JP6532529B2 - ミソプロストール分散性錠剤 - Google Patents

ミソプロストール分散性錠剤 Download PDF

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Publication number
JP6532529B2
JP6532529B2 JP2017521290A JP2017521290A JP6532529B2 JP 6532529 B2 JP6532529 B2 JP 6532529B2 JP 2017521290 A JP2017521290 A JP 2017521290A JP 2017521290 A JP2017521290 A JP 2017521290A JP 6532529 B2 JP6532529 B2 JP 6532529B2
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Japan
Prior art keywords
pharmaceutical composition
weight
composition according
seconds
tablet
Prior art date
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Application number
JP2017521290A
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English (en)
Japanese (ja)
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JP2017520628A (ja
JP2017520628A5 (enExample
Inventor
セルバラージ，セカール
エルマレイ，バスカール
アルナーチャラム，マライアラサン
ベヌゴパール，プラバカラン
Original Assignee
アサンタ・デンマーク・アー／エス
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Publication date
Priority claimed from EP14176821.8A external-priority patent/EP2965750B1/en
Priority claimed from US14/329,023 external-priority patent/US20160008310A1/en
Application filed by アサンタ・デンマーク・アー／エス filed Critical アサンタ・デンマーク・アー／エス
Publication of JP2017520628A publication Critical patent/JP2017520628A/ja
Publication of JP2017520628A5 publication Critical patent/JP2017520628A5/ja
Priority to JP2019094296A priority Critical patent/JP6921894B2/ja
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Publication of JP6532529B2 publication Critical patent/JP6532529B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2017521290A 2014-07-11 2015-07-10 ミソプロストール分散性錠剤 Active JP6532529B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019094296A JP6921894B2 (ja) 2014-07-11 2019-05-20 ミソプロストール分散性錠剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14176821.8 2014-07-11
EP14176821.8A EP2965750B1 (en) 2014-07-11 2014-07-11 Misoprostol dispersible tablet
US14/329,023 US20160008310A1 (en) 2014-07-11 2014-07-11 Misoprostol dispersible tablet
US14/329,023 2014-07-11
PCT/DK2015/050216 WO2016004960A2 (en) 2014-07-11 2015-07-10 Misoprostol dispersible tablet

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019094296A Division JP6921894B2 (ja) 2014-07-11 2019-05-20 ミソプロストール分散性錠剤

Publications (3)

Publication Number Publication Date
JP2017520628A JP2017520628A (ja) 2017-07-27
JP2017520628A5 JP2017520628A5 (enExample) 2018-08-09
JP6532529B2 true JP6532529B2 (ja) 2019-06-19

Family

ID=53879283

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017521290A Active JP6532529B2 (ja) 2014-07-11 2015-07-10 ミソプロストール分散性錠剤
JP2019094296A Active JP6921894B2 (ja) 2014-07-11 2019-05-20 ミソプロストール分散性錠剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019094296A Active JP6921894B2 (ja) 2014-07-11 2019-05-20 ミソプロストール分散性錠剤

Country Status (15)

Country Link
US (2) US11406615B2 (enExample)
EP (1) EP3166597B1 (enExample)
JP (2) JP6532529B2 (enExample)
AU (1) AU2015287186B2 (enExample)
BR (1) BR112017000529A2 (enExample)
CA (1) CA2954086C (enExample)
DK (1) DK3166597T3 (enExample)
EA (1) EA039069B1 (enExample)
FI (1) FI3166597T3 (enExample)
MX (1) MX392771B (enExample)
NZ (1) NZ727876A (enExample)
PL (1) PL3166597T3 (enExample)
RU (1) RU2017104233A (enExample)
TN (1) TN2017000003A1 (enExample)
WO (1) WO2016004960A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108434110B (zh) * 2018-04-28 2019-09-10 浙江仙琚制药股份有限公司 米索前列醇组合物、片剂及其用途

