JP6630293B2 - 鉄欠乏症の治療方法 - Google Patents
鉄欠乏症の治療方法 Download PDFInfo
- Publication number
- JP6630293B2 JP6630293B2 JP2016573503A JP2016573503A JP6630293B2 JP 6630293 B2 JP6630293 B2 JP 6630293B2 JP 2016573503 A JP2016573503 A JP 2016573503A JP 2016573503 A JP2016573503 A JP 2016573503A JP 6630293 B2 JP6630293 B2 JP 6630293B2
- Authority
- JP
- Japan
- Prior art keywords
- iron
- biocompatible
- iron oxide
- group
- rats
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462023533P | 2014-07-11 | 2014-07-11 | |
| US62/023,533 | 2014-07-11 | ||
| PCT/CN2015/083765 WO2016004894A1 (en) | 2014-07-11 | 2015-07-10 | Method of treating iron deficiency |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524670A JP2017524670A (ja) | 2017-08-31 |
| JP2017524670A5 JP2017524670A5 (enExample) | 2018-08-16 |
| JP6630293B2 true JP6630293B2 (ja) | 2020-01-15 |
Family
ID=53773226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573503A Active JP6630293B2 (ja) | 2014-07-11 | 2015-07-10 | 鉄欠乏症の治療方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9492399B2 (enExample) |
| EP (1) | EP2965754B1 (enExample) |
| JP (1) | JP6630293B2 (enExample) |
| CN (1) | CN107073035B (enExample) |
| ES (1) | ES2654429T3 (enExample) |
| HU (1) | HUE035242T2 (enExample) |
| PL (1) | PL2965754T3 (enExample) |
| PT (1) | PT2965754T (enExample) |
| TW (1) | TWI689310B (enExample) |
| WO (1) | WO2016004894A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110157000B (zh) | 2018-02-12 | 2022-05-31 | 巨生生医股份有限公司 | 生物相容性磁性材料 |
| WO2024100213A1 (fr) | 2022-11-10 | 2024-05-16 | Université De Lorraine | Nanoclusters de fer, leurs procédés d'obtention et leurs utilisations pour lutter contre les carences en fer |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5248492A (en) | 1986-07-03 | 1993-09-28 | Advanced Magnetics, Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US5554386A (en) | 1986-07-03 | 1996-09-10 | Advanced Magnetics, Inc. | Delivery of therapeutic agents to receptors using polysaccharides |
| US6099852A (en) * | 1998-09-23 | 2000-08-08 | Johnson & Johnson Vision Products, Inc. | Wettable silicone-based lenses |
| US7871597B2 (en) | 1999-04-09 | 2011-01-18 | Amag Pharmaceuticals, Inc. | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
| DE60043188D1 (de) | 1999-04-09 | 2009-12-03 | Amag Pharmaceuticals Inc | Hitzebeständige umhüllte kolloidale eisenoxide |
| US6997863B2 (en) * | 2001-07-25 | 2006-02-14 | Triton Biosystems, Inc. | Thermotherapy via targeted delivery of nanoscale magnetic particles |
| US20030190355A1 (en) | 2002-04-05 | 2003-10-09 | Hermelin Marc S. | Modified release minerals |
| AU2003250971B2 (en) * | 2002-07-24 | 2008-04-03 | F. Hoffmann - La Roche Ag | Polyethylene glycol aldehyde derivatives |
| US7462446B2 (en) | 2005-03-18 | 2008-12-09 | University Of Washington | Magnetic nanoparticle compositions and methods |
| US20110182805A1 (en) | 2005-06-17 | 2011-07-28 | Desimone Joseph M | Nanoparticle fabrication methods, systems, and materials |
| DE102005059751A1 (de) | 2005-12-09 | 2007-06-14 | Ferropharm Gmbh Forschungslabor | Wässrige Dispersion von superparamagnetischen Eindomänenteilchen, deren Herstellung und Verwendung zur Diagnose und Therapie |
| TWI293113B (en) | 2005-12-23 | 2008-02-01 | Ind Tech Res Inst | Magnetic nanoparticles with fluorescent and specific targeting functions |
| PT1973549T (pt) | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
| TWI321133B (en) | 2006-08-01 | 2010-03-01 | Univ Kaohsiung Medical | Folate-receptor-targeting iron oxide nanoparticles coated with poly(ethylene glycol) |
| ES2308901B1 (es) | 2006-09-22 | 2009-10-30 | Consejo Superior De Investigaciones Cientificas | Sistemas que contienen nanoparticulas magneticas y polimeros, como nanocomposites y ferrofluidos, y sus aplicaciones. |
| US20110104073A1 (en) | 2007-01-18 | 2011-05-05 | Qi Zeng | Iron/Iron Oxide Nanoparticle and Use Thereof |
| US20120003160A1 (en) | 2007-06-29 | 2012-01-05 | Amag Pharmaceuticals, Inc. | Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session |
| TWI361082B (en) | 2008-01-15 | 2012-04-01 | Ind Tech Res Inst | Biocompatible polymer and magnetic nanoparticle with biocompatibilities |
| WO2009120702A2 (en) | 2008-03-25 | 2009-10-01 | Emory University | Elemental iron nanoparticles |
