AU1397895A - Peptide analogs of the activated platelet binding site on factor xi - Google Patents

Peptide analogs of the activated platelet binding site on factor xi

Info

Publication number
AU1397895A
AU1397895A AU13978/95A AU1397895A AU1397895A AU 1397895 A AU1397895 A AU 1397895A AU 13978/95 A AU13978/95 A AU 13978/95A AU 1397895 A AU1397895 A AU 1397895A AU 1397895 A AU1397895 A AU 1397895A
Authority
AU
Australia
Prior art keywords
factor
binding site
peptide analogs
activated platelet
platelet binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU13978/95A
Inventor
Frank A Baglia
Bradford A. Jameson
Peter N Walsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Temple University of Commonwealth System of Higher Education
Original Assignee
Thomas Jefferson University
Temple University of Commonwealth System of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University, Temple University of Commonwealth System of Higher Education filed Critical Thomas Jefferson University
Publication of AU1397895A publication Critical patent/AU1397895A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU13978/95A 1993-12-22 1994-12-02 Peptide analogs of the activated platelet binding site on factor xi Abandoned AU1397895A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17200293A 1993-12-22 1993-12-22
US172002 1993-12-22
PCT/US1994/013885 WO1995017420A1 (en) 1993-12-22 1994-12-02 Peptide analogs of the activated platelet binding site on factor xi

Publications (1)

Publication Number Publication Date
AU1397895A true AU1397895A (en) 1995-07-10

Family

ID=22625963

Family Applications (1)

Application Number Title Priority Date Filing Date
AU13978/95A Abandoned AU1397895A (en) 1993-12-22 1994-12-02 Peptide analogs of the activated platelet binding site on factor xi

Country Status (2)

Country Link
AU (1) AU1397895A (en)
WO (1) WO1995017420A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
KR101979134B1 (en) * 2008-10-15 2019-05-15 아이오니스 파마수티컬즈, 인코포레이티드 Modulation of factor 11 expression
WO2016020882A2 (en) 2014-08-07 2016-02-11 Novartis Ag Angiopoetin-like 4 (angptl4) antibodies and methods of use
PT3177642T (en) 2014-08-07 2022-02-14 Novartis Ag Angiopoietin-like 4 antibodies and methods of use
JOP20200312A1 (en) 2015-06-26 2017-06-16 Novartis Ag Factor xi antibodies and methods of use
TW201802121A (en) 2016-05-25 2018-01-16 諾華公司 Reversal binding agents for anti-factor XI/XIa antibodies and uses thereof
IL308980A (en) 2016-12-23 2024-01-01 Novartis Ag Factor xi antibodies and methods of use
PE20210393A1 (en) 2018-05-09 2021-03-02 Ionis Pharmaceuticals Inc COMPOUNDS AND METHODS FOR REDUCING THE EXPRESSION OF FXI

Also Published As

Publication number Publication date
WO1995017420A1 (en) 1995-06-29

Similar Documents

Publication Publication Date Title
AU4715493A (en) Peptide compounds
AU7043394A (en) Association peptides
AU6623894A (en) Therapeutic compounds
AU6360394A (en) Vasonatrin peptide and analogs thereof
AU5803394A (en) Mechanized directory assistance
AU7407594A (en) Therapeutic compositions comprising a polypeptide
AU3098289A (en) Hirudin peptides
AU7961094A (en) Picosulphate dosage form
AU671148C (en) Binding element
AU3588189A (en) Polypeptide compounds
HU9502041D0 (en) New peptide
AU3414689A (en) Therapeutic peptides
AU6092794A (en) Oxime-substituted therapeutic compounds
AU3040589A (en) Homoarginine-based peptides as platelet aggregation inhibitors
AU1397895A (en) Peptide analogs of the activated platelet binding site on factor xi
AU3910793A (en) Stapler
AU3977589A (en) Novel peptides
AU1914292A (en) Composite structures
AU2249192A (en) Calpain-inhibiting peptide analogs of the kininogen heavy chain
AU1398595A (en) Peptide analogs of the factor ixa platelet binding site
AU9131091A (en) Peptides that inhibit platelet binding of adhesion molecules
AU6252394A (en) Therapeutic herbal composition
AU4271793A (en) Novel polypeptide
AU7227494A (en) Inhalator
AU5970094A (en) Construction element