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB994518A (en) 1962-07-18 1965-06-10 Needle Industries Ltd Improvements relating to shavers
US4301146A (en) * 1980-07-29 1981-11-17 G. D. Searle & Co. Stabilization of 16-oxygenated prostanoic acid derivatives
US4335097A (en) 1981-01-15 1982-06-15 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. Stabilized, prostaglandin-containing tablets with controlled rate of solubility, for local use and process for the preparation thereof
JPH06199779A (ja) 1992-06-08 1994-07-19 Newpharma Internatl Corp トランス−▲δ２▼−１５−デオキシ−１６−ヒドロキシ−１６−メチル−ｐｇ▲ｅ１▼のメチルエステル（ｂ−４０７）
EP0574185B1 (en) 1992-06-08 1997-09-03 Newpharma International Corporation PGE1 analogs
GB9419566D0 (en) * 1994-09-27 1994-11-16 El Refaey Hazem Oral prostagladins for the routine management of the third stage of labour
US5993856A (en) 1997-01-24 1999-11-30 Femmepharma Pharmaceutical preparations and methods for their administration
US6228213B1 (en) 1997-09-19 2001-05-08 University Of Nebraska-Lincoln Production of microcrystalline cellulose by reactive extrusion
US7815937B2 (en) 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
US6526980B1 (en) 1999-08-26 2003-03-04 West Virginia University Cervical drug delivery system
KR20020062323A (ko) * 1999-12-06 2002-07-25 펜웨스트 파머슈티칼즈 컴파니 제약학적 초붕해제
GB2375303A (en) 2001-05-11 2002-11-13 Medical Res Council Method of inducing cervical ripening
GB0204771D0 (en) * 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
SI21221A (sl) 2002-06-21 2003-12-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Hitro razpadljive tablete
TW200502000A (en) * 2003-03-28 2005-01-16 Kyowa Hakko Kogyo Kk Dividing tablet
WO2006125450A1 (en) 2005-05-26 2006-11-30 Atef Mohammed Mostafa Darwish Rectal and vaginal suppositories containing misoprostol
WO2006133048A2 (en) 2005-06-03 2006-12-14 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same
EP1906937B1 (en) * 2005-07-22 2016-10-19 Rubicon Research Pvt Ltd. Novel dispersible tablet composition
US7799530B2 (en) 2005-09-23 2010-09-21 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
WO2007035954A2 (en) 2005-09-23 2007-03-29 Duramed Pharmaceuticals, Inc. Vaginal tablets comprising misoprostol and methods of making and using the same
CN1939308A (zh) 2005-09-28 2007-04-04 应圣俊 一种米索前列醇栓剂
EP1987820A1 (en) 2007-05-04 2008-11-05 Christian Fiala, Ph. D. Slow release misoprostol for obstetric and/or gynaecological applications
EP2572705B1 (en) * 2007-10-01 2017-09-13 Laboratorios Lesvi, S.L. Orodispersible tablets
WO2009154810A2 (en) * 2008-02-25 2009-12-23 Dr. Reddy's Laboratories Ltd. Delivery systems for multiple active agents
WO2010036878A1 (en) 2008-09-26 2010-04-01 The Trustees Of Columbia University In The City Of New York Use of trpv1 receptor agonists in cervical pain and labor
US20120077888A1 (en) 2009-03-26 2012-03-29 Royal College Of Surgeons In Ireland Orodispersible tablets
US20100260825A1 (en) 2009-04-13 2010-10-14 Nair Madhavan G Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches
RU2394814C1 (ru) 2009-05-22 2010-07-20 Учреждение Российской академии наук Институт органической химии Уфимского научного центра РАН Средство, представляющее собой этиловый эфир (±)-11,15-дидезокси-16-метил-16-гидроксипростагландина e1, проявляющее утеротоническую активность
PL2579866T3 (pl) 2010-06-11 2017-01-31 Ferring B.V. Dopochwowe podawanie mizoprostolu
CN102302443B (zh) 2011-09-21 2014-04-23 天津市聚星康华医药科技有限公司 一种米索前列醇阴道缓释栓剂及其制备方法
CN102697746B (zh) * 2012-06-11 2014-03-19 广州朗圣药业有限公司 一种快速融变的米索前列醇阴道用组合物及其制备方法和应用
EP2689781A1 (en) 2012-07-26 2014-01-29 Ferring B.V. Misoprostol composition
CN104487077A (zh) 2012-07-26 2015-04-01 辉凌公司 米索前列醇制剂
KR20150038174A (ko) 2012-07-26 2015-04-08 훼링 비.브이. 미소프로스톨 조성물
EP2689802A1 (en) 2012-07-26 2014-01-29 Ferring B.V. Misoprostol formulation
CN102872024B (zh) * 2012-09-28 2015-06-17 天津市聚星康华医药科技有限公司 口腔内使用的米索前列醇药物组合物
CN103040842B (zh) 2012-12-08 2014-11-12 浙江圣博康药业有限公司 一种前列腺素类药物组合物及其制成的前列腺素类药物栓剂
CN103340837B (zh) * 2013-07-08 2018-04-27 天津市聚星康华医药科技有限公司 一种米索前列醇阴道泡腾片及其制备方法

Also Published As

Publication number Publication date
WO2016004960A2 (en) 2016-01-14
CA2954086A1 (en) 2016-01-14
AU2015287186A1 (en) 2017-01-19
JP2017520628A (ja) 2017-07-27
EP3166597A2 (en) 2017-05-17
WO2016004960A3 (en) 2016-03-17
RU2017104233A3 (enExample) 2018-12-18
NZ727876A (en) 2018-05-25
JP6921894B2 (ja) 2021-08-18
PL3166597T3 (pl) 2025-11-17
EA039069B1 (ru) 2021-11-30
MX392771B (es) 2025-03-24
FI3166597T3 (fi) 2025-09-16
DK3166597T3 (en) 2025-09-01
US12005041B2 (en) 2024-06-11
CA2954086C (en) 2020-03-31
AU2015287186B2 (en) 2018-05-31
RU2017104233A (ru) 2018-08-13
US20220347145A1 (en) 2022-11-03
MX2017000399A (es) 2017-08-10
US20210322356A1 (en) 2021-10-21
US11406615B2 (en) 2022-08-09
BR112017000529A2 (pt) 2017-11-14
EP3166597B1 (en) 2025-08-06
EA201692536A1 (ru) 2017-06-30
JP2019147831A (ja) 2019-09-05
TN2017000003A1 (en) 2018-07-04

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