| EP2285423B1 (en) * | 2008-04-22 | 2020-03-18 | MegaPro Biomedical Co., Ltd. | Biocompatible polymer and magnetic nanoparticle with biocompatibility |
| US20090280063A1 (en) | 2008-05-09 | 2009-11-12 | General Electric Company | Novel pei-peg graft copolymer coating of iron oxide nanoparticles for inflammation imaging |
| US8179999B2 (en) * | 2008-08-08 | 2012-05-15 | Nokia Corporation | Decoding of blocks in radio communications |
| WO2010034319A1 (en) * | 2008-09-29 | 2010-04-01 | Innovative Research And Development Co. (Inrad) | Magnetite nanoparticles as a single dose treatment for iron deficiency anemia |
| AU2009334868B2 (en) | 2008-12-29 | 2015-11-05 | Ge Healthcare Limited | Nanoparticle contrast agents for diagnostic imaging |
| WO2010091183A2 (en) | 2009-02-04 | 2010-08-12 | The Regents Of The University Of Colorado, A Body Corporate | Non-invasive detection of complement-mediated inflammation using cr2-targeted nanoparticles |
| EP2275137A1 (en) | 2009-07-10 | 2011-01-19 | Nanobiotix | Metallic nanoparticles, preparation and uses thereof |
| GB2472446A (en) | 2009-08-07 | 2011-02-09 | Ct Fuer Angewandte Nanotechnologie | Metal oxide particles coated with polyethylene glycol and their synthesis |
| WO2011052205A1 (ja) * | 2009-10-30 | 2011-05-05 | 国立大学法人東京工業大学 | ポリマー被覆フェライト微粒子および製造方法 |
| US9511151B2 (en) | 2010-11-12 | 2016-12-06 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of cancer |
| WO2012092305A2 (en) * | 2010-12-27 | 2012-07-05 | Incube Labs, Llc | Nanonized iron compositions and methods of use thereof |
| EP2526927A1 (de) * | 2011-05-25 | 2012-11-28 | Justus-Liebig-Universität Gießen | Biokompatible Nano- und Mikropartikel beschichtet mit Stabilisatoren für die pulmonale Applikation |
| CN102349930B (zh) | 2011-11-01 | 2013-07-10 | 东南大学 | 具有抗氧化活性的氧化铁纳米粒水凝胶剂 |
| US9474810B2 (en) * | 2012-03-02 | 2016-10-25 | General Electric Company | Superparamagnetic nanoparticles with PEG substituted α-hydroxy phosphonate shells |
| US9196405B2 (en) | 2012-04-03 | 2015-11-24 | Florida State University Research Foundation, Inc. | Stable iron oxide nanoparticles and method of production |
| EP2647389A1 (en) * | 2012-04-04 | 2013-10-09 | Charité - Universitätsmedizin Berlin | Magnetic nanoparticle dispersion, its preparation and diagnostic and therapeutic use |
| US20150147276A1 (en) | 2012-06-07 | 2015-05-28 | President And Fellows Of Harvard College | Nanotherapeutics for drug targeting |
| US20130336897A1 (en) | 2012-06-18 | 2013-12-19 | Gerald L. Wolf | Theranosis of macrophage-associated diseases with ultrasmall superparamagnetic iron oxide nanoparticles (uspio) |
| CN103251648B (zh) | 2013-05-15 | 2015-08-05 | 乔敏 | 治疗血磷酸盐过多症及缺铁性贫血症的铁基蒙脱石药物及其制备方法 |
| CN103341165B (zh) | 2013-05-31 | 2015-04-01 | 上海师范大学 | 一种具有光热功能的Fe@Fe3O4纳米粒子及其制备方法和应用 |
| CN103303981B (zh) | 2013-07-04 | 2015-04-01 | 厦门大学 | 一种四氧化三铁纳米粒子及其制备方法和用途 |
| CN103405790B (zh) | 2013-07-15 | 2015-05-20 | 中国科学院过程工程研究所 | 一种高分子原位修饰的超顺磁性颗粒、制备方法及其用途 |
| CN103469290B (zh) | 2013-09-02 | 2016-01-13 | 南阳师范学院 | 一种合成超顺磁性Fe3O4纳米晶的方法 |
| CN103601900A (zh) | 2013-11-15 | 2014-02-26 | 无锡中科光远生物材料有限公司 | 一种具有靶向效应的纳米颗粒的制备方法 |
-
2015
- 2015-06-29 TW TW104120956A patent/TWI689310B/zh active
- 2015-07-10 WO PCT/CN2015/083765 patent/WO2016004894A1/en not_active Ceased
- 2015-07-10 CN CN201580035310.XA patent/CN107073035B/zh active Active
- 2015-07-10 US US14/796,332 patent/US9492399B2/en active Active
- 2015-07-10 JP JP2016573503A patent/JP6630293B2/ja active Active
- 2015-07-12 ES ES15176372.9T patent/ES2654429T3/es active Active
- 2015-07-12 PT PT151763729T patent/PT2965754T/pt unknown
- 2015-07-12 HU HUE15176372A patent/HUE035242T2/en unknown
- 2015-07-12 PL PL15176372T patent/PL2965754T3/pl unknown
- 2015-07-12 EP EP15176372.9A patent/EP2965754B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107073035A (zh) | 2017-08-18 |
| WO2016004894A1 (en) | 2016-01-14 |
| TWI689310B (zh) | 2020-04-01 |
| US9492399B2 (en) | 2016-11-15 |
| PL2965754T3 (pl) | 2018-04-30 |
| US20160008292A1 (en) | 2016-01-14 |
| PT2965754T (pt) | 2018-01-08 |
| EP2965754A1 (en) | 2016-01-13 |
| ES2654429T3 (es) | 2018-02-13 |
| TW201625278A (zh) | 2016-07-16 |
| CN107073035B (zh) | 2020-08-28 |
| HUE035242T2 (en) | 2018-05-02 |
| JP2017524670A (ja) | 2017-08-31 |
| EP2965754B1 (en) | 2017-10-04 |
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