03-01 | Biogen Int Neuroscience Gmbh | Methods for treating Alzheimer's disease |
| CA3032692A1 (fr) | 2016-08-09 | 2018-02-15 | Eli Lilly And Company | Polytherapie a base d'anticorps pour le traitement de maladies neurodegeneratives |
| TWI669119B (zh) | 2016-10-21 | 2019-08-21 | 美國禮來大藥廠 | 組合療法 |
| TW201827467A (zh) | 2016-11-03 | 2018-08-01 | 比利時商健生藥品公司 | 焦穀胺酸類澱粉蛋白－β之抗體及其用途 |
| JOP20190247A1 (ar) | 2017-04-20 | 2019-10-20 | Lilly Co Eli | أجسام بيتا ببتيد النشوانية المضادة لـ N3pGlu واستخداماتها |
| IL270375B1 (en) * | 2017-05-02 | 2024-08-01 | Prothena Biosciences Ltd | Antibodies that recognize tau |
| PT3672631T (pt) | 2017-08-22 | 2023-05-23 | Biogen Ma Inc | Composições farmacêuticas contendo anticorpos anti-betaamiloide |
| AU2019346645A1 (en) * | 2018-09-27 | 2021-04-29 | Marengo Therapeutics, Inc. | CSF1R/CCR2 multispecific antibodies |
-
2020
- 2020-03-25 CR CR20210492A patent/CR20210492A/es unknown
- 2020-03-25 SG SG11202110504XA patent/SG11202110504XA/en unknown
- 2020-03-25 PE PE2021001598A patent/PE20212266A1/es unknown
- 2020-03-25 JO JOP/2021/0265A patent/JOP20210265A1/ar unknown
- 2020-03-25 MX MX2021011715A patent/MX2021011715A/es unknown
- 2020-03-25 CA CA3134785A patent/CA3134785A1/fr active Pending
- 2020-03-25 WO PCT/EP2020/058395 patent/WO2020193644A1/fr active Application Filing
- 2020-03-25 EA EA202192606A patent/EA202192606A1/ru unknown
- 2020-03-25 BR BR112021019107A patent/BR112021019107A2/pt unknown
- 2020-03-25 MA MA055491A patent/MA55491A/fr unknown
- 2020-03-25 JP JP2021557190A patent/JP2022526528A/ja active Pending
- 2020-03-25 US US16/829,029 patent/US11236155B2/en active Active
- 2020-03-25 EP EP20714579.8A patent/EP3946603A1/fr active Pending
- 2020-03-25 KR KR1020217034312A patent/KR20210143858A/ko active Search and Examination
- 2020-03-25 US US17/598,280 patent/US20220177560A1/en active Pending
- 2020-03-25 CN CN202080039618.2A patent/CN113891746A/zh active Pending
- 2020-03-25 AU AU2020245031A patent/AU2020245031A1/en active Pending
-
2021
- 2021-09-23 DO DO2021000199A patent/DOP2021000199A/es unknown
- 2021-09-23 CL CL2021002473A patent/CL2021002473A1/es unknown
- 2021-09-23 IL IL286634A patent/IL286634A/en unknown
- 2021-10-20 CO CONC2021/0014028A patent/CO2021014028A2/es unknown
- 2021-10-26 EC ECSENADI202179184A patent/ECSP21079184A/es unknown
- 2021-12-17 US US17/554,461 patent/US20220106387A1/en active Pending
-
2022
- 2022-09-29 CL CL2022002670A patent/CL2022002670A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112021019107A2 (pt) | 2021-11-30 |
| AU2020245031A1 (en) | 2021-10-21 |
| EP3946603A1 (fr) | 2022-02-09 |
| CL2022002670A1 (es) | 2023-03-31 |
| JOP20210265A1 (ar) | 2023-01-30 |
| US20220106387A1 (en) | 2022-04-07 |
| MX2021011715A (es) | 2021-12-10 |
| SG11202110504XA (en) | 2021-10-28 |
| US20220177560A1 (en) | 2022-06-09 |
| IL286634A (en) | 2021-10-31 |
| EA202192606A1 (ru) | 2022-01-24 |
| CN113891746A (zh) | 2022-01-04 |
| US11236155B2 (en) | 2022-02-01 |
| WO2020193644A1 (fr) | 2020-10-01 |
| CO2021014028A2 (es) | 2021-10-29 |
| CA3134785A1 (fr) | 2020-10-01 |
| ECSP21079184A (es) | 2021-11-30 |
| DOP2021000199A (es) | 2022-07-15 |
| KR20210143858A (ko) | 2021-11-29 |
| JP2022526528A (ja) | 2022-05-25 |
| CL2021002473A1 (es) | 2022-04-22 |
| CR20210492A (es) | 2021-11-19 |
| US20200308261A1 (en) | 2020-10-01 |
| PE20212266A1 (es) | 2021-11-30 |